DEHALOGENASE

作品数：13被引量：9H指数：2
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Correction on “Understanding the cooperative effects in the catalysis of homodimeric fluoroacetate dehalogenase” [Sci. China Chem., 2024, 67, 2382‒2391, https://doi.org/10.1007/s11426-024- 1999-1]
《Science China Chemistry》2025年第2期802-802,共1页Ke-Wei Chen Jia-Nan Chen Jun Zhang Chao Wang Tian-Yu Sun Yun-Dong Wu 
In the third line of the second paragraph of Section 2.1,“Gaff2”should be“GAFF2”.There is no space between“atomsto”in the first sentence of the last paragraph of Section 2.2.It should be“First,the initial struc...
关键词：restrain eliminate SENTENCE 
Characterization of the dissociation pathways of dichloromethane and glutathione in dichloromethane dehalogenase
《南京大学学报（自然科学版）》2024年第4期651-660,共10页Gao Xudan Zhang Huizhu Mei Ye 
National Natural Science Foundation of China(22073030);the Oriental Scholars of Shanghai Universities。
Dichloromethane(DCM)dehalogenase stands as a crucial enzyme implicated in the degradation of methylene chloride across diverse environmental and biological contexts.However,the unbinding pathways of ligands from DCM d...
关键词：DCM dehalogenase GSH Alphafold2 RAMD unbinding pathways 
Understanding the cooperative effects in the catalysis of homodimeric fluoroacetate dehalogenase
《Science China Chemistry》2024年第7期2382-2391,共10页Ke-Wei Chen Jia-Nan Chen Jun Zhang Chao Wang Tian-Yu Sun Yun-Dong Wu 
supported by the Key-Area Research and Development Program of Guangdong Province(2020B0101350001);the Shenzhen Fundamental Research Program(GXWD2020123116580700720200812124825001);the Shenzhen Science and Technology Program(RCBS20210706092258097);supported by the Shenzhen Bay Laboratory Supercomputing Center。
Fluoroacetate dehalogenases(FAcD),a homodimeric enzyme,catalyzes the conversion of fluoroacetic acid to glycolic acid(GoA).It has been proved that the enzyme has a half-of-the-site reactivity.Namely,its catalytic(C)su...
关键词：enzyme catalysis molecular dynamics cooperative effect pre-reaction state 
Engineering and characterization of dehalogenase enzymes from Delftia acidovorans in bioremediation of perfluorinated compounds被引量：2
《Synthetic and Systems Biotechnology》2022年第2期683-688,共6页Jackson D.Harris Collin M.Coon Megan E.Doherty Eamon A.McHugh Margaret C.Warner Conley L.Walters Olivia M.Orahood Abigail E.Loesch David C.Hatfield John C.Sitko Erin A.Almand J.Jordan Steel 
Per-and Polyfluorinated alkyl substances(PFAS)are a broad class of synthetic compounds that have fluorine substituted for hydrogen in several or all locations and are globally categorized as PFCs(perfluorochemicals;co...
关键词：iGEM PFAS BIOREMEDIATION BIOENGINEERING Delftia acidovorans 
Structure-guided protein design of fluoroacetate dehalogenase for kinetic resolution of rac-2-bromobutyric acid
《Green Synthesis and Catalysis》2020年第1期60-65,共6页Shu Wang Zhanbing Cheng Yanbing Xu Lu Yang Jian-Bo Wang Zhenhua Tian Xudong Qu 
R-2-Bromobutyric acid is a very important intermediate for the synthesis of agrochemicals and pharmaceuticals.Bioresolution of rac-2-bromobutyric acid(rac-2-BBA)provides a promising process for R-2-bromobutyric acid(R...
关键词：Fluoroacetate dehalogenase Semi-rational design Enzyme engineering Kinetic resolution 2-bromobutyric acid 
Individual stages of bacterial dichloromethane degradation mapped by carbon and chlorine stable isotope analysis
《Journal of Environmental Sciences》2019年第4期147-160,共14页Maria L.Torgonskaya Anatoly M.Zyakun Yuri A.Trotsenko Kestutis S.Laurinavichius Steffen Kümmel Stéphane Vuilleumier Hans H.Richnow 
supported by the Russian Foundation of Basic Research, Russia; (Nos. 06-04-22000, 12-04-00760, and 15-0404458);the Centre National de la Recherche Scientifique, France; CNRS (No. PICS 3380);supported by REALISE, the Alsace Research Network in Environmental Sciences;supported by EUEU Marie Curie Host Fellowships (BIOISOTOPE Contract EVK1-CT-2000-56120)
The fractionation of carbon and chlorine stable isotopes of dichloromethane(CH_2Cl_2,DCM)upon dechlorination by cells of the aerobic methylotroph Methylobacterium extorquens DM4 and by purified DCM dehalogenases of th...
关键词：Dichloromethane(DCM) Microbial DEGRADATION Aerobic methylotrophic bacteria DICHLOROMETHANE DEHALOGENASE CARBON and CHLORINE isotopic FRACTIONATION 
Fluoroacetate in plants - a review of its distribution, toxicity to livestock and microbial detoxification被引量：2
《Journal of Animal Science and Biotechnology》2017年第4期813-823,共11页Lex Ee Xiang Leong Shahjalal Khan Carl K. Davis Stuart E. Denman Chris S. McSweeney 
supported by Meat & Livestock Australia (MLA)
Fluoroacetate producing plants grow worldwide and it is believed they produce this toxic compound as a defence mechanism against grazing by herbivores. Ingestion by livestock often results in fatal poisonings, which c...
关键词：AEROBIC Anaerobic Degradation DEHALOGENASE FLUOROACETATE 1080 Synergistetes TCA TOXICITY 
Purification and Characterization of 2-Haloacid Dehalogenase from Marine Bacterium Paracoccus sp. DEH99, Isolated from Marine Sponge Hymeniacidon perlevis被引量：2
《Journal of Ocean University of China》2014年第1期91-96,共6页ZHANG Jinyou XIN Yanjuan CAO Xupeng XUE Song ZHANG Wei 
supported by National Basic Research Program of China(973 program,Grant No.2009CB724700);the Hundred Talent Program of the Chinese Academy of Sciences(A1097);National Natural Science Foundation of China(No.31100092)
2-haloacid dehalogenases constitute a group of dehalogenases which are capable of dehalogenating the halogenated organic compounds. So far, the 2-haloacid dehalogenases have been found in many bacteria, but not in Par...
关键词：PARACOCCUS sp 2-Haloacid DEHALOGENASE PURIFICATION MARINE BACTERIUM MARINE SPONGE 
Evaluation of Transgenic <i>Nicotiana tabacum</i>with <i>deh</i>E Gene Using Transposon Based IRAP Markers
《American Journal of Plant Sciences》2013年第8期41-44,共4页Yilmaz Kaya Sibel Yilmaz Nermin Gozukirmizi Fahrul Huyop 
In the present study, five genetically modified herbicide tolerant Nicotiana tabacum cv. TAPM24 plants with a constructed vector pCAMBIA1301a carrying dehalogenase E (dehE) gene were compared with three non-transgenic...
关键词：Nicotiana tabacum DEHALOGENASE E Tto1 RETROTRANSPOSON IRAP TRANSGENICS 
Characteristics of dehalogenase from bacteria isolated from the Gut of Pond-reared Rohu (<i>Labeo rohita</i>) Juveniles in Myanmar
《Advances in Bioscience and Biotechnology》2012年第4期353-361,共9页Eleanor Abel Rolando V. Pakingking Jr. Gregoria Gregoria May Thanda Wint Fahrul Huyop 
Unwarranted accumulation of halogenated compounds in the rivers and streams has in recent years emerged due to the widespread use agricultural pesticides. The presence of these halogenated compounds in the water does ...
关键词：2 2-Dichloropropionic ACID 16S rDNA Labeo rohita DEHALOGENASE Gene Biodegradation Haloalkanoic ACID Dichloropropionate 
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