MIMICRY

作品数:77被引量:162H指数:8
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相关领域:医药卫生更多>>
相关作者:欧光朔缪家顺詹妮冯圣军朱祝军更多>>
相关机构:四川省肿瘤医院中国人民解放军总医院中国科学院剑桥大学更多>>
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相关基金:国家自然科学基金中国博士后科学基金The Royal Society霍英东教育基金更多>>
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Virome-wide analysis of histone modification mimicry motifs carried by viral proteins
《Virologica Sinica》2024年第5期793-801,共9页Yang Xiao Shuofeng Yuan Ye Qiu Xing-Yi Ge 
funded by the National Natural Science Foundation of China(No.U2002218,32270170 and 81902070);the Fund of Hunan University(521119400156);the Science and Technology Innovation Program of Hunan Province(2024RC1028).
Histone mimicry(HM)refers to the presence of short linear motifs in viral proteins that mimic critical regions of host histone proteins.These motifs have the potential to interfere with host cell epigenome and counter...
关键词:Histone mimicry Viral proteins Histone modification EVOLUTION CORONAVIRUS 
A repertoire of intronic lariat RNAs reveals tissue-specific regulation and target mimicry potential in plants
《Science China(Life Sciences)》2024年第6期1280-1291,共12页Yong Zhang Xiaotuo Zhang Qi Tang Lei Li Ting Jiang Yixiao Fang Hong Zhang Jixian Zhai Guodong Ren Binglian Zheng 
supported by the National Natural Science Foundation of China(31830045,32025005,32100429)。
Lariat RNA is concomitantly produced by excised intron during RNA splicing,which is usually debranched by DBR1,an RNA debranching enzyme.However,increasing evidence showed that some lariat RNA could escape debranching...
关键词:intron turnover lariat RNA miRNA RNA splicing DBR1 
Insm1:orchestrating cellular mimicry in the thymus medulla
《Cellular & Molecular Immunology》2024年第4期414-416,共3页K.D.James J.E.Cowan 
funded by the Wellcome Trust and the Royal Society(Grant Number 222623/Z/21/Z);KDJ is a Post-Doctoral Fellow supported by an MRC Programme Grant(MR/T029765/1)awarded to Professor Graham Anderson.
The thymus is the primary production site for a functional and self-tolerant T-cell repertoire.The establishment of immune tolerance is mediated by the generation and presentation of tissue-restricted self-antigens(TR...
关键词:MEDULLARY eliminate RESTRICTED 
Biological scaffold as potential platforms for stem cells:Current development and applications in wound healing
《World Journal of Stem Cells》2024年第4期334-352,共19页Jie-Yu Xiang Lin Kang Zi-Ming Li Song-Lu Tseng Li-Quan Wang Tian-Hao Li Zhu-Jun Li Jiu-Zuo Huang Nan-Ze Yu Xiao Long 
Supported by CAMS Innovation Fund for Medical Sciences,No.2020-I2M-C&T-A-004;National High Level Hospital Clinical Research Funding,No.2022-PUMCH-A-210,No.2022-PUMCH-B-041,and No.2022-PUMCH-C-025;and National Key R&D Program of China,No.2020YFE0201600.
Wound repair is a complex challenge for both clinical practitioners and researchers.Conventional approaches for wound repair have several limitations.Stem cell-based therapy has emerged as a novel strategy to address ...
关键词:Stem-cell-based therapy Biological scaffolds Wound healing Extracellular matrix mimicry Cellular activities enhancement Scaffold characteristics 
On-chip physiological mimicry of neurovascular unit: challenges and perspectives
《Neural Regeneration Research》2024年第3期499-500,共2页Song Ih Ahn YongTae Kim 
supported by a 2-Year Research Grant of Pusan National University(to SIA).
Neurological disorders including neurodegenerative diseases,brain tumors,and stroke are the second leading cause of death and the greatest cause of disability worldwide.However,it remains challenging to achieve effect...
关键词:DISEASES DEATH ARTERIES 
Platycodin D inhibits angiogenic vascular mimicry in NSCLC by regulating the eIF4E-mediated RNA methylome被引量:1
《Journal of Pharmaceutical Analysis》2024年第1期152-155,共4页Shuyu Zheng Yanlin Xin Jiamin Lin Zejuan Xie Keyu Cheng Shanshan Wang Wenli Lu Hao Yang Tianming Lu Jun Li Ruogu Qi Yuanyuan Guo 
funded by the National Natural Science Foundation of China(Grant Nos.:82004081 and 52073145);the National Natural Science Foundation of Nanjing University of Chinese Medicine,China(Grant No.:NZY82004081).
The treatment of non-small cell lung cancer(NSCLC)remains a challenge due to tumor evolution during anti-angiogenesis therapies,in which the mechanism of vascular mimicry(VM)is believed to result in ineffective treatm...
关键词:NSCLC EIF4E treatment 
Pathogen Protein Modularity Enables Elaborate Mimicry of a Host Phosphatase
《Bulletin of the Chinese Academy of Sciences》2023年第2期125-126,共2页WANG Yanli 
Pathogens have developed an extensive array of proteins during the co-evolutionary arms race with their hosts.This is particularly true for Phytophthora,a genus that causes significant damage to agriculture and forest...
关键词:blight PHYTOPHTHORA development. 
On challenges of AI to cognitive security and safety被引量:1
《Security and Safety》2023年第2期44-56,共13页Ruiyang Huang Xiaoqing Zheng Yuting Shang Xiangyang Xue 
supported in part by National Key R&D Plan(2022YFB3102901)
Recent advances in deep learning have led to disruptive breakthroughs in artificial intelligence(AI),fueling the jump in ChatGPT-like large language models(LLMs).As with any emerging technology,it is a two-sided coin,...
关键词:Cognitive security Artificial intelligence Endogenous safety and security Mimicry intelligence 
Glutathione peroxidase mimicry of diphenyl diselenide: Plausible contribution of proteins’ thiols
《Toxicology Advances》2023年第2期14-20,共7页Ebenezer Morayo Ale Steve Osagie Asuelimen Olawale Otitoju 
Organoseleniums are a class of compounds attracting attention across the globe owing to their Glutathione peroxidase(GPx)mimicry,which confers on them a strong antioxidant activity.Diphenyl diselenide(DPDS)is an Organ...
关键词:Organoseleniums diphenyl diselenide Glutathione peroxidase ANTIOXIDANT THIOLS delta-aminolevulinic acid dehydratase Na^(+)/K^(+)-ATPase 
Biology and resource acquisition of mistletoes,and the defense responses of host plants被引量:1
《Ecological Processes》2022年第1期332-344,共13页Meseret Muche A.Muthama Muasya Berhanu Abraha Tsegay 
Background:Mistletoes are the most successful group of obligatory hemi-parasitic flowering plants that attach to the host via haustorium for obtaining water and minerals.This review aims to assess the current knowledg...
关键词:Biotic stress HAUSTORIUM Host defense MISTLETOES MIMICRY Resource procurement 
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