THYMUS

作品数：161被引量：250H指数：8
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Donor MHC-specific thymus vaccination allows for immunocompatible allotransplantation
《Cell Research》2025年第2期132-144,共13页Yang Liu Hexi Feng Ke Li Ruiyi Li Xiao-Jie Zhang Ye Tian Yujiang Fang Yanjie Zhou Ling Liu Xiaoqing Zhang 
supported by grants from the National Natural Science Foundation of China(82025020,82230072 and 32270874);the National Key R&D Program of China(2021YFA1100400 and 2021YFC2701400);the Science and Technology Commission of Shanghai Municipality(21140902300 and 22ZR1464000);Major Program of Development Fund for Shanghai Zhangjiang National Innovation Demonstration Zone(ZJ2018-ZD-004);Medical Research Project of Jing’an District,Shanghai(2023ZX03);Shanghai Municipal Health Commission(202240011);Peak Disciplines(Type IV)of Institutions of Higher Learning in Shanghai;sponsored by Shanghai Blue Cross Brain Hospital Co.,Ltd.,and Shanghai Tongji University Education Development Foundation.
Organ transplantation is the last-resort option to treat organ failure.However,less than 10%of patients benefit from this only option due to lack of major histocompatibility complex(MHC)-matched donor organs and 25%–...
关键词：VACCINATION ORGANS DONOR 
Selenium deficiency exacerbates ROS/ER stress mediated pyroptosis and ferroptosis induced by bisphenol A in chickens thymus
《Journal of Environmental Sciences》2025年第2期13-26,共14页Kun Wang Xu Shi Hongjin Lin Tong Xu Shiwen Xu 
supported by the National Natural Science Foundation of China Regional Joint Innovation Fund (No.U22A20524);the Heilongjiang Province Natural Science Foundation Key projects (No.ZD2023C002).
Bisphenol A(BPA)is an industrial pollutant that can cause immune impairment.Selenium acts as an antioxidant,as selenium deficiency often accompanies oxidative stress,resulting in organ damage.This study is the first t...
关键词：Bisphenol A Selenium deficiency ROS/ER stress PYROPTOSIS Ferroptosis Thymic injury 
Thymus serpyllum L.Essential Oil:Phytochemistry and in Vitro and in Silico Screening of Its Antimicrobial,Antioxidant and Anti-Inflammatory Properties
《Phyton-International Journal of Experimental Botany》2025年第1期209-227,共19页Samiah Hamad Al-Mijalli Hanae Naceiri Mrabti Amine Elbouzidi Naglaa S.Ashmawy Amine Batbat Emad M.Abdallah Wafa Laaboudi Mohammed Aladhadh Fahad M.Alshabrmi Sulaiman Mohammed Alnasser Mohamed Addi Naoufal El Hachlafi 
Thymus serpyllum L.,often known as wild thyme,has been used since ancient times due to its multifaceted culinary and medicinal attributes.It is usually utilized in folk medicine to manage different health issues.This ...
关键词：Thymus serpyllum GC-MS ANTIMICROBIAL oxidative stress ANTI-INFLAMMATORY in silico 
Enigmatic thymus: Variations in anatomical localisation of thymic tissue as an easily misdiagnosed congenital anomaly in surgical practice
《World Journal of Clinical Cases》2024年第25期5646-5652,共7页Alexander Mayer Jaroslav Voller Ivan Varga 
We point out the issue of differential diagnosis regarding the finding of ectopically localised thymic tissue(a thymic cyst)in the neck.Thymic tissue can be found anywhere along its developmental tract of descent,from...
关键词：THYMUS Thymic anomalies Thymic ectopy Congenital cervical thymic cyst Embryonic development 
TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice被引量：1
《Cellular & Molecular Immunology》2024年第8期807-825,共19页Mario Ruiz Pérez Christian Maueröder Wolf Steels Bruno Verstraeten Sahine Lameire Wei Xie Laura Wyckaert Jelle Huysentruyt Tatyana Divert Ria Roelandt Amanda Gonçalves Riet De Rycke Kodi Ravichandran Bart N.Lambrecht Tom Taghon Georges Leclercq Peter Vandenabeele Peter Tougaard 
FWO Research Grants G.0B96.20N(PV,PT),G.0C76.18N(PV),G.0B71.18N(PV);G.0A93.22N(PV);Special Research Fund UGent(Methusalem grant BOF16/MET_V/007(PV);BOF22/MET_V/007(PV);iBOF ATLANTIS grant 20/IBF/039(PV));EOS MODEL-IDI Grant(30826052)(PV);EOS CD-INFLADIS(40007512)(PV);Foundation against Cancer(F/2016/865,F/2020/1505)(PV).FWO fundamental research fellowship PhD grant(MRP)(11A7222N);FWO senior postdoctoral fellowship(CM)(12Y2122N);DFG research fellowship(CM)(MA 7770/1-1);Cancer Research Institute Ghent(CRIG)consortia;Ghent Gut Inflammation Group(GGIG)consortia.Flanders Institute for Biotechnology(VIB).
Acute systemic inflammation critically alters the function of the immune system,often promoting myelopoiesis at the expense of lymphopoiesis.In the thymus,systemic inflammation results in acute thymic atrophy and,cons...
关键词：Thymic Neutrophils Emergency granulopoiesis Thymus atrophy Thymic GMP Cytokine synergy 
Selectively T cell phosphorylation activation of azvudine in the thymus tissue with immune protection effect
《Acta Pharmaceutica Sinica B》2024年第7期3140-3154,共15页Ning Sheng Rui Li Yang Li Zhe Wang Lulu Wang Yuhuan Li Jinlan Zhang Jiandong Jiang 
the National Natural Science Foundation of China(No.82151525;No.82394460);the National Key Research and Development Program of China(No.2021YFC0864600).
Thymus is the important immune organ,responsible for T cell development and differentiation.The lower circulating T counts have been observed in patients who died from COVID-19 compared with survivors.Azvudine,also kn...
关键词：Azvudine T cell THYMUS Phosphorylation activation Nucleoside analogue 
Insm1:orchestrating cellular mimicry in the thymus medulla
《Cellular & Molecular Immunology》2024年第4期414-416,共3页K.D.James J.E.Cowan 
funded by the Wellcome Trust and the Royal Society(Grant Number 222623/Z/21/Z);KDJ is a Post-Doctoral Fellow supported by an MRC Programme Grant(MR/T029765/1)awarded to Professor Graham Anderson.
The thymus is the primary production site for a functional and self-tolerant T-cell repertoire.The establishment of immune tolerance is mediated by the generation and presentation of tissue-restricted self-antigens(TR...
关键词：MEDULLARY eliminate RESTRICTED 
Plant growth-promoting properties and anti-fungal activity of endophytic bacterial strains isolated from Thymus altaicus and Salvia deserta in arid lands
《Journal of Arid Land》2023年第11期1405-1420,共16页ZHAO Mengqi SU Huan HUANG Yin Rashidin ABDUGHENI MA Jinbiao GAO Jiangtao GUO Fei LI Li 
financially supported by the Third Xinjiang Comprehensive Scientific Expedition (2022xjkk020605);the Xinjiang Uygur Autonomous Region Regional Coordinated Innovation Project (Shanghai Cooperation Organization Science and Technology Partnership Program) (2020E01047);supported by the Introduction Project of High-level Talents in Xinjiang Uygur Autonomous Region, China
Endophytes,as crucial components of plant microbial communities,significantly contribute to enhancing the absorption of nutrients such as nitrogen and phosphorus by their hosts,promote plant growth,and degrade pathoge...
关键词：endophytic bacteria Thymus altaicus Salvia deserta pathogenic fungi plant growth-promoting properties anti-fungal activity 
In Vitro Evaluation of the Antifungal Activity of Essential Oils of Thymus vulgaris and Cymbopogon citratus on Some Strains of Sclerotinia sclerotiorum, Agent Responsible for White Rot of Beans
《Agricultural Sciences》2023年第8期1068-1086,共19页Serge Bertrand Mboussi Alain Heu Abdou Nourou Kone Nsangou Jules Patrice Ngoh Dooh Zachée Ambang 
The present work was aimed to the study of the antifungal activity of essential oils of two aromatic plants against three strains of Sclerotinia sclerotiorum responsible for white rot of bean. The two essential oils (...
关键词：S. sclerotiorum T. vulgaris C. Citratrus Essential Oils Antifungal Activity INHIBITION 
Surgical resection of a giant thymolipoma causing respiratory failure: A case report
《World Journal of Clinical Cases》2023年第5期1137-1143,共7页Liang-Hui Gong Wen-Xiang Wang Yong Zhou De-Song Yang Bai-Hua Zhang Jie Wu 
Supported by Hunan Provincial Natural Science Foundation of China,No. 2022JJ40246;Hunan Cancer Hospital Climb Plan,No. 2021NSFC-B005。
BACKGROUND Thymolipoma is a rare benign tumor arising from the anterior mediastinal thymus and is composed of mature fatty tissue and interspersed nonneoplastic thymic tissue. This tumor accounts for only a small perc...
关键词：Thymolipomas Thymus neoplasm Respiratory insufficiency Anterior mediastinal mass Posterolateral thoracotomy Case report 
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