SINGLE-DOMAIN

作品数:19被引量:12H指数:2
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A single-domain protein catenane of dihydrofolate reductase被引量:1
《National Science Review》2023年第11期123-132,共10页Jing Fang Tianzuo Li Jiyeon Lee Dahye Im Lianjie Xu Yajie Liu Jongcheol Seo Wen-Bin Zhang 
supported by the National Key Research and Development Program of China(2020YFA0908100);the National Natural Science Foundation ofChina(21991132,21925102,92056118,22101010,22201016 and 22201017);the Beijing National Laboratory for Molecular Sciences(BNLMS-CXXM202006);the National Research Foundation of Korea(2019R1C1C1008414 and 2020R1A5A1019141)。
A single-domain protein catenane refers to two mechanically interlocked polypeptide rings that fold synergistically into a compact and integrated structure,which is extremely rare in nature.Here,we report a single-dom...
关键词:cellular synthesis CATENANE protein domain chemical topology DHFR 
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