X.Ji acknowledges funding from the National Natural Science Foundation of China(No.22001087);X.Ji also appreciates the support from the Huazhong University of Science and Technology,where he is being supported by Fundamental Research Funds for the Central Universities(Grant 2020kfyXJJS013);X.Ji appreciates support from the Interdisciplinary Research Program of HUST(2023JCYJ013).
Polycatenane gels have attracted extensive attention due to their high degree of freedom and mobility.However,the syntheses of poly[2]catenane gels reported to date all rely on the polymer as the backbone.Herein,we pr...
supported by the National Natural Science Foundation of China(22101108,22171123);the Natural Science Foundation of Henan Province(242300421139).
In recent decades,sophisticated supramolecular compounds have attracted widespread attention from the scientific community due to their interesting topological configuration and various application pros-pects in biosi...
the National Natural Science Foundation of China(grant nos.21991132,21925102,92056118,22101010,22201017,and 22201016);the National Key R&D Program of China(grant no.2020YFA0908100);Beijing National Laboratory for Molecular Sciences(grant no.BNLMS-CXXM-202006);supported by the National Center for Protein Sciences at Peking University.
Unlike small molecules,the topological complexity of macromolecules remains largely unexplored due to the huge synthetic challenge.Herein,we report the development of orthogonal active templates for concise and select...
support from the National Natural Science Foundation of China(grant nos.21991132,21925102,92056118,22101010,22201016,and 22201017);the National Key R&D Program of China(grant no.2020YFA0908100);the Beijing National Laboratory for Molecular Sciences(grant no.BNLMSCXXM-202006)。
The expansion of protein topological diversity requires new and efficient synthetic tools.Herein,we report the second and third generations of the SpyStapler-mediated SpyTag/BDTag ligation system for the efficient syn...
the National Natural Science Foundation of China(Nos.92056116,21871194,21971169);National Key Research and Development Program of China(No.2017YFA0505903).
Four pillar[5]arene-based bicyclic compounds,so-called molecular universal joint(MUJ),were synthesized by incorporating a bisamide ring containing N,O,or S-heteroatom groups,which served as stimuli-responsive chiropti...
We are grateful for the financial support from the National Key R&D Program of China(No.2020YFA0908100);the National Natural Science Foundation of China(Nos.21991132,21925102,92056118,22101010,22201016,22201017);Beijing National Laboratory for Molecular Sciences(BNLMS-CXXM-202006)。
Chemical topology refers to the three-dimensional arrangement(i.e.,connectivity and spatial relationship)of a molecule's constituent atoms and bonds.The molecular mechanism for translation defines the linear configura...
supported by the National Key Research and Development Program of China(2020YFA0908100);the National Natural Science Foundation ofChina(21991132,21925102,92056118,22101010,22201016 and 22201017);the Beijing National Laboratory for Molecular Sciences(BNLMS-CXXM202006);the National Research Foundation of Korea(2019R1C1C1008414 and 2020R1A5A1019141)。
A single-domain protein catenane refers to two mechanically interlocked polypeptide rings that fold synergistically into a compact and integrated structure,which is extremely rare in nature.Here,we report a single-dom...
This work was supported by the National Natural Science Foundation of China(Nos.22031003 and 21720102004);the Shanghai Science Technology Committee(No.19DZ2270100).
The construction of interlocked topologies by metal-cation-template methods has been extensively explored.However,construction of these species using template-free chemical self-assembly methods is hard to rationally ...
supported by the National Natural Science Foundation of China(key program 21890733)and the Shanghai Natural Science Foundation(no.18ZR1420800).
Catenated cages are generally considered thermodynamically more stable than their constituent monomeric cages.However,the catenation mechanism is yet to be elucidated;it would require systematic investigation into the...
We are grateful to acknowledge the National Basic Research Program(2013CB834502,2013CB834503);the National Natural Science Foundation of China(91527301,21434005,21525418,51773179,11302190,and 11432012);the Open Project of State Key Laboratory of Supramolecular Structure and Materials(sklssm201611)for financial support.
Mechanically interlocked molecules(MIMs)are prototypical molecular machines with parts that enable controlled,large-amplitude movement with one component positioned relative to another.Incorporating MIMs into polymeri...