THERMORESISTANCE

作品数:3被引量:1H指数:1
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相关期刊:《Bioactive Materials》《Chinese Chemical Letters》更多>>
相关基金:中国博士后科学基金国家自然科学基金更多>>
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Nanoplatform-based cellular reactive oxygen species regulation for enhanced oncotherapy and tumor resistance alleviation
《Chinese Chemical Letters》2023年第9期85-99,共15页Meifang Wang Ping’an Ma Jun Lin 
financially supported by the National Key Research and Development Program of China(No.2022YFB3804500);the National Natural Science Foundation of China(NSFC,Nos.51929201 and 52102354);the projects for Science and Technology Development Plan of Jilin province(Nos.20210402046GH and 20220508089RC)。
The cancer cells realize their proliferation and metastasis activities based on the special redox adaptation to increased reactive oxygen species(ROS)level,which inversely makes them sensitive to external interference...
关键词:Nanoagents ROS regulation ROS-mediated cancer therapy Multidrug resistance THERMORESISTANCE 
HDAC6 inhibitor loaded bimetallene nanosheets with antagonizing thermoresistance for augmented mild photothermal therapy
《Chinese Chemical Letters》2023年第9期235-242,共8页Lingyu Qiu Shan Lei Jing Zhang Ruhan Yan Wansi Chen Jing Lin Wei-Guo Zhu Peng Huang 
financially supported by National Key R&D Program of China(Nos.2020YFA0908800,2018YFA0704000);Basic Research Program of Shenzhen(Nos.JCYJ20200109105620482,JCYJ20180507182413022);Shenzhen Science and Technology Program(No.KQTD20190929172538530)。
Photothermal therapy(PTT)induces thermoresistance through cellular heat shock response,which impairs the therapeutic efficacy of the PTT.To resolve this problem,we developed a photothermal theranostics(denoted as PMH)...
关键词:Mild photothermal therapy THERMORESISTANCE Histone deacetylase 6 Heat shock proteins AUTOPHAGY 
2D antimonene-integrated composite nanomedicine for augmented low-temperature photonic tumor hyperthermia by reversing cell thermoresistance被引量:1
《Bioactive Materials》2022年第4期295-305,共11页Jianrong Wu Xiaojun Cai Gareth R.Williams Zheying Meng Weijuan Zou Li Yao Bing Hu Yu Chen Yuanyi Zheng 
the financial support from the NSFC Key Projects of International Cooperation and Exchanges(Grant No.81720108023);National Key R&D Program of China(Grant No.2018YFC0115200);National Natural Science Foundation of China(Grant No.82001943);Translational medicine national science and technology infrastructure(Shanghai)open project fund(TMSK-2020-004);China Postdoctoral Science Foundation(2020M681331,2021T140458).
The overexpression of heat shock proteins(HSPs)in tumor cells can activate inherent defense mechanisms during hyperthermia-based treatments,inducing thermoresistance and thus diminishing the treatment efficacy.Here,we...
关键词:Antimonene Heat shock proteins Photothermal therapy Glucose oxidase Calcium carbonate 
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