financially supported by the National Key Research and Development Program of China(No.2022YFB3804500);the National Natural Science Foundation of China(NSFC,Nos.51929201 and 52102354);the projects for Science and Technology Development Plan of Jilin province(Nos.20210402046GH and 20220508089RC)。
The cancer cells realize their proliferation and metastasis activities based on the special redox adaptation to increased reactive oxygen species(ROS)level,which inversely makes them sensitive to external interference...
financially supported by National Key R&D Program of China(Nos.2020YFA0908800,2018YFA0704000);Basic Research Program of Shenzhen(Nos.JCYJ20200109105620482,JCYJ20180507182413022);Shenzhen Science and Technology Program(No.KQTD20190929172538530)。
Photothermal therapy(PTT)induces thermoresistance through cellular heat shock response,which impairs the therapeutic efficacy of the PTT.To resolve this problem,we developed a photothermal theranostics(denoted as PMH)...
the financial support from the NSFC Key Projects of International Cooperation and Exchanges(Grant No.81720108023);National Key R&D Program of China(Grant No.2018YFC0115200);National Natural Science Foundation of China(Grant No.82001943);Translational medicine national science and technology infrastructure(Shanghai)open project fund(TMSK-2020-004);China Postdoctoral Science Foundation(2020M681331,2021T140458).
The overexpression of heat shock proteins(HSPs)in tumor cells can activate inherent defense mechanisms during hyperthermia-based treatments,inducing thermoresistance and thus diminishing the treatment efficacy.Here,we...