Aim Aging is the dominant risk factor for cardiovascular disease. Recently, we have shown that genom- ic instability, a causative mechanism of aging in general, induced by functional mutation of the ERCC1 DNA repair p...
In the last thirty years, it became obvious that the endothelium mediates relaxations of the underlying vas- cular smooth muscle cells by releasing endothelium-derived relaxing factors (EDtlF) , which results in end...