Background: Isotretinoin is widely used in the treatment of severe,recalcitrant,nodular acne.Mucocutaneous side-effects are seen in the great majority of patients and some of them have elevations in their serum lipid ...
Background Adverse changes in bone have been reported for patients undergoing high-dose, long-term (several years) isotretinoin therapy for disorders of cornification. The effect of short-term(4-5months)the rapyat the...