Background: St John s wort (SJW) is widely used as a treatment for depression. A phototoxic reaction, due to its content of hypericin, can occur in animals and in cell culture, and has been reported in humans. Hyper...
In most dermatology centres where phototesting is performed, the starting dose is calculated as a proportion of the minimal erythema dose (MED). Previous studies have found significant differences in MED readings betw...
Background:Recently the beneficial effect of excimer laser treatment has been reported for patients with vitiligo. The influence of treatment frequency on this effect is not clear. Objectives:To determine the optimal ...
UV radiation induces damage to human skin. Protection of skin by an oral photoprotective agent would have substantial benefits. We investigated the photoprotective effect of oral administration of an extract of the na...
Photopatch test (PhPT) interpretation is difficult and clinical relevance is n ot always apparent. A positive PhPT may reflect photocontact allergy or phototox icity. We hypothesized that it may also reflect the addit...
We have studied the cutaneous response to ultraviolet radiation, measured objectively as erythema in a sample of 12 body sites on 15 Northern European subjects with multiple doses of ultraviolet B (UVB). Skin pigmenta...