financially supported by the National Natural Science Foundation of China(U20A20299);Guangzhou Science and Technology Planning Project(202103000042);Guangdong Basic and Applied Basic Research Foundation(2019A1515011379);Guangdong Special Support Program(2017TX04N371);S&T Special Projects(SRPG22-020);Guangdong Enterprise Sci-tech Commissioner(GDKTP2020013400)。