supported by the National Natural Science Foundation of China(No.31570931 and No.31771002);the National Key Project for Research&Development of China(Grant no.2016YFA0502204).
Autoreactive CD8^(+)T cells,which play an indispensable role inβcell destruction,represent an emerging target for the prevention of type 1 diabetes(T1D).Altered peptide ligands(APLs)can efficiently induce antigen-spe...