the NIH CIPRA(No.1U19 A151915-03);the "973" National Key Project (No.G1999054107);the National Outstanding Youth Grant(No.39925030).
HIV-1 Nef protein plays an important role in HIV-1 pathogenesis, including downregulation of the cell surface CD4 and class I major histocompatibility complex (MHC), enhancement of virion infectivity and alteration ...
This study was funded by the National Nature Science Foundation of China (No. 30571641) and INCO: Phase 1/2 Clinical Testing of Clade C-based HIV-1 Candidate Vaccines in China (No. ICA4-2001-10148).
Background The correlation between HIV-1 Nef-specific CD8 T-cell responses and markers of HIV-1 disease progression still remains unclear. This study analysed and compared the role of HIV-1 Nef-specific CD8 T-cell res...