OLIGONUCLEOTIDE

作品数：101被引量：206H指数：7
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相关机构：北京大学首都医科大学南京医科大学中国科学院更多>>
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Virus-like supramolecular assemblies formed by cooperation of base pairing interaction and peptidic association
《Science China Chemistry》2016年第3期310-315,共6页Meiwen Cao Ningning Wang Peng Zhou Yawei Sun Jiqian Wang Shengjie Wang Hai Xu 
the National Natural Science Foundation of China (21473255, 21003160);the Fundamental Research Funds for the Central Universities (14CX05040A, 15CX05017A)
A peptide nucleic acid （PNA）-peptide conjugated molecule, T＇3（AKAE）2, was designed to have both a PNA segment for oligo- nucleotide binding and an ionic self-complementary peptide sequence for self-association. T...
关键词：peptide nucleic acid OLIGONUCLEOTIDE artificial virus co-assembly supramolecular complex 
A new quantitative structure-retention relationship model for predicting chromatographic retention time of oligonucleotides被引量：2
《Science China Chemistry》2011年第7期1064-1071,共8页ZHAO Wei LIANG GuiZhao CHEN YuZhen YANG Li 
supported by the National Natural Science Foundation of China (10901169);National 111 Programme of Introducing Talents of Discipline to Universities (0507111106);Innovation Ability Training Foundation of Chongqing University (CDCX008);Innovative Group Program for Graduates of Chongqing University,Science;Innovation Fund (200711C1A0010260)
An integrated approach is proposed to predict the chromatographic retention time of oligonucleotides based on quantitative structure-retention relationships （QSRR） models. First, the primary base sequences of oligon...
关键词：OLIGONUCLEOTIDE quantitative structure-retention relationship scores of generalized base properties auto cross covariance genetic algorithm support vector machine 
In situ synthesis of DNA micro-arrays using typography technique
《Science China Chemistry》2007年第1期75-83,共9页TANG JianXin 1,2 ,HE NongYue 1,2,3 &LI Song 1 1State Key Laboratory of Bioelectronics,Southeast University,Nanjing 210096,China 2Key Laboratory of Green Packaging and Application of Biological Nanotechnology of Hunan Province,Hunan University of Tech- nology,Zhuzhou 412008,China 3Zhongshan Huoju Polytechnic,Zhongshan 528436,China 
the National Natural Science Foundation of China(Grant Nos.60571032,60571001,90606027 and 60121101);National Hi-Tech Research andDevelopment Program of China(Grant No.2006AA03Z357);Natural ScienceFoundation of Hunan Province(Grant Nos.04jj40023 and 06JJ4012);the NaturalScience Foundation of Guangdong Province(Grant No.04008782)
A novel typography technique was developed to in situ synthesize oligonucleotide arrays on glass slide,which has the celerity,high spatial resolution,lower cost,reliable operation,and high synthetic efficiency.The pri...
关键词：TYPOGRAPHY OLIGONUCLEOTIDE in SITU synthesis DNA microarrays 
DNA microarray synthesis by using PDMS molecular stamp (Ⅱ)——Oligonucleotide on-chip synthesis using PDMS stamp被引量：3
《Science China Chemistry》2001年第4期442-448,共7页肖鹏峰 何农跃 贺全国 张春秀 王轶文 陆祖宏 徐吉庆 
Acknowledgements This work was supported by the National 863 High-Tech Project, 973 National Key Fundamental Research Project and the National Natural Science Foundation of China (Grant No. 60071001).
Based on the standard phosphoramidites chemistry protocol, two oligonucleotides synthetic routes were studied by contact stamping reactants to a modified glass slide. Route A was a contact coupling reaction, in which ...
关键词：PDMS stamps contact coupling contact detritylation oligonucleotide synthesis. 
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