OLIGONUCLEOTIDES

作品数：75被引量：205H指数：6
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相关作者：王晶刘张岚高运华张玲张礼和更多>>
相关机构：北京大学中国计量科学研究院湖南医科大学北京大学第一医院更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>
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Inhibition of human prostate cancer xenograft growth by 125I labeled triple-helin forming oligonucleotide directed against androgen receptor被引量：6
《Chinese Medical Journal》2008年第22期2284-2289,共6页ZHANG Yong MA Yi LU Han-ping GAO Jin-hui LIANG Chang-sheng LIU Chang-zheng ZOU Jun-tao WANG Hua-qiao 
This study was supported by a grant from the Natural Science Foundation of Guangdong Province, China （No. 5001697）.
Background The failure of hormone treatment for advanced prostate cancer might be related to aberrant activation of the androgen receptor. We have shown that 125I labeled triple-helix forming oligonucleotide （TFO） a...
关键词：prostate cancer androgen receptor OLIGONUCLEOTIDES iodine radioisotopes gene therapy 
Apoptosis of drug-resistant human ovarian carcinoma cell line COCl/DDP induced by survivin antisense oligonucleotides被引量：1
《Chinese Medical Journal》2006年第18期1572-1575,共4页ZHENG Fei RUAN Fei XIE Xian-kuan LIU Shao-yang 
Currently, surgery-oriented treatment plays a major role in the treatment of ovarian cancer patients. But 5-year survival rate of patients is still around 30%. One of the main reasons for the low survival rate is the ...
关键词：ovarian carcinoma oligonucleotides  antisense APOPTOSIS 
Combination and cleavage of HBV DNA fragments by triple helix-forming oligonucleotides modified with manganese porphyrin in vitro被引量：1
《Chinese Medical Journal》2003年第8期1248-1252,共5页光丽霞 袁发焕 奚敏 赵聪敏 刘立 温恩懿 艾友萍 
ThisstudywassupportedbyagrantfromtheNationalNaturalScienceFoundationofChina (No 3 980 0 12 8)
Objective To observe the ability of triple helix-forming oligonucleotides (TFOs) modified with manganese porphyrin to combine with and cleave HBV DNA fractions. Methods TFO were modified with manganese porphyrin and...
关键词：oligodeoxyribonucleotides·hepatitis B virus·manganese·porphyrins·acridines 
Renal cell carcinoma related novel gene, GYLZ-RCC18: cloning and functional studies
《Chinese Medical Journal》2002年第5期746-749,155-156,共4页张强 梁丽莉 席志军 丁义 佟明 张志文 郭应禄 李钟 陈琳 
ThisprojectwassupportedbyagrantfromtheNationalNaturalScienceFoundationofChina (No 3 9870 841)
OBJECTIVE: To clone the full length of renal cell carcinoma (RCC) related novel gene GYLZ-RCC18 and study its function. METHODS: SMART RACE technology was used to clone the full length of GYLZ-RCC18. RT-PCR was used t...
关键词：Apoptosis Carcinoma  Renal Cell Cell Division Cell Line Cloning  Molecular DNA  Antisense DNA  Complementary Gene Expression Regulation  Neoplastic Genes  Neoplasm Humans Kidney Neoplasms Neoplasm Proteins OLIGONUCLEOTIDES Research Support  Non-U.S. Gov't Sequence Analysis  DNA Transfection Tumor Cells  Cultured 
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