OXA

作品数:155被引量:369H指数:10
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相关领域:医药卫生更多>>
相关作者:张晓丽张守发贾立军刘明明范学财更多>>
相关机构:延边大学郑州大学佳木斯大学附属第一医院中国科学院更多>>
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安寐丹“生熟枣仁”同用及拆方调控Orexin信号通路改善失眠大鼠模型突触可塑性的差异及机制探究
《世界科学技术-中医药现代化》2024年第12期3218-3233,共16页徐波 孙康 王平 谢光璟 叶子靖 秦庆花 夏婧 
国家自然科学基金委员会青年项目(82104712):培元固本安神法调控Orexin信号通路改善睡眠剥夺模型大鼠学习记忆的分子机制研究,负责人:徐波;国家自然科学基金委员会青年项目(82205232):从“昼精夜瞑”角度探讨枣仁生熟同用激活MAPK/MNK/eIF4E通路调控老年模型睡眠-觉醒节律的作用机制,负责人:夏婧。
目的基于食欲素(Orexin)信号通路调控的突触可塑性初步探索清代经典名方安寐丹“生熟枣仁”同用及拆方对失眠大鼠模型学习记忆的影响差异及可能机制。方法腹腔注射对氯苯丙氨酸(PCPA)构建失眠大鼠模型,给予安寐丹“生熟枣仁”同用及拆...
关键词:安寐丹 失眠 学习记忆 突触可塑性 OXA/PLC_(β-1)/PKC_(α)/ERK_(1/2)信号通路 
Alkynol-Supported New Cascade Strategy for Eco-Friendly Conversion of CO_(2)into 1,3-Oxazinan-2-ones Catalyzed by Strong-Acid/Base-Resistant Metal-Organic Framework
《CCS Chemistry》2024年第12期2982-2995,共14页Xiang-Shuai Li Jian Zhao Sheng-Li Hou Hang Xu Ze-Long Liang Ying Shi Bin Zhao 
supported by the National Natural Science Foundation of China(grant nos.92161202,21971125,21625103,22101138,22206088,and 22121005);the China Postdoctoral Science Foundation(grant no.2023M741815).
The conversion of carbon dioxide(CO_(2))into 1,3-oxazinan-2-ones has attracted increasing attention owing to the latter’s potential for curing various diseases.However,current strategies for the conversion have low e...
关键词:1 3-oxazinan-2-one CO_(2)conversion heterogeneous catalysis metal-organic frameworks three-component reaction 
Preclinical Evaluation of the Antidiabetic Effect and Phytochemical HPLC-MS ESI-QTOF Analysis of Sclerocarya birrea (A. Rich) Hoscht Bark of Trunk Aqueous Extract in Alloxan-Induced Diabetic Wistar Rat
《Pharmacology & Pharmacy》2024年第11期364-387,共24页Ida Valerie Yasmina Ga San Nintie Traoré Lazare Belemnaba Windingoudi Rimwagna Christian Ouedraogo Boukaré Kaboré Rémy Kindanloun Bationo Bonéwendé Mohamed Belemlilga Souleymane Compaoré Wendinmi Bertrand Florent Goumbri Salfo Ouedraogo Moumouni Koala Mathieu Nitiéma 
Introduction: Diabetes is a serious public health problem requiring complex treatment. Numerous ethnopharmacological studies have reported the traditional use of Sclerocarya birrea in managing diabetic patients. This ...
关键词:Preclinical Study Sclerocarya birrea Antidiabetic Effect ALLOXAN HPLC-MS 
碳青霉烯类和喹诺酮类双重耐药核酸胶体金试纸条快速检测方法的建立及试剂盒研制
《中国免疫学杂志》2024年第11期2386-2390,2398,共6页潘蓓珍 杨继飞 王岳峰 刘岩 周钰娇 马玉贺 孙丽媛 
吉林省科技发展计划项目(20230204085YY);北华大学研究生创新计划项目([2022]027)。
目的:建立双重核酸胶体金试纸条快速检测鲍曼不动杆菌(Ab)OXA和par C耐药基因的方法并研制试剂盒。方法:采用加热煮沸法提取Ab的DNA,根据NCBI选择Ab的OXA和par C基因序列作为靶基因片段,设计引物并分别用6-FAM、地高辛和生物素进行标记...
关键词:鲍曼不动杆菌 OXA par C 分子克隆 胶体金 核酸试纸条 
One-pot synthesis of a giant twisted double-layer chiral macrocycle via [4+8] imine condensation and its X-ray structure
《Chinese Chemical Letters》2024年第10期241-243,共3页Yu Pang Min Wang Ning-Hua Yang Min Xue Yong Yang 
supported by the National Natural Science Foundation of China(Nos.21971223 and 21772178)。
Trifluoroacetic acid(TFA)catalyzed condensation reaction between tetraaminooxacalix[4]arene and N-alkylcarbazole-3,6-dicarbaldehyde in CH_(2)Cl2afforded a single product in 87%–89%yield.Well-defined yet undissolvable...
关键词:One-pot synthesis arene Dynamic covalent chemistry Chiral macrocycle X-ray single crystal 
Enantioselective Synthesis,(Chir)optical Properties,and Postsynthetic Functionalization of Furan-Containing Oxa[5]-,Oxa[6]-,and Dioxa[6]helicenes
《CCS Chemistry》2024年第10期2439-2451,共13页Wei Fu Valentina Pelliccioli Raquel Casares-López Juan M.Cuerva Martin Simon Christopher Golz Manuel Alcarazo 
the Deutsche Forschungsgemeinschaft(INST 186/1352-1 and INST 186/1237-1)is gratefully acknowledged.W.F;thanks the China Scholarship Council for PhD fellowship support.R.C.-L.gratefully acknowledges grant PID2021-127964NB-C22 funded by the MCIN/AEI/10.13039/501100011033.
An expedient synthesis of a series of configurationally stable oxa[5]helicenes,oxa[6]helicenes,and dioxa[6]helicenes has been developed using an intramolecular,highly enantioselective,Au-catalyzed,alkyne hydroarylatio...
关键词:Au-catalysis enantioselective synthesis oxa[n]helicenes racemization dynamics postsynthetic functionalization 
国际动态
《建筑玻璃与工业玻璃》2024年第6期37-41,共5页秦子川(译) 
AIS与INOXAP签署绿氢供应协议印度领先的玻璃制造商AGC印度玻璃公司(AIS)与印度最大的工业和医疗气体制造商INOXAP签署了一项为期20年的承售协议,后者将为AIS公司位于印度拉贾斯坦邦Chittorgarh Soniyana的新建浮法玻璃工厂供应绿色氢能。
关键词:拉贾斯坦邦 浮法玻璃 AIS 制造商 供应协议 OXA 印度 
疏肝健脾养心方对失眠模型小鼠食欲素A及其受体的干预作用被引量:3
《中国实验方剂学杂志》2024年第10期54-61,共8页王震 张杰 刘飞祥 孙江燕 高亚慧 郑育新 赵敏 
国家中医药传承创新专项(2022JDZX004,2022CCCX008)。
目的:探讨疏肝健脾养心方下调食欲素A(OXA)及食欲素受体1(OX1R)、食欲素受体2(OX2R)的表达对失眠模型小鼠的干预作用。方法:利用腹腔注射对氯苯丙氨酸(PCPA)建立失眠小鼠模型,50只BALB/c小鼠随机分为空白组、模型组、右佐匹克隆组(0.13...
关键词:疏肝健脾养心方 失眠 食欲素A(OXA) 5-羟色胺(5-HT) 
Synthesis of energetic coordination polymers based on 4-nitropyrazole by solid-melt crystallization in non-ionization condition
《Defence Technology(防务技术)》2023年第10期13-22,共10页Ting-wei Wang Shu Bu Kun Wang Lu Zhang Zhen-xin Yi Shun-guan Zhu Jian-guo Zhang 
the projects of National Natural Science Foundation of China(Grant Nos.22175025 and 21905023)for their generous financial support.
Based on the theory of crystallization,a solvent-free solid-liquid phase crystallization method called solid-melt crystallization was designed to prepare energetic coordination polymers.Two target compounds[Cu(NPyz)_(...
关键词:4-Amino-1 2 5-oxadiazole-3-carbohydrazide Crystallization Coordination polymers Laser Primary explosives 
Phenylethanoid glycosides from traditional Mongolian medicine Cymbaria daurica alleviate alloxan-induced INS-1 cells oxidative stress and apoptosis被引量:2
《Food Science and Human Wellness》2023年第5期1580-1589,共10页Ruyu Shi Xing Li Bing Gao Chunhong Zhang Minhui Li 
funded by the National Natural Science Foundation of China (81760776);the Natural Science Foundation of Inner Mongolia Autonomous Region (2018ZD13);the Natural Science Foundation of Inner Mongolia Autonomous Region (2020MS08070);Science and technology development projects in key areas of Baotou science and technology plan (2020Z1016-3);Natural Science Foundation Project of Inner Mongolia Autonomous Region (2021MS03025)。
Cymbaria daurica L. is a well-known traditional Mongolian medicine, which has been used to treat diabetesrelated conditions characterized by persistent thirst and hunger, copious urination, and weight loss. We aimed t...
关键词:Diabetes mellitus Cymbaria daurica L. Phenylethanoid glycosides Alloxan-induced cell injury 
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