ALLOXAN

作品数:51被引量:128H指数:6
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相关领域:医药卫生更多>>
相关作者:姜正二郑里翔朱敏英李爱冬梅妍更多>>
相关机构:四川大学延边大学江西中医药大学湖北民族大学更多>>
相关期刊:《Journal of Diabetes Mellitus》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《四川解剖学杂志》更多>>
相关基金:国家自然科学基金浙江省医药卫生科学研究基金更多>>
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Preclinical Evaluation of the Antidiabetic Effect and Phytochemical HPLC-MS ESI-QTOF Analysis of Sclerocarya birrea (A. Rich) Hoscht Bark of Trunk Aqueous Extract in Alloxan-Induced Diabetic Wistar Rat
《Pharmacology & Pharmacy》2024年第11期364-387,共24页Ida Valerie Yasmina Ga San Nintie Traoré Lazare Belemnaba Windingoudi Rimwagna Christian Ouedraogo Boukaré Kaboré Rémy Kindanloun Bationo Bonéwendé Mohamed Belemlilga Souleymane Compaoré Wendinmi Bertrand Florent Goumbri Salfo Ouedraogo Moumouni Koala Mathieu Nitiéma 
Introduction: Diabetes is a serious public health problem requiring complex treatment. Numerous ethnopharmacological studies have reported the traditional use of Sclerocarya birrea in managing diabetic patients. This ...
关键词:Preclinical Study Sclerocarya birrea Antidiabetic Effect ALLOXAN HPLC-MS 
Methods to Reduce the Hypoglycemic Mortality of Alloxan in Diabetic Rabbit Model
《Journal of Biosciences and Medicines》2024年第5期242-255,共14页Changtai Luo Dong Luo Luchang Chen Haidong Zhou Ruiqi Zhou Jihua Wei 
Objective: To explore an intervention method to reduce the mortality of alloxan diabetes model, and to preliminarily analyze the mechanism of alloxan induced animal death. Methods: Healthy New Zealand rabbits were ran...
关键词:ALLOXAN DIABETES Model RABBIT 
Effect of Tetracera potatoria Aqueous Extract on Mellitus Diabetes and Its Complication Preventions in Wistar Rats
《Journal of Biosciences and Medicines》2023年第7期207-222,共16页Dhornycia Euroldyne Malaissou Tony Raoul Ampa Abraham Mayoke Roger Pavel Boukongo Hono Mavie Mambeke Berthrand Stéphane Lingomo Wossolo Martin Diatewa 
Background: Diabetes is becoming a serious public health issue with expensive treatment that is less accessible to all patients in least developing countries. The traditional African pharmacopoeia offers accessible an...
关键词:Mellitus Diabetes Tetracera potatoria Aqueous Extract ALLOXAN 
Hydro-Ethanol Extract of Persea americana Fruit Pulp Ameliorates Dyslipidaemia and Cardiotoxicity Exerted by Alloxan-Induced Diabetes Mellitus
《Journal of Biosciences and Medicines》2022年第12期201-216,共16页Bernard Omokheshi Adele Chidi Okonkwo Anthony Olusoji Odetola Idara Emmanuel Emediong Abayomi Oluwatosin Ige Elsie Olufunke Adewoye 
Diabetes-induced dyslipidaemia has been associated with an increased risk of atherosclerosis and coronary heart diseases. Persea americana fruit has been reported to possess anti-diabetic properties. Therefore, this s...
关键词:Persea americana Diabetes Mellitus Dyslipidaemia and Alloxan 
Antidiabetic Potential of Carthamus oxycantha M.Bieb. Seeds in Alloxan Induced Diabetic Rats
《Pharmacology & Pharmacy》2022年第6期189-198,共10页Ali Imran Abid Hira Muzammel Humera Shafi Mouqadus Un Nisa Hassan Ali Muhammad Waqar Afzal Nadeem UL Hassan Khan Fahad Muzammil 
Ethnopharmacological Relevance: Diabetes Mellitus is one of the most common disorders of metabolic abnormalities. It is characterized by hyperglycemia followed by abnormalities in insulin release, insulin work, or bot...
关键词:Diabetes Mellitus Carthamus oxycantha ALLOXAN GLIBENCLAMIDE AEECO 
In <i>Vivo</i>Hypoglycemic Activity of Aqueous Extracts of <i>Chasmanthera dependens</i>in Alloxan Induced Diabetic Mice
《Open Journal of Applied Sciences》2021年第7期832-845,共14页Dinah J. Sawe Eliud N. M. Njagi Alice N. Muchugi Moses Ndiema 
The plant Chasmanthera dependens (Hochst) have been used to manage many diseases including diabetes mellitus without scientific evaluation of its efficacy and safety. The main objective of the project was to de...
关键词:DIABETES HYPOGLYCEMIA Plant Extract Chasmanthera dependens Albino Mice 
Effect of Doum Fruit (Hyphaene Thebaica) Extract on Some Biochemical Parameters, Enzyme Activities and Histopathological Changes of Pancreas in Alloxan Induced Diabetic Rats
《Food and Nutrition Sciences》2020年第3期207-219,共13页Naglaa Abd Fattah Abd el Halim Hassan 
Medicinal plants have been used in the treatment of some diseases like diabetes. One of them is doum fruit extract. The study was conducted to evaluate effect of doum fruit extract on some biochemical parameters, incl...
关键词:Doum FRUIT EXTRACT ALLOXAN HISTOPATHOLOGICAL MDA Biochemical Parameters 
Improvement of Dissolution Rate of Gliclazide Using Solid Dispersions with Aerosil 380 and Its Effect on Alloxan Induced Diabetic Rats被引量:2
《Pharmacology & Pharmacy》2019年第8期365-385,共21页Subrata Paul Md. Nur Islam Md. Ashraf Ali Ranjan Kumar Barman Mir Imam Ibne Wahed Bytul M. Rahman 
The main objective of this research is to conduct a comprehensive study for enhancing the aqueous solubility of poorly water soluble gliclazide using hydrophilic fumed silica particles (Aerosil®380) and evaluatin...
关键词:In-Vitro DISSOLUTION Fumed Silica Solid DISPERSIONS GLICLAZIDE ALLOXAN DIABETES 
不同剂量四氧嘧啶(Alloxan)对制备糖尿病小鼠模型的影响因素分析被引量:3
《吉林医学》2019年第3期447-449,共3页朱金羽 向星炜 张景昊 姜正二 
目的:探讨四氧嘧啶(Alloxan)的不同剂量和不同给药途径诱导制备糖尿病小鼠模型的影响因素。方法:选用雄性昆明种小鼠110只,体重为18~26 g,分为五个试验组,其中静脉注射组50只分为小、大剂量(60 mg/kg·bw、80 mg/kg·bw)两个组,同样腹...
关键词:四氧嘧啶 小鼠糖尿病模型 影响因素 
Pathological changes in the cellular structures of retina and choroidea in the early stages of alloxan-induced diabetes被引量:6
《World Journal of Diabetes》2018年第12期239-251,共13页Irina Danilova Svetlana Medvedeva Svetlana Shmakova Margarita Chereshneva Alexey Sarapultsev Petr Sarapultsev 
Supported by the Russian Science Foundation,No.16-15-00039
AIM To investigate the temporal sequence of pathological changes in the cellular structures of retina and choroidea in the early stages of diabetes in laboratory animals.METHODS Experimental type 1 diabetes was modele...
关键词:ALLOXAN DIABETES DIABETIC RETINOPATHY Early stage Morphology HISTOLOGICAL changes 
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