GLICLAZIDE

作品数：19被引量：44H指数：3
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相关领域：医药卫生更多>>
相关作者：杨志宏王维力于德民梁劲松王家驰更多>>
相关机构：天津医学院天津医科大学天津大学更多>>
相关期刊：《Journal of Pharmaceutical Analysis》《American Journal of Analytical Chemistry》《Science China(Life Sciences)》《Acta Pharmacologica Sinica》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>
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Comparison of gliclazide vs linagliptin on hypoglycemia and cardiovascular events in type 2 diabetes mellitus: A systematic review被引量：2
《World Journal of Diabetes》2022年第12期1168-1183,共16页Viswanathan Mohan Subhash Wangnoo Sambit Das Rajnish Dhediya Kumar Gaurav 
BACKGROUND Cardiovascular outcome trials have demonstrated cardiovascular safety of glimepiride(a sulfonylureas) against dipeptidyl peptidase-4 inhibitor linagliptin.Gliclazide(another newer sulfonylureas) has shown s...
关键词：LINAGLIPTIN GLICLAZIDE HYPOGLYCEMIA Major cardiovascular adverse events Type 2 diabetes 
Formulation Development and Evaluation of Poorly Water Soluble Gliclazide Tablet Containing Aerosil 380 as Carrier
《Pharmacology & Pharmacy》2019年第9期396-405,共10页Mir Rashed Ali Kaniz Fatema Asha Subrata Paul Bytul M. Rahman 
The core objective of the current work was to improve dissolution rate of poorly water-soluble anti-diabetic drug gliclazide by solid dispersions (SDs) technique using fumed silica particles Aerosil 380 as carrier int...
关键词：Solid DISPERSIONS GLICLAZIDE AEROSIL 380 TABLET DISSOLUTION Profile 
Improvement of Dissolution Rate of Gliclazide Using Solid Dispersions with Aerosil 380 and Its Effect on Alloxan Induced Diabetic Rats被引量：2
《Pharmacology & Pharmacy》2019年第8期365-385,共21页Subrata Paul Md. Nur Islam Md. Ashraf Ali Ranjan Kumar Barman Mir Imam Ibne Wahed Bytul M. Rahman 
The main objective of this research is to conduct a comprehensive study for enhancing the aqueous solubility of poorly water soluble gliclazide using hydrophilic fumed silica particles (Aerosil®380) and evaluatin...
关键词：In-Vitro DISSOLUTION Fumed Silica Solid DISPERSIONS GLICLAZIDE ALLOXAN DIABETES 
Studies on Cardiac Cytoarchitectonic and Biochemical Indices in Pregnant Streptozotocin-lnduced Diabetic Rats Treated with Gliclazide and Insulin
《Journal of Pharmacy and Pharmacology》2018年第1期38-51,共14页Olojede Samuel Oluwaseun Lawal Sodiq Kolawole Medubi Leke Jacob Adekoya Abimbola Julius Esubi Juan Uche Dauda Feyikemi Funmilayo Buhari Muhammed Olanrewaju Osinubi Abraham Adewale 
Introduction： GDM （gestational diabetes mellitus） is a common complication of pregnancy, and prevalence has become alarming. Insulin remains the cornerstone in management of diabetes mellitus but oral agents have b...
关键词：GLICLAZIDE Gestational diabetes mellitus INSULIN CARDIOMYOCYTES oxidative stress. 
Waist Circumference-dependent Peripheral Monocytes Change after Gliclazide Treatment for Chinese Type 2 Diabetic Patients被引量：1
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2017年第2期204-209,共6页李青 于浩泳 陈淼 江枫 周健 包玉倩 胡承 贾伟平 
973 Program(No.2011CB504001);the National Natural Science Foundation of China(Nos.81322010,81170735 and 81200582);the Drug Innovation Program of the National Science and Technology Project(No.2011ZX09307-001-02);863 Program(No.2012AA02A509);Excellent Young Medical Expert of Shanghai(No.XYQ2011041);Shanghai Talent Development Grant(No.2012041);National Young Top Talent Supporting Program
Gliclazide used for the treatment of type 2 diabetes mellitus（T2DM） stimulates insulin secretion and influences peripheral blood monocytes.The roles of gliclazide in peripheral monocytes of newly diagnosed T2 DM pat...
关键词：gliclazide monocytes waist type 2 diabetes obesity 
Efficacy and safety of metformin and sitagliptin based triple antihyperglycemic therapy(STRATEGY):a multicenter,randomized,controlled,non-inferiority clinical trial被引量：20
《Science China(Life Sciences)》2017年第3期225-238,共14页Wen Xu Yiming Mu Jiajun Zhao Dalong Zhu Qiuhe Ji Zhiguang Zhou Bin Yao Anhua Mao Samuel S.Engel Bin Zhao Yan Bi Longyi Zeng Xingwu Ran Juming Lu Linong Ji Wenying Yang Weiping Jia Jianping Weng 
supported by Merck&Co.,Inc.,Kenilworth,NJ,the 5010 Project of Sun Yat-sen University;Program for Changjiang Scholars and Innovative Research Team in University(to Jianping Weng)
Despite the current guideline's recommendation of a timely stepwise intensification therapy,the "clinical inertia",termed as the delayed treatment intensification,commonly exists in the real world,which may be partly ...
关键词：type 2 diabetes oral antihyperglycemic agent metformin DPP-4 inhibitor glimepiride gliclazide repaglinide acarbose 
Comparison of the Hypoglycemic, Hypolipidemic and Hepatoprotective Effects of<i>Asparagus racemosus</i>Linn. in Combination with Gliclazide and Pioglitazone on Alloxan-Induced Diabetic Rats被引量：1
《Pharmacology & Pharmacy》2017年第2期52-74,共23页Abdullah Al Mamun Mahbubul Hossain Md.Sahab Uddin Md.Tanjir Islam Sajjad Hossain Md.Sarwar Hossain Md.Farhad Hossain Ataur Rahman Sujan Mamunur Rashid Md.Mahbubur Rahman A.F.M.Towheedur Rahman 
In recent years, the popularity of medicinal plants as a remedy has been increased manifold due to having minimal adverse effects. The current study aimed to compare the hypoglycemic, hypolipidemic and hepatoprotectiv...
关键词：Diabetes Mellitus Asparagus racemosus GLICLAZIDE PIOGLITAZONE COMBINATION Therapy 
Polymorphisms of the KCNQ1 gene are associated with the therapeutic responses of sulfonylureas in Chinese patients with type 2 diabetes被引量：4
《Acta Pharmacologica Sinica》2017年第1期80-89,共10页Qing LI Ting-ting TANG Feng JIANG Rong ZHANG Miao CHEN Jun YIN Yu-qian BAO Xiang CHENG Cheng HU Wei-ping JIA 
KCNQ1 channel is a member of the voltage-gated potassium channel KQT-like subfamily. The KCNQ1 gene has recently been identified as a susceptibility locus for type 2 diabetes mellitus （T2DM）. In the present study, w...
关键词：potassium channel KCNQ1 type 2 diabetes SULFONYLUREAS gliclazide MR PHARMACOGENETICS 
Formulation and <i>In-Vitro</i>Release Pattern Study of Gliclazide Matrix Tablet
《Pharmacology & Pharmacy》2015年第3期125-131,共7页Tanbir Ahammad Marium Begum A. F. M. Towheedur Rahman Moynul Hasan Saikat Ranjan Paul Shaila Eamen Md. Iftekhar Hussain Md. Hazrat Ali Md. Ashraful Islam Mohammad Mizanur Rahman Mamunur Rashid 
In current decade, pharmaceutical industries of Bangladesh are giving much emphasize on the formulation of time release preparation to treat various chronic diseases in order to decrease the frequency of administratio...
关键词：GLICLAZIDE Sustained RELEASE Methocel K15M CR Methocel K4M CR In-Vitro BIOEQUIVALENCE 
Formulation and characterization of extruded and spheronized pellets using pectin and crosslinking agents
《Journal of Chinese Pharmaceutical Sciences》2014年第11期790-798,共9页Pallavi M.Chaudhari Pravin D.Chaudhari 
The aim of this study was to prepare pellets of gliclazide by extrusion spheronization process by use of two methods in situ cross linking method and interfacial complexation method and to study the effect of differen...
关键词：EXTRUSION-SPHERONIZATION GLICLAZIDE PELLETS PECTIN Anti-diabetic activity 
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