PIOGLITAZONE

作品数:75被引量:340H指数:10
导出分析报告
相关领域:医药卫生更多>>
相关作者:钟妤张新华温进坤孙艳魏超更多>>
相关机构:河北医科大学广西医科大学第一附属医院苏州大学中南大学更多>>
相关期刊:更多>>
相关基金:国家自然科学基金国家教育部博士点基金安徽省自然科学基金重庆市自然科学基金更多>>
-

检索结果分析

结果分析中...
条 记 录,以下是1-10
视图:
排序:
PPARγ激动剂Pioglitazone对神经病理性疼痛大鼠小胶质细胞线粒体氧化应激的影响
《广西医科大学学报》2024年第2期233-240,共8页凌国栩 黄彤虹 许庆龄 赵雪媚 朱秋霖 钟妤 谢玉波 
广西自然科学基金面上项目(No.2023GXNSFAA026076);国家自然科学基金资助项目(No.81373498;No.81560500)。
目的:探讨过氧化物酶体增殖物激活受体-γ(PPARγ)激动剂吡格列酮(Pioglitazone)对神经病理性疼痛大鼠痛行为学及对脊髓背角小胶质细胞线粒体氧化应激的影响。方法:将40只SD雄性大鼠按随机数字表法分为4组:假手术(sham)+溶剂二甲基亚砜...
关键词:神经病理性疼痛 小胶质细胞 线粒体 氧化应激 炎症 
Interaction between OCT1 and LPIN1 polymorphisms and response to pioglitazone-metformin tablets in patients with polycystic ovary syndrome
《Chinese Medical Journal》2023年第14期1756-1758,共3页Haixia Zeng Yanting Huang Dengke Liu Tianqin Xie Zheng Chen Qiulan Huang Xiaojun Zhou Xiaoyang Lai Jianping Liu 
To the Editor:Polycystic ovary syndrome(PCOS)is a common endocrine disorder among women of reproductive age.PCOS is characterized by infrequent or absent ovulation,high androgen levels,and hyperinsulinaemia.Androgenic...
关键词:TABLETS AZONE DRUGS 
Neuron stem cell NLRP6 sustains hippocampal neurogenesis to resist stress-induced depression被引量:6
《Acta Pharmaceutica Sinica B》2023年第5期2017-2038,共22页Chuanfeng Tang Qiaona Wang Jingyan Shen Congying Wang Hong Ding Shiyu Wen Fan Yang Ruiqing Jiao Xingxin Wu Jianmei Li Lingdong Kong 
National Key R&D Program of China(2022YFC3500303);National Natural Science Foundation of China(81991522);partly by the Open Project of State Key Laboratory of Natural Medicine,No.SKLNMKF202204,China。
Neurogenesis decline in hippocampal dentate gyrus(DG)participates in stress-induced depressive-like behaviors,but the underlying mechanism remains poorly understood.Here,we observed low-expression of NOD-like receptor...
关键词:NLRP6 Neural stem cells Stress resilience Depressive-like behaviors ECRG4 Mitochondrial function PROLIFERATION PIOGLITAZONE 
鞘内注射PPARγ激动剂Pioglitazone对神经病理性疼痛大鼠痛行为及星形胶质细胞活性的影响
《医学信息》2023年第7期85-89,共5页黄彤虹 凌国栩 钟妤 
广西自然科学基金项目(编号:2015GXNSFAA139154、2017GXNSFBA198039)。
目的观察鞘内注射PPARγ激动剂Pioglitazone对神经病理性疼痛大鼠痛行为及星形胶质细胞活性的影响。方法将220~250 g的雄性SPF级SD大鼠64只按随机数字表法分为4组:Sham+DMSO组(二甲基亚砜,S+D组)、Sham+Pioglitazone组(S+P组)、CCI+DMSO...
关键词:神经病理性疼痛 过氧化物酶体增殖物激活受体Γ 星形胶质细胞 胶质纤维酸性蛋白 炎性因子 
Treatment and five-year follow-up of type A insulin resistance syndrome:A case report被引量:1
《World Journal of Clinical Cases》2022年第8期2522-2528,共7页Yong-Hua Chen Qing-Qing Chen Chun-Lin Wang 
BACKGROUND Type A insulin resistance syndrome(TAIRS)is a rare disorder characterized by severe insulin resistance due to defects in insulin receptor signaling.No specific drugs are available for the treatment of TAIRS...
关键词:Type A insulin resistance syndrome TREATMENT PIOGLITAZONE FLUTAMIDE Case report 
A pharmacological study of pioglitazone in the regulation of adipocyte differentiation
《Journal of Chinese Pharmaceutical Sciences》2022年第3期176-183,共8页Chuan Qin Qi Wan Lei Xi Mian Wei Quan Du 
National Natural Science Foundation of China(Grant No.3207040249).
As a pathological result of the abnormal differentiation of adipocytes,the occurrence of obesity will not only lead to weight gain,abnormal energy metabolism,but also the development of the diseases such as diabetes.E...
关键词:Long non-coding RNA Adipocyte differentiation PIOGLITAZONE slincRAD 
Comparative Review of Drugs Used in Diabetes Mellitus—New and Old
《Journal of Diabetes Mellitus》2021年第4期115-131,共17页Furqan Ul Haq Abuzar Siraj Muhammad Atif Ameer Tanveer Hamid Mansoor Rahman Salman Khan Saad Khan Sarwat Masud 
Background: Diabetes mellitus (DM) is a syndrome of chronically elevated glucose level in the blood either due to insulin resistance, insulin deficiency or both. In addition, it may occur due to defec...
关键词:Anti-Diabetic Drugs METFORMIN SITAGLIPTIN Canagliflozin EXENATIDE PIOGLITAZONE Insulin Use and Its Efficacy GLIPIZIDE 
Diabetes and NAFLD:a high-risk cohort with definite therapeutic potential
《Hepatoma Research》2020年第12期1-11,共11页Lucia Brodosi Alessandra Musio Francesca Alessandra Barbanti Dorina Mita Giulio Marchesini Maria Letizia Petroni 
Barbanti FA is supported by a contract financed by Italian Ministry of Health and Italian Regions(NET-2016-02364191).
Despite the fact that non-alcoholic fatty liver disease(NAFLD)and its severe clinical forms[non-alcoholic steatohepatitis(NASH)and NASH-cirrhosis]are highly prevalent in the general population,there are no licensed dr...
关键词:METFORMIN PIOGLITAZONE INCRETINS DPP-4 inhibitors GLP-1 receptor agonists SGLT-2 inhibitors insulin cirrhosis 
Pioglitazone ameliorates neuronal damage after traumatic brain injury via the PPARg/NF-kB/IL-6 signaling pathway被引量:10
《Genes & Diseases》2020年第2期253-265,共13页Yongbing Deng Xue Jiang Xiaoyan Deng Hong Chen Jie Xu Zhaosi Zhang Geli Liu Zhu Yong Chengfu Yuan Xiaochuan Sun Changdong Wang 
This study was financially supported by the Education Commission of Chongqing in China(Grant No.KJQN201800124 to Y.B.Deng and Grant No.CY170402 to C.D.Wang);the Natural Science Foundation of Chongqing China(Grant No.cstc2016jcyjA0220 to X.Jiang and Grant No.cstc2014jcyjA10024 to C.D.Wang);Doctoral Program of Higher Education of China(20125503120015 to C.D.Wang).
Traumatic brain injury(TBI)is the major cause of high mortality and disability rates worldwide.Pioglitazone is an activator of peroxisome proliferator-activated receptor-gamma(PPARγ)that can reduce inflammation follo...
关键词:KEYWORDS Traumatic brain injury IL-6 PIOGLITAZONE PPARγ p-NF-kB 
Effectiveness and safety of different doses of pioglitazone in psoriasis:a meta-analysis of randomized controlled trials被引量:3
《Chinese Medical Journal》2020年第4期444-451,共8页Jing-Zhan Zhang Yuan Ding Fang Xiang Shi-Rong Yu De-Zhi Zhang Meng-Meng Guan Xiao-Jing Kang 
Background:Pioglitazone may be beneficial in the treatment of psoriasis.However,based on the effectiveness and safety considerations,it has not been widely used.To fully evaluate the strength of evidence supporting ps...
关键词:META-ANALYSIS PSORIASIS PIOGLITAZONE 
检索报告 对象比较 聚类工具 使用帮助 返回顶部