This work was supported by the grants from the Ministry of Science and Technology of China (No. 2011CB910900 to B.L.) and theNational Natural Science Foundation of China (Nos. 31271377 and 31470802 to B.L.).
The tumor necrosis factor-α (TNF-α) and monocytic cells play a critical role in the development of ath- erosclerosis, which is the major cause of coronary heart disease (CHD). In this work, we investigated the e...
目的探讨细胞因子信号转导抑制因子-1(suppressor of cytokine signaling-1,SOCS1)对氧化型低密度脂蛋白(oxLDL)促进人血管平滑肌细胞(VSMC)增殖作用的影响。方法用脂质体转染法将靶向人SOCS1基因的siRNA(SOCS1-siRNA)和阴性对照siRNA(N...