MONOCYTE

作品数：243被引量：838H指数：14
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Impaired efferocytosis by monocytes and monocyte-derived macrophages in patients with poorly controlled type 2 diabetes
《World Journal of Diabetes》2025年第5期283-296,共14页Qian-Yun Mao Hui Ran Qiu-Yue Hu Sun-Yue He Yao Lu Han Li Yi-Meng Chai Zhao-Yin Chu Xu Qian Wan Ding Yi-Xin Niu Hong-Mei Zhang Xiao-Yong Li Qing Su 
Supported by National Natural Science Foundation of China,No.81970669,No.82170835,and No.82100848;Shanghai Municipal Health Commission,No.202240107,and No.20234Y0040;China Endocrine Metabolism Research Program of Excellence,No.2023-N-03-05。
BACKGROUND Deficient efferocytosis(i.e.,phagocytic clearance of apoptotic cells)by macrophages has been frequently reported in experimental models of type 2 diabetes(T2D).AIM To translate these findings to humans by t...
关键词：Type 2 diabetes EFFEROCYTOSIS MONOCYTE MACROPHAGE 
Comparison of the pathogenicity and neutrophil and monocyte response between SARS-CoV-2 prototype and Omicron BA.1 in a lethal mouse model
《Animal Models and Experimental Medicine》2025年第4期707-717,共11页Na Rong Jing Wu Binbin Zhao Wanjun Peng Hekai Yang Gengxin Zhang Dangting Ruan Xiaohui Wei Jiangning Liu 
supported by Beijing Natural Science Foundation(Grant No.Z210014);National Natural Science Foundation of China(Grant No.32070543);National Key Research and Development Project of China(Grant No.2022YFC2303404);CAMS Innovation Fund for Medical Sciences(CIFMS)(Grant No.2022-12M-CoV19-002)
Background:SARS-CoV-2,first identified in late 2019,has given rise to numerous variants of concern(VOCs),posing a significant threat to human health.The emer-gence of Omicron BA.1.1 towards the end of 2021 led to a pa...
关键词：animal model SARS-CoV-2 Omicron BA.1 MONOCYTE NEUTROPHIL 
Tanyu Tongzhi formula attenuates atherosclerotic plaque vulnerability by inhibiting CD40^(+) monocyte differentiation
《Traditional Medicine Research》2025年第4期61-71,共11页Zheng-Tian Lv Yan-Yun Pan Chen-Xia Wu Yuan-Gang Qiu Shen-Jie Chen Wei Mao Jin Dai 
Natural Science Foundation of Zhejiang Province(grant number LY20H290005);Key Research and Development Program of Zhejiang Province(grant number 2020C03119);National Natural Science Foundation of China(grant numbers 81673706,81973579,82174150);Science and Technology Program of Zhejiang Traditional Chinese Medicine(grant number 2018ZY005);TCM science and Technology Foundation Project of Zhejiang Province(grant number 2023ZL411).
Background:Atherosclerosis(AS)is a chronic progressive inflammatory disease,and plaque stability plays a critical role in preventing acute events.Tanyu Tongzhi formula(TTF),a traditional Chinese medicine,has potential...
关键词：ATHEROSCLEROSIS Tanyu Tongzhi formula CD40^(+)monocyte differentiation inflammation 
Pro-resolving lipid mediator reduces amyloid-β42–induced gene expression in human monocyte–derived microglia
《Neural Regeneration Research》2025年第3期873-886,共14页Ying Wang Xiang Zhang Henrik Biverstål Nicolas GBazan Shuai Tan Nailin Li Makiko Ohshima Marianne Schultzberg Xiaofei Li 
supported by the China Scholarship Council(to YW);the Swedish Research Council,No.2018-02601(to MS);the Alzheimer Foundation,No.AF-980695(to MS);the Stockholm County Council,No.RS2020-0731(to MS);the Foundation of Old Servants(to MS);the Gun and Bertil Stohne Foundation(to MS);the?hlén Foundation,No.233055(to MS);The Swedish Fund for Research without Animal Experiments(to MS);the Swedish Dementia Foundation(to MS);the Brain foundation,No.FO2022-0131(to MS)。
Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the treatment of Al...
关键词：Alzheimer's disease amyloid-β maresin MICROGLIA MONOCYTE NEUROINFLAMMATION resolution RNA-sequencing specialized pro-resolving lipid mediator 
Protective effects of autologous bone marrow-derived mesenchymal stem cell transplantation on acute radioactive enteritis in Beagle dogs
《World Journal of Gastroenterology》2025年第7期98-109,共12页Guang-Chen Sun Wen-Da Xu Hui Yao Jiang Chen Ruo-Nan Chai 
Supported by People's Livelihood Science and Technology Plan Joint Project of Liaoning Province,No.2021JH2/10300083。
BACKGROUND Radiation enteritis is a common complication of radiation therapy in which the surrounding normal intestinal tissue is damaged by ionising radiation,and there is no standard pharmacological prophylaxis or t...
关键词：Mesenchymal stem cells TRANSPLANTATION Acute radioactive enteritis Antibody array Interleukin 10 Monocyte chemotactic protein-1 
Features of the monocyte inflammatory response in patients with premature coronary artery disease
《Biophysics Reports》2025年第1期12-17,共6页Tatiana Blokhina Tatiana Kirichenko Yuliya Markina Ulyana Khovantseva Ivan Melnikov Olga Guseva Sergey Bazanovich Sergey Kozlov Alexander Orekhov 
supported by Russian Science Foundation(22-15-00134)。
The purpose of this study was to examine the secretion of inflammatory cytokines by cultured monocytes/macrophages in patients with premature coronary artery disease(CAD).The study included 38patients with premature C...
关键词：Coronary artery disease MONOCYTES Inflammatory cytokines Immune tolerance 
Immune indicators and depression in adolescents:Associations with monocytes,lymphocytes,and direct bilirubin
《World Journal of Psychiatry》2025年第2期23-32,共10页Jian Dai Xiao-Tong Lin Lu-Lu Shen Xi-Wen Zhang Zi-Wen Ding Jing Wang Xi-Wang Fan Wei-Dong Ning 
Supported by the Medical Discipline Construction Project of Pudong Health Committee of Shanghai,No.PWZzb2022-09;Nanning City Science Research and Technology Development Program,No.ZC20233017;and Guangxi Medical and Health Appropriate Technology Development and Promotion Project,No.S2021061.
BACKGROUND Depression is a significant psychiatric disorder with particularly high prevalence among adolescents.This mental health condition can have severe consequences,including academic failure,social withdrawal,an...
关键词：DEPRESSION Adolescents Immune markers MONOCYTE LYMPHOCYTE Direct bilirubin 
Integrated analysisof monocyte infiltration and differential gene expressionin hypertrophic obstructive cardiomyopathy
《South China Journal of Cardiology》2024年第4期260-274,共15页QIN Xian-yu TAN Jian ZHENG Hao-sheng ZHENG Yu-zhen LIAO Hong-ying ZHUANG Jian 
National Natural Science Foundation of China(No.82102955);Guangzhou Basic Research Project(No.02201011326)。
Background Hypertrophic obstructive cardiomyopathy(HOCM)is one of the main reasons for sudden cardiac death(SCD)in young people.Researches has revealed that immune-related genes are closely relevant to HOCMprogression...
关键词：Hypertrophic cardiomyopathy Hypertrophic obstructive cardiomyopathy Immune infiltration Immune cell subtype 
Monocyte to high-density lipoprotein cholesterol ratio as a predictor of the activity of thyroid-associated ophthalmopathy
《International Journal of Ophthalmology(English edition)》2024年第12期2276-2281,共6页Xing-Hong Sun Xiao-Wen Zhang Chen Han Xin Dou Xue-Ying He Meng-Ru Su Feng Jiang Song-Tao Yuan 
Supported by the Special Fund for Clinical Research of Nanjing Drum Tower Hospital(No.2023-LCYJPY-37).
AIM:To evaluate the relationship between monocyte to high-density lipoprotein cholesterol ratio(MHR)and the disease activity of thyroid-associated ophthalmopathy(TAO).METHODS:A total of 87 patients were classified int...
关键词：thyroid-associated ophthalmopathy monocyte to high-density lipoprotein cholesterol ratio disease activity 
Clinical Value of Platelet-Related Parameters and Monocyte Counts in Patients with Oculomotor Myasthenia Gravis
《Case Reports in Clinical Medicine》2024年第12期572-580,共9页Yaping Sun Xianglin Cheng Ke Peng 
Background: Our study aimed to investigate the clinical value of platelet parameters and the number of Monocytes (MONO) in the peripheral blood of patients with Ocular Myasthenia Gravis (OMG). Methods: Fifty patients ...
关键词：Ocular Myasthenia Gravis Mononuclear Cell Platelet Distribution Width 
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