supported by Shenzhen Science and Technology Program (JCYJ20200109105803806, SGDX20201103095802006, RCYX20200714114535052,JCYJ20190808150001775,and CYJ20190808143007479);the National Natural Science Foundation of China (U21A20312 and 21975162);Guangdong Basic and Applied Basic Research Foundation (2022B1515120084)。