supported in part by funds from the Department of Basic Sciences Loma Linda University Health(LLUH)School of Medicine;the Grants for Research and School Partnerships award(LLUH intramural grant);the Grants to Promote Collaborative and Translational Research Award(LLUH intramural grant);NIH/National Institute of General Medical Sciences grant(award number 2R25GM060507);the National Institutes of Health(NIH)(Grant No.S10OD019960)。
Metastatic breast cancer is incurable and often due to breast cancer stem cell(CSC)-mediated self-renewal.We previously determined that the aryl hydrocarbon receptor(AhR)agonist aminoflavone(AF)inhibits the expression...