RANIBIZUMAB

作品数:167被引量:618H指数:14
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相关领域:医药卫生更多>>
相关作者:王德功陈松林莉宫丽段红涛更多>>
相关机构:天津市眼科医院武汉大学北京医院天津医科大学更多>>
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相关基金:国家自然科学基金天津市科技计划上海市卫生局青年科研基金福建省科技重点项目更多>>
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Effect of simultaneous intravitreal ranibizumab and extended-release dexamethasone injection on patients with naïve versus refractory retinal vein occlusion macular edema:a prospective,multicenter,and interventional open-label study
《International Journal of Ophthalmology(English edition)》2025年第5期860-867,共8页Yao-Yao Sun Jie Meng Shan-Shan Li Qin Xiao Tian-Zi Zhang Heng Miao Ming-Wei Zhao Hui-Jun Qi 
Supported by the National Nature Science Foundation of China(No.82301211);Beijing Natural Science Foundation(No.J230028).
AIM:To evaluate the efficacy and safety of concurrent intravitreal ranibizumab(IVR)and extended-release dexamethasone injections(Dex-I)in naïve and refractory patients with retinal vein occlusion macular edema(RVO-ME)...
关键词:retinal vein occlusion macular edema prospective clinical trial anti-vascular endothelial growth factor dexamethasone implant 
Effect of ranibizumab on diabetic retinopathy via the vascular endothelial growth factor/STAT3/glial fibrillary acidic protein pathway
《World Journal of Diabetes》2025年第5期234-253,共20页Ye-Ting Lin Jian Tan Yu-Lin Tao Wei-Wen Hu Yi-Cang Wang Jing Huang Qiong Zhou Ang Xiao 
Supported by the Natural Science Foundation of Jiangxi Province,No.20242BAB25489;National Natural Science Foundation of China,No.82260211 and No.81460092;Key Research and Development Project in Jiangxi Province,No.20203BBG73058;Chinese Medicine Science and Technology Project in Jiangxi Province,No.2020A0166。
BACKGROUND Diabetic retinopathy(DR)is the leading cause of vision loss in patients with diabetes.The vascular endothelial growth factor(VEGF)pathway plays a critical role in the pathogenesis of DR,and ranibizumab,an a...
关键词:Diabetic retinopathy RANIBIZUMAB Early stage Vascular endothelial growth factor Signal transducer and activator of transcription 3 Glial fibrillary acidic protein 
Comparison of Aflibercept and Ranibizumab on Functional and Morphological Outcome in Exudative Age-Related Macular Degeneration
《Journal of Biosciences and Medicines》2025年第2期330-347,共18页Xue Wang Chaofeng Yu Jingjing Ding 
Background: Exudative, or “wet” age-related macular degeneration (wAMD), characterized by choroidal neovascularization and consequent accumulation of subretinal fluid, is the leading cause of visual loss in elderly ...
关键词:RANIBIZUMAB AFLIBERCEPT Age-Related Macular Degeneration 
Comparison of the effect of ranibizumab in retinal vein occlusion and macular edema with different optical coherence tomographic patterns
《International Journal of Ophthalmology(English edition)》2025年第2期275-282,共8页Yue Xu Yue-Cong Yin Ze-Yu Song Xiao-Yu Zhou Jia-Ju Zhang Juan Liang 
Supported by the Suzhou Medical Innovation Application Research Project(SZM2023027).
AIM:To explore the morphological and functional parameters to evaluate the effectiveness of intravitreal injections of ranibizumab(IVR)in treating macular edema(ME)secondary to retinal vein occlusion(RVO).METHODS:This...
关键词:retinal vein occlusion optical coherence tomography serous retinal detachment cystoid macular edema diffuse retinal thickening 
Comparison of efficacy and safety of intravitreal ranibizumab and conbercept before vitrectomy in Chinese proliferative diabetic retinopathy patients:a prospective randomized controlled trial
《Eye and Vision》2024年第6期33-40,共8页Siying Li Lili Guo Pingping Zhou Jiyang Tang Zongyi Wang Linqi Zhang Mingwei Zhao Jinfeng Qu 
funded by Capital Clinical Diagnosis and Treatment Technology Research and Demonstration Application Project of China(Grant No.Z191100006619029);National Key R&D Program of China(Grant No.2020YFC2008200).
Background:To compare the efficacy and safety of preoperative intravitreal injections of ranibizumab and conbercept in Chinese proliferative diabetic retinopathy(PDR)patients.Methods:This prospective randomized contro...
关键词:Proliferative diabetic retinopathy ANTI-VEGF RANIBIZUMAB Conbercept Preoperative intravitreal injections Diabetic vitrectomy Efficacy Safety 
Intravitreal long-term sustained ranibizumab delivery using injectable microgel-embedded hydrogel
《Asian Journal of Pharmaceutical Sciences》2024年第5期126-138,共13页Simin Lee Jun Young Park Hye Kyoung Hong Joo Young Son Byungwook Kim Jae Yong Chung Se Joon Woo Ki Dong Park 
This study was supported by a grant(2019R1A6A1A11051471)from Priority Research Centers Program which was funded by the National Research Foundation of Korea(NRF);the Bio&Medical Technology Development Program(2018M3A9B5021319)which was funded by the Ministry of Science and ICT,South Korea(MSIT);a grant from Seoul National University Bundang Hospital(14-2023-0001);a grant from Korea Medical Device Development Fund by the Korea government(RS-2020-KD000033);a grant from the Alchemist Project of Korea Evaluation Institute of Industrial Technology(KEIT 20018560,NTIS 1415184668)which was funded by the Ministry of Trade,Industry&Energy.
Retinal vascular disease is the leading cause of visual impairment.Although intravitreal drug injections are the most suitable approach for addressing retinal disorders,existing clinical treatments necessitate repeate...
关键词:Age-related macular degeneration RANIBIZUMAB Microgel-embedded hydrogel Long-term drug delivery Pharmacokinetics Biodegradation 
Effectiveness of intravitreal ranibizumab for diabetic macular edema in vitrectomized versus non-vitrectomized eyes:a Meta-analysis
《International Journal of Ophthalmology(English edition)》2024年第4期729-735,共7页Yi-Heng Wang Qian Xu Jie Luan 
AIM:To evaluate the effectiveness and safety of intravitreal ranibizumab(IVR)for diabetic macular edema(DME)in vitrectomized versus non-vitrectomized eyes.METHODS:The PubMed,EMBASE,Web of Science,Cochrane,EBSCO were c...
关键词:diabetic macular edema RANIBIZUMAB vitrectomized eye 
Different approaches for treating myopic choroidal neovascularization:a network Meta-analysis
《International Journal of Ophthalmology(English edition)》2023年第12期2105-2116,共12页Ya-Jun Wu Yu-Liang Feng Jia-Song Yang Hua Fan Wen-Sheng Li 
Supported by 2023 Research Fund of Aier Ophthalmology Research Institute(No.AEI202310LC01).
AIM:To evaluate the efficacy of intravitreal injection of anti-vascular endothelial growth factor(anti-VEGF),photodynamic therapy(PDT),and laser treatment(LT)for anatomical and functional improvement in myopic choroid...
关键词:myopic choroidal neovascularization AFLIBERCEPT BEVACIZUMAB conbercept laser treatment RANIBIZUMAB photodynamic therapy 
Comparison of efficacy of conbercept,aflibercept,and ranibizumab ophthalmic injection in the treatment of macular edema caused by retinal vein occlusion:a Meta-analysis被引量:2
《International Journal of Ophthalmology(English edition)》2023年第7期1145-1154,共10页Qiu Xing Ya-Nan Dai Xiao-Bo Huang Li Peng 
Supported by the Natural Science Foundation of Hainan Province(No.821QN1005);Hainan Provincial Health Commission Project(No.21A200067);Hainan Provincial Classification of Project(No.ZDYF2020110)。
AIM:To evaluate and compare the anatomical and functional outcomes and negative effects of the three anti-vascular endothelial growth factor(VEGF)drugs in the treatment of macular edema(ME)due to retinal vein occlusio...
关键词:anti-vascular endothelial growth factor conbercept AFLIBERCEPT RANIBIZUMAB macular edema retinal vein occlusion 
Analysis of the Efficacy of Triamcinolone Acetonide Combined with Ranibizumab in the Treatment of Fundus Diseases
《Journal of Clinical and Nursing Research》2023年第6期30-35,共6页Wanqiu Jiao Jingwei Zhang Ning Ma Zhigang Ma 
Objective:To analyze the effect of triamcinolone acetonide combined with ranibizumab in patients with fundus diseases.Methods:100 patients with fundus diseases admitted from January 2018 to January 2023 were selected....
关键词:Intravitreal injection of ranibizumab Monoclonal antibody treatment Fundus diseases Adverse reactions Quality of life 
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