SCFA

作品数:62被引量:268H指数:9
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Understanding the mechanism underlying the anti-inflammatory effect of dietary flavonoids on IBD:a focus on gut microbiota and its metabolites involved in SCFA,bile acid,tryptophan and lipopolysaccharides
《Food Science and Human Wellness》2025年第2期385-403,共19页Huihui Xiong Hui Chen Lingli Chen Kehui Ouyang Suyun Lin Wenjun Wang 
supported by grants from the National Natural Science Foundation of China(31560459);Jiangxi Provincial Natural Science Foundation(20224ACB205014);The Double Thousands Talents Plan of Jiangxi(jxsq2018102075,jxsq2018102076)。
Inflammatory bowel disease(IBD)is a chronic gastrointestinal disease with a high incidence.Treatment for IBD includes medications and diet,and common anti-inflammatory medications have limitations like drug resistance...
关键词:Dietary flavonoids Inflammatory bowel disease Gut microbiota METABOLITES Mechanisms 
小儿开胃增食合剂调控SCFAs-FFAR2-IL-18通路关键因子增强厌食症幼龄大鼠机体免疫
《中药药理与临床》2025年第1期70-76,共7页景姬 李玉霞 何岳珍 张雪 马思淼 
国家自然科学基金(编号:81603660、82160921);甘肃省自然科学基金项目(编号:22JR5RA572)。
目的:观察小儿开胃增食合剂对模型大鼠厌食症发生发展的影响,探讨其基于SCFAs-FFAR2-IL-18通路关键因子治疗小儿厌食症的相关机制。方法:以病因模拟法构建大鼠厌食症模型,记录大鼠摄食量和体质量变化,以双歧杆菌四联活菌片0.405 g/kg组...
关键词:小儿开胃增食合剂 小儿厌食症 短链脂肪酸 游离脂肪酸受体2 白介素-18 
红芪多糖经SCFAs-GPCRs改善脾气虚型DGP大鼠小肠动力的机制研究
《中华中医药杂志》2024年第7期3436-3441,共6页魏昭晖 李荣科 张磊 刘苗 万生芳 
国家自然科学基金项目(No.82060914);中医学一流学科“岐黄英才”导师专项基金;甘肃省优秀博士生项目(No.23JRRA1225);甘肃中医药大学研究生创新项目(No.2022-07)。
目的:观察红芪多糖(HPS)对脾气虚型糖尿病胃轻瘫(DGP)大鼠短链脂肪酸(SCFAs)-G蛋白偶联受体(GPCRs)的影响,探讨HPS改善脾气虚型DGP大鼠小肠动力的可能机制。方法:72只SPF级Wistar雄性大鼠随机分为空白组(10只)和造模组(62只),造模组采...
关键词:糖尿病胃轻瘫 红芪多糖 G蛋白偶联受体 短链脂肪酸 肠动力 机制 动物模型 
Multi-Compartment SCFA Quantification in Human
《American Journal of Analytical Chemistry》2024年第6期177-200,共24页Jérémy Monteiro Antoine Lefèvre Diane Dufour-Rainfray Adeline Oury Gabrielle Chicheri Laurent Galineau Hélène Blasco Lydie Nadal-Desbarats Patrick Emond 
Short-chain fatty acids (SCFA) play an important role in human biochemistry. They originate primarily from the digestive system through carbohydrates microbial fermentation. Most SCFA produced in the colon are absorbe...
关键词:LC-MS 3-Nitrophenylhydrazine Short-Chain Fatty Acids Human Biological Samples Quantification 
Effects of forsythin extract in Forsythia leaves on intestinal microbiota and short-chain fatty acids in rats fed a high-fat diet
《Food Science and Human Wellness》2024年第2期659-667,共9页Lanlan Gui Shaokang Wang Jing Wang Wang Liao Zitong Chen Da Pan Hui Xia Guiju Sun Su Tian 
funded by grants from the National Key R&D Program of China(2016YFD0500604)。
Forsythia suspensa,belonging to the deciduous shrubs of the Luteaceae family,a traditional Chinese medicine,has effects of alleviating swelling,clearing heat,detoxification and promoting blood circulation.The leaves o...
关键词:FORSYTHIN High-fat diet Intestinal microbiota Short-chain fatty acid(SCFA) 
基于肠道菌群及其代谢产物SCFA探讨左归降糖通脉方对2型糖尿病大鼠糖脂代谢的影响被引量:4
《湖南中医药大学学报》2024年第3期365-373,共9页彭岚玉 李定祥 姚敬心 罗政 邓奕辉 
湖南省教育厅科学研究项目(21A0228);湖南省中医药科研计划项目(E2022010);湖南中医药大学中西医结合一流学科开放基金项目(2020ZXYJH31)。
目的基于肠道菌群及代谢产物短链脂肪酸(short-chain fatty acid,SCFA)探讨左归降糖通脉方(Zuogui Jiangtang Tongmai formula,ZJTF)干预2型糖尿病(type 2 diabetes mellitus,T2DM)的可能机制。方法取12只SD大鼠为空白(Control)组,喂食...
关键词:左归降糖通脉方 2型糖尿病 肠道菌群 短链脂肪酸 糖脂代谢 
黄连温胆汤调控SCFAs-GPR41/43-GLP1信号通路干预2型糖尿病模型大鼠的作用机制被引量:8
《中药药理与临床》2023年第12期2-7,共6页熊秋迎 邹海虹 王雨豪 胡珊 肖星华 朱金华 
江西省卫生健康委员会科技计划项目(编号:202130197)。
目的:基于SCFAs-GPR41/43-GLP1信号通路研究黄连温胆汤对2型糖尿病模型大鼠的干预机制。方法:选择SPF级SD雄性大鼠80只,先随机分10只为正常对照组,其余大鼠以高糖高脂乳剂10 mL/kg灌胃,监测血糖1次/w, 8 w后,腹腔注射STZ 35 mg/kg诱导2...
关键词:黄连温胆汤 2型糖尿病 短链脂肪酸 G蛋白偶联受体41/43 胰高血糖素样肽-1 肽YY 
New insights in the metabolic function related to gut microbiota in the process of liver regeneration被引量:2
《Hepatobiliary Surgery and Nutrition》2023年第6期933-935,共3页Nan Jiang Zhen Wang Kefei Yuan 
Liver disease is a prominent cause of premature mortality globally(1).Many patients with liver diseases require therapeutic liver surgery,usually through hepatectomy(2).Due to the clinical demand for such practice,the...
关键词:Liver regeneration gut microbiota short-chain fatty acid(SCFA) 
Potential roles of the rectum keystone microbiota in modulating the microbial community and growth performance in goat model
《Journal of Animal Science and Biotechnology》2023年第5期2048-2062,共15页Dangdang Wang Guangfu Tang Lichao Zhao Mengya Wang Luyu Chen Congcong Zhao Ziqi Liang Jie Chen Yangchun Cao Junhu Yao 
supported by the National Natural Science Foundation of China(32072761,32272829);the National Key Research and Development Program of China(2017YFD500500).
Background Ruminal microbiota in early life plays critical roles in the life-time health and productivity of ruminant animals.However,understanding of the relationship between gut microbiota and ruminant phenotypes is...
关键词:Early life GOAT Growth performance Rectum microbiota SCFA 
Dietary folic acid addition reduces abdominal fat deposition mediated by alterations in gut microbiota and SCFA production in broilers
《Animal Nutrition》2023年第1期54-62,共9页Yanli Liu Jiantao Yang Xiaoying Liu Rui Liu Yibin Wang Xinhuo Huang Yingge Li Ruifang Liu Xiaojun Yang 
This work was funded by the National Science Foundation of China(No 32102567 and 31972529);the Program for Shaanxi Science&Technology(2022KJXX-13).
Intensive selective breeding for high growth rate and body weight cause excess abdominal fat in broilers.Gut microbiota and folic acid were reported to regulate lipid metabolism.A total of 210 one-day-old broilers wer...
关键词:Folic acid Caecal microbiota Abdominal adipocytes Short chain fatty acid BROILERS 
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