SHP-1

作品数：103被引量：161H指数：5
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相关机构：河北医科大学第二医院河北医科大学第二军医大学哈励逊国际和平医院更多>>
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  • 期刊=Chemical Research in Chinese Universitiesx
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Effect of Candesartan Cilexetil as a Sensitive and Effective Inhibitor of SHP-1 on Insulin Signaling Pathway
《Chemical Research in Chinese Universities》2013年第4期730-734,共5页ZHANG Lei ZHANG Shi-tao ZHANG Xiao-ping SUN Jing WANG Yong-sen LIU Yue-long XUE Miao-miao WANG Zhi XING Shu MA Jun-feng LI Wan-nan FU Xue-qi 
Supported by the National Natural Science Foundation of China（Nos.81102859, 81000202, 31000358） and the Research Fund for the Doctoral Program of Higher Education of China（No.20090061110019）.
The protein tyrosine phosphatases（PTPs） comprise a family of enzymes that specifically dephosphorylate tyrosyl residues. Among them, SHP-I has been regarded as one of the best validated intracellular tyrosine phosph...
关键词：SHP-1 Candesartan cilexetil INHIBITOR Insulin sensitivity 
Structural Analysis of an Oligosaccharide and Glycopeptide Mixture from Panax Ginseng Root with Inhibition SHP-1 Function
《Chemical Research in Chinese Universities》2011年第1期104-107,共4页WANG Ying GAO Qi-pin LI Gui-rong CHEN Ying-hong LUO Hao-ming GAO Yang JIANG Rui-zhi 
Supported by the National Science & Technology Pillar Program of China(No2007BA138B00)
A mixture of oligosaccharide and glycopeptide was isolated from the aqueous extract of Panax ginseng roots. The mixture inhibits protein tyrosinc phosphatase（SHP-1） function, implying it enhances immune activity. Th...
关键词：Panax ginseng OLIGOSACCHARIDE GLYCOPEPTIDE Protein tyrosine phosphatase（SHP-1） Methylation analysis 
Purification and Characterization of the Catalytic Domain of Protein Tyrosine Phosphatase SHP-1 and the Preparation of Anti-ΔSHP-1 Antibodies被引量：3
《Chemical Research in Chinese Universities》2008年第5期592-596,共5页LI Wan-nan ZHUANG Yan LI He SUN Ying FU Yao WU Xiao-xia ZHAO Zhi-zhuang FU Xue-qi 
the Fund of Science & Technology Bureau of Jilin Province, China(Nos.20060563, 200705394 and 20080434).
This study is focused on the expression of an SH2 domain-truncated form of protein tyrosine phosphatase SHP-1（designated ΔSHP-1） and the preparation of its polyclonal antibodies. A cDNA fragment encoding ΔSHP-1 wa...
关键词：SHP-1 Protein tyrosine phosphatase Polyclonal antibodies 
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