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Cloning of a gene-edited macaque monkey by somatic cell nuclear transfer被引量:17
《National Science Review》2019年第1期101-108,共8页Zhen Liu Yijun Cai Zhaodi Liao Yuting Xu Yan Wang Zhanyang Wang Xiaoyu Jiang Yuzhuo Li Yong Lu Yanhong Nie Xiaotong Zhang Chunyang Li Xinyan Bian Mu-ming Poo Hung-Chun Chang Qiang Sun 
supported by grants from the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB32060100 to Q.S.,XDB32060200 to H-C.C.and 32070100to M-m.P.);the Shanghai Municipal Science and Technology Major Project(2018SHZDZX05 to Q.S.,Z.L.,H-C.C.and M-m.P.);the Shanghai Municipal Government Bureau of Science and Technology(18JC1410100 to Q.S.,H-C.C.and M-m.P.);the Ministry of Science and Technology(973 Program,2011CBA00400);the Institute of Neuroscience Director’s Fund(to M-m.P.);the National Postdoctoral Program for Innovative Talents(to Z.L.);the National Key Research and Development Program of China(2018YFC1003000 to Q.S.and Z.L.);the National Natural Science Foundation of China Grant(31825018to Q.S.)
Cloning of macaque monkeys by somatic cell nucleus transfer(SCNT) allows the generation of monkeys with uniform genetic backgrounds that are useful for the development of non-human primate models of human diseases. He...
关键词:MACAQUE monkey CLONING SOMATIC cell nuclear transfer non-human PRIMATE models CRISPR/Cas9 GENE editing CIRCADIAN rhythm disorders 
Polycomb-group histone methyltransferase CLF is required for proper somatic recombination in Arabidopsis
《Journal of Integrative Plant Biology》2014年第6期550-558,共9页Na Chen Wang-Bin Zhou Ying-Xiang Wang Ai-Wu Dong Yu Yu 
supported by the National Basic Research Program of China (973 Program, grants nos. 2012CB910500 and 2011CB944600);the National Natural Science Foundation of China (31371304)
Homologous recombination (HR) is a key process during meiosis in reproductive cells and the DNA damage repair process in somatic cells. Although chromatin structure is thought to be crucial for HR, only a smal numbe...
关键词:ARABIDOPSIS CLF DNA repair homologous recombination MEIOSIS 
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