This work was supported by the National Natural Science Found ation of China(32273000);the Qingdao Demonstration Project for People-benefit from Science and Techniques,China(23-2-8-xdny-14nsh and 24-2-8-xdny-4-nsh);the National Program of Undergraduate Innovation and Entrepreneurship,China(202310435039);the Open Project Fund of State Key Laboratory of Microbial Technology,China(M2023-03)。
Senecavirus A(SVA)has a positive-sense,single-stranded RNA genome.Its 5´untranslated region harbors an internal ribosome entry site(IRES),comprising 10 larger or smaller stem-loop structures(including a pseudoknot)th...