This study was supported by grants 2015CB943400 and 2014CB943300 from the Ministry of Science and Technology of China;grant XDB19000000 from the“Strategic priority research program of the Chinese Academy of Sciences”;grants 91542102 and 31570887 from the National Natural Science Foundation of China;China's Youth 1000 Talent Program to Q.J.
OX40L is one of the co-stimulatory molecules that can be expressed by splenic lymphoid tissue inducer(Lti)cells,a subset of group 3 innate lymphoid cells(ILC3s).OX40L expression in subsets of intestinal ILC3s and the ...
This work was supported by the National Natural Science Foundation of China (81472468, 81672614, 81622036, 81490750, 81230060, 81442009, 81472467, 81272894, 81372816 and 81372819), the Science Foundation of Guangdong Province (2016A030306023, 2014A030313094, $2012030006287, 2014A030313175), the National Basic Research Program of China (973 Projects; SQ2015CB050449), Guangzhou Science Technology and Innovation Commission (201508020008, 201508020249), Guangdong Science and Technology Department (2015B050501004), Translational Medicine Public Plat- form of Guangdong Province (4202037), Guangdong Depart- ment of Science & Technology Translational Medicine Center (2011A080300002), Sun Yat-Sen University (16ykpy07), Breast Cancer Alliance Exceptional Project Grant and US National Cancer Institute RO1 CA211694.
The origin of tumor-infiltrating Tregs, critical mediators of tumor immunosuppression, is unclear. Here, we show that tumor-infiltrating naive CD4+ T cells and Tregs in human breast cancer have overlapping TCR repert...
Supported by National Natural Science Foundation of China,No.81130035,No.81372054,No.81071545,and No.81121004;the National Basic Research Program of China,No.2012CB518102
AIM: To assess systematically the association between regulatory T cells (Tregs) and hepatocellular carcinoma (HCC).
supported by National 973 Project in Viral Hepatitis,China (MOST,No. 2007CB512900)
CD4 + CD25 + CD127 dim/regulatory T cells(Tregs) have been implicated in suppressing T cell immune responses to hepatitis B virus(HBV),but the inhibition mechanism has not being clear yet.This study investigated the e...