TREGS

作品数:164被引量:692H指数:12
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相关领域:医药卫生更多>>
相关作者:刘静杨懿铭杨洁洪永敦余锋更多>>
相关机构:中山大学天津医科大学安徽医科大学新疆医科大学更多>>
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ILC3-derived OX40L is essential for homeostasis of intestinal Tregs in immunodeficient mice被引量:4
《Cellular & Molecular Immunology》2020年第2期163-177,共15页Tian Deng Caixia Suo Jiali Chang Rui Yang Jingyu Li Ting Cai Ju Qiu 
This study was supported by grants 2015CB943400 and 2014CB943300 from the Ministry of Science and Technology of China;grant XDB19000000 from the“Strategic priority research program of the Chinese Academy of Sciences”;grants 91542102 and 31570887 from the National Natural Science Foundation of China;China's Youth 1000 Talent Program to Q.J.
OX40L is one of the co-stimulatory molecules that can be expressed by splenic lymphoid tissue inducer(Lti)cells,a subset of group 3 innate lymphoid cells(ILC3s).OX40L expression in subsets of intestinal ILC3s and the ...
关键词:Group 3 innate lymphoid cells OX40L Regulatory T cells Intestinal immunity 
Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer被引量:24
《Cell Research》2017年第4期461-482,共22页Shicheng Su Jianyou Liao Jiang Liu Di Huang Chonghua He Fei Chen LinBing Yang Wei Wu Jianing Chen Ling Lin Yunjie Zeng Nengtai Ouyang Xiuying Cui Herui Yao Fengxi Su Jian-dong Huang Judy Lieberman Qiang Liu Erwei Song 
This work was supported by the National Natural Science Foundation of China (81472468, 81672614, 81622036, 81490750, 81230060, 81442009, 81472467, 81272894, 81372816 and 81372819), the Science Foundation of Guangdong Province (2016A030306023, 2014A030313094, $2012030006287, 2014A030313175), the National Basic Research Program of China (973 Projects; SQ2015CB050449), Guangzhou Science Technology and Innovation Commission (201508020008, 201508020249), Guangdong Science and Technology Department (2015B050501004), Translational Medicine Public Plat- form of Guangdong Province (4202037), Guangdong Depart- ment of Science & Technology Translational Medicine Center (2011A080300002), Sun Yat-Sen University (16ykpy07), Breast Cancer Alliance Exceptional Project Grant and US National Cancer Institute RO1 CA211694.
The origin of tumor-infiltrating Tregs, critical mediators of tumor immunosuppression, is unclear. Here, we show that tumor-infiltrating naive CD4+ T cells and Tregs in human breast cancer have overlapping TCR repert...
关键词:naive CD4+ T cells breast cancer TREGS CCL 18 tumor immunosuppression 
Roles of Tregs in development of hepatocellular carcinoma:A meta-analysis被引量:5
《World Journal of Gastroenterology》2014年第24期7971-7978,共8页Hong-Qiang Zhao Wei-Min Li Zhong-Qiou Lu Yong-Ming Yao 
Supported by National Natural Science Foundation of China,No.81130035,No.81372054,No.81071545,and No.81121004;the National Basic Research Program of China,No.2012CB518102
AIM: To assess systematically the association between regulatory T cells (Tregs) and hepatocellular carcinoma (HCC).
关键词:Hepatocellular carcinoma Regulatory T cells META-ANALYSIS Tumor escape Cellular immunity 
Inhibitory Function of Tregs via Soluble FGL2 in Chronic Hepatitis B
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2012年第4期540-545,共6页徐莉 杨道峰 刘艳玲 吴迪 王晓晶) 宁琴 
supported by National 973 Project in Viral Hepatitis,China (MOST,No. 2007CB512900)
CD4 + CD25 + CD127 dim/regulatory T cells(Tregs) have been implicated in suppressing T cell immune responses to hepatitis B virus(HBV),but the inhibition mechanism has not being clear yet.This study investigated the e...
关键词:soluble FGL2 protein regulatory T cells CD8 + T cells chronic hepatitis B 
不同方法检测肝癌患者外周血中CD^(4+)CD25^(hi-int)Tregs水平的关系及意义被引量:1
《世界华人消化杂志》2010年第13期1384-1389,共6页王芳 吕洪敏 韩涛 王鹏 王凤梅 朱争艳 向慧玲 
国家重点基础研究发展规划(973计划)基金资助项目;No.2007CB512801;科技部科技重大专项基金资助项目;No.2008ZX10002-005;天津市科委重点攻关专项基金资助项目;No.05YFSZSF02500;天津市科委应用基础研究计划面上基金资助项目;No.06YFJMJC13100~~
目的:探讨以标记CD127low和Foxp3+两种方法检测肝癌(hepatocellular carcinoma,HCC)患者外周血中CD4+CD25hi-intTregs水平的相关性,建立两者转换的回归方程.方法:流式细胞术同时用CD127low和Foxp3+两种标志物检测31例HCC患者外周血中CD4...
关键词:肝癌 CD4+CD25hi-intCD127lowTregs CD4+CD25hi-intFoxp3+Tregs 
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