云南高校图书馆联盟文献共享服务平台- VARIANTS

VARIANTS: 作品数：613被引量：1047H指数：14; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：张启发谈移芳吴松顾先明谢金燕更多>>; 相关机构：华南农业大学电子科技大学哈尔滨医科大学复旦大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>

Simulating potential outbreaks of Delta and Omicron variants based on contact-tracing data:A modelling study in Fujian Province,China被引量：2: 《Infectious Disease Modelling》2023年第1期270-281,共12页Yichao Guo Wenjing Ye Zeyu Zhao Xiaohao Guo Wentao Song Yanhua Su Benhua Zhao Jianming Ou Yanqin Deng Tianmu Chen; supported by the Bill&Melinda Gates Foundation(INV-005834),Natural Science Foundation of Fujian Province(NO.2021J01353,NO.2020J01094);National Science and Technology Major Project of the Ministry of Science and Technology of China(NO.2018ZX10734402-007);Research on accurate prediction and timely response system for out-breaks of new infectious diseases(SRPG2200702);Fundamental Research Funds for the Central Universities(No.20720230001).; Although studies have compared the relative severity of Omicron and Delta variants by assessing the relative risks,there are still gaps in the knowledge of the potential COVID-19 burden these variations may cause.And ...; 关键词：Contact tracing Vaccine effectiveness Variant of concern Mathematical model COVID-19

Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants,including Omicron sublineages被引量：1: 《Cell Research》2022年第7期691-694,共4页Lei Wang Wangjun Fu Linlin Bao Zijing Jia Yuxia Zhang Yunjiao Zhou Wei Wu Jianbo wu Qianqian Zhang Yidan Gao Kang Wang Qiao Wang Chuan Qin Xiangxi Wang; supported by Ministry of Science and Technology of China(CPNL2022A-03-03,CPNL-1233,EKPG21-09),CAS(YSBR-010),the Strategic Priority Research Program(XDB29010000,XDB37030000);the National Key R&D Program(2020YFA0707500,2018YFA0900801,2021YFA1301400);the National Natural Science Foundation of China(31872730,32070947);Beijing Municipal Science and Technology Project(Z201100005420017);supported by Ten Thousand Talent Program and the NSFS Innovative Research Group(81921005).; Dear Editor,The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),belonging to the lineage B of the genus Betacoronavirus in the Coronaviridae family,is the causative agent of the C0VID19 pandemic,1 which ha...; 关键词：HAS BASES NEUTRAL

Structure-based analyses of neutralization antibodies interacting with naturally occurring SARS-CoV-2 RBD variants被引量：2: 《Cell Research》2021年第10期1126-1129,共4页Hua Xu Bo Wang Tian-Ning Zhao Zi-Teng Liang Tian-Bo Peng Xiao-Hui Song Jia-Jing Wu You-Chun Wang Xiao-Dong Su; We thank the National Center for Protein Sciences at Peking University in Beijing,China,for assistance with SPR assay.We thank the staff of the Shanghai Synchrotron Radiation Facility(beamline BL17U)and the National Facility for Protein Science Shanghai(beamline BL19U)for assistance with X-ray data collection.We thank the KEK Photon Factory(beamline BL1A)and staff members for their assistance in X-ray data collection.We thank the Core Facilities at the School of Life Sciences,Peking University,for help with negative-staining EM.This project was supported by the Ministry of Science and Technology of China(2020YFC0848700)and the Qidong-SLS Innovation Fund to X.-D.S.This project was also supported by the Beijing Science and Technology Project(Z211100002521018);the National Natural Science Foundation of China(82073621,32070678);the National Key R&D Program of China(2021YFC0863300)to Y.-C.W.Special thanks to Drs.Sunney Xie,Junyu Xiao,Yunlong Cao for providing plasmids and IgG samples of the antibodies.; Dear Editor,SARS-CoV-2 variants are developing rapidly among COVID-19 patients,likely resulting in higher transmissibility at the population level.^(1,2,3,4,5) Mutations in the spike proteins(S proteins)of these varia...; 关键词：invasion alterations RBD

Ising Superconductivity and Its Hidden Variants: 《Accounts of Materials Research》2021年第7期526-533,共8页Chong Wang Yong Xu Wenhui Duan; supported by the Basic Science Center Project of NSFC(Grant No.51788104);the Ministry of Science and Technology of China(Grants No.2016YFA0301001,2018YFA0307100,and 2018YFA0305603);the National Science Fund for Distinguished Young Scholars(Grant No.12025405);the National Natural Science Foundation of China(Grant No.11874035);the Beijing Advanced Innovation Center for Future Chip(ICFC).; CONSPECTUS:The magnetic field usually suppresses superconductivity.Especially,at the critical magnetic field,superconductivity is destroyed.Ising superconductivity is a mechanism where the spin−orbit coupling signif...; 关键词：BANDS SUPERCONDUCTIVITY ISING

Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines被引量：21: 《Cell Research》2021年第7期732-741,共10页Yunlong Cao Ayijiang Yisimayi Yali Bai Weijin Huang Xiaofeng Li Zhiying Zhang Tianjiao Yuan Ran An Jing Wang Tianhe Xiao Shuo Du Wenping Ma Liyang Song Yongzheng Li Xiang Li Weiliang Song Jiajing Wu Shuo Liu Xuemei Li Yonghong Zhang Bin Su Xianghua Guo Yangyang Wei Chuanping Gao Nana Zhang Yifei Zhang Yang Dou Xiaoyu Xu Rui Shi Bai Lu Ronghua Jin Yingmin Ma Chengfeng Qin Youchun Wang Yingmei Feng Junyu Xiao Xiaoliang Sunney Xie; supported by Beijing Advanced Innovation Center for Genomics at Peking University and the Ministry of Science and Technology of China(2020YFC0848700).; SARS-CoV-2 variants could induce immune escape by mutations on the receptor-binding domain(RBD)and N-terminal domain(NTD).Here we report the humoral immune response to circulating SARS-CoV-2 variants,such as 501Y.V2(B...; 关键词：vaccines doses markedly

MosaicBase:A Knowledgebase of Postzygotic Mosaic Variants in Noncancer Disease-related and Healthy Human Individuals被引量：2: 《Genomics, Proteomics & Bioinformatics》2020年第2期140-149,共10页Xiaoxu Yang Changhong Yang Xianing Zheng Luoxing Xiong Yutian Tao Meng Wang Adam Yongxin Ye Qixi Wu Yanmei Dou Junyu Luo Liping Wei August Yue Huang; supported by grants from the National Natural Science Foundation of China(Grant No.31530092);the Ministry of Science and Technology of China(Grant No.2015AA020108)awarded to LW; Mosaic variants resulting from postzygotic mutations are prevalent in the human genome and play important roles in human diseases.However,except for cancer-related variants,there is no collection of postzygotic mosaic...; 关键词：POSTZYGOTIC MOSAICISM Noncancer Mutation MosaicBase

Threshold for neural tube defect risk by accumulated singleton loss-of-function variants被引量：7: 《Cell Research》2018年第10期1039-1041,共3页Zhongzhong Chen Yunping Lei Yufang Zheng Vanessa Aguiar-Pulido M. Elizabeth Ross Rui Peng Li Jin Ting Zhang Richard H. Finnell Hongyan Wang; We thank the families for their participation in this study. Data analysis and computing resource were supported by Center for Big Data Research in Health, Institute of Biophysics, Chinese Academy of Sciences. This proiect was supported by the National Key Basic Research Program of China （2016YFC1000502）, the National Natural Science Foundation of China （81430005, 31521003, 31771669, 81741048）, and the Commission for Science and Technology of Shanghai Municipality （17JC1400902） to H.W. and Y.Z.; and NIH （HD081216, HD083809, and HD067244） to R.H.F. and M.E.R.; Dear Editor, Neural tube defects （NTDs） are a class of major structural malformations affecting the brain and spinal cord. They are among the most common congenital anomalies with a worldwide prevalence of 0.1%.1,2...; 关键词：试管神经积累阈值风险变体世界范围 NTD

Variants of genes encoding collagens and matrix metalloproteinase system increased the risk of aortic dissection被引量：5: 《Science China(Life Sciences)》2017年第1期57-65,共9页Zongzhe Li Chengming Zhou Lun Tan Peng Chen Yanyan Cao Chenze Li Xianqing Li Jiangtao Yan Hesong Zeng Dao-Wu Wang Dao-Wen Wang; supported by the National Natural Science Foundation of China(91439203);National Key Basic Research Program of China(2012CB518004,2012CB517801); Aortic dissection （AD） is a devastating, heterogeneous condition of aorta. The homeostasis between collagens and matrix metalloproteases （MMPs）/tissue inhibitors of MMPs （TIMPs） system in the extracellular matri...; 关键词：aortic dissection COLLAGEN matrix metalloproteinase next-generation sequencing genetic diagnosis

Diversified variants of the mcr-1-carrying plasmid reservoir in the swine lung microbiota被引量：3: 《Science China(Life Sciences)》2016年第9期971-973,共3页Zhencui Li Chen Tan Jingxia Lin Youjun Feng; supported by the National Basic Research Program of China(2016YFC1200100);Zhejiang Provincial Natural Science Foundation for Distinguished Young Scholars(LR15H-190001);the National Natural Science Foundation of China(31570027);the start-up package from Zhejiang University(Youjun Feng);Dr.Feng is a recipient of the"Young 1000 Talents"Award; Dear Editor,Emergence of bacteria with multiple drug resistance is a major problem in global public health.Polymyxin comprising polymyxin E（colistin）and polymyxin B is generally recognized as the last-resort antibio...; 关键词：多元化微生物多粘菌素E 变异质粒肺部多粘菌素B 公共卫生

The schizophrenia/bipolar disorder candidate gene GNB1L is regulated in human temporal cortex by a cis-acting element located within the 3'-region被引量：2: 《Neuroscience Bulletin》2015年第1期43-52,共10页Yue Sun Yu Tao Jian Wang David Saffen; supported by the 985 Program of Ministry of Education,China;the National Basic Research Development Program(973 Program)of China(2009CB522007 and 2010CB529601);the National Natural Science Foundation of China(30870899 and 81070908); 22q 11.2 deletion syndrome（DS） is a complex developmental disorder with a high incidence of psychiatric illnesses,including schizophrenia and mood disorders.Recent studies have identified Guanine Nucleotide Binding ...; 关键词：GNB1L schizophrenia linkage disequilibrium eQTLs cis-regulatory variants

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

VARIANTS

检索结果分析

下载全文

高级检索检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

VARIANTS

检索结果分析

下载全文

用户登录

高级检索检索式检索