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作品数：191被引量：560H指数：12
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Direct infection of SARS-CoV-2 in human iPSC-derived 3D cardiac organoids recapitulates COVID-19 myocarditis被引量：2
《Virologica Sinica》2023年第6期971-974,共4页Weijie Wang Jinxuan Yang Pinfang Kang Jinsong Bai Xiaoli Feng Liuqi Huang Yiming Zhang Yuechun Wu Bi Tang Hongju Wang JianJie Jiang Minghua Li Bing Zhao Xinglou Yang 
Dear editor,The pandemic of coronavirus disease-19(COVID-19)has lasted for more than three years,causing lots of extra death and posing a serious threat to public health.This pandemic swept the last global safety isla...
关键词：CARDIOVASCULAR MORTALITY acute 
Hybridoma-derived neutralizing monoclonal antibodies against Beta and Delta variants of SARS-CoV-2 in vivo
《Virologica Sinica》2023年第2期257-267,共11页Qianran Wang Lu Peng Yanqiu Nie Yanni Shu Huajun Zhang Zidan Song Yufeng Li Hengrui Hu Liushuai Li Xi Wang Jia Liu Jiang Li Zhengli Shi Fei Deng Yu Guo Yiwu Zhou Bing Yan Zhihong Hu Manli Wang 
supported by grants from the National Key R&D Program of China(2021YFC2301700);National Natural Science Foundation of China(82061138021);the Key Biosafety Science and Technology Program of Hubei Jiangxia Laboratory(JXBS001);Hubei Natural Science Foundation for Distinguished Young Scholars(2021CFA050).
Neutralizing monoclonal antibodies(mAb)are a major therapeutic strategy for the treatment of severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)infection.The continuous emergence of new SARS-CoV-2 variants wor...
关键词：COVID-19 SARS-CoV-2 B.1.351 B.1.617.2 Monoclonal antibody 
Dynamic Host Immune and Transcriptomic Responses to Respiratory Syncytial Virus Infection in a Vaccination-Challenge Mouse Model被引量：1
《Virologica Sinica》2021年第6期1327-1340,共14页Yu Zhao Chen Ma Jie Yang Xiufen Zou Zishu Pan 
This work was supported by the National key R&D program of China(2017YFA0505801);the National Natural Science Foundation of China(11831015)。
Respiratory syncytial virus(RSV) is the major cause of lower respiratory tract infections in children. Inactivated RSV vaccine was developed in the late 1960’s, but the vaccine-enhanced disease(VED) occurred to vacci...
关键词：Respiratory syncytial virus(RSV) Vaccine enhanced disease(VED) Transcriptome analysis Regulatory networks 
Productive HBV infection of well-differentiated, hNTCP-expressing human hepatoma-derived(Huh7) cells被引量：7
《Virologica Sinica》2017年第6期465-475,共11页Ming Zhou Kaitao Zhao Yongxuan Yao Yifei Yuan Rongjuan Pei Yun Wang Jizheng Chen Xue Hu Yuan Zhou Xinwen Chen Chunchen Wu 
supported by the National Natural Science Foundation of China (Grant number: 81601760, 31621061 and 81461130019);General Financial Grant from the China Postdoctoral Science Foundation (Grant number: 2016M602587);the Shenzhen Foundation of Science and Technology (Grant number: JCYJ20160425 104534335);supported by the Youth Innovation Promotion Association CAS (No.201603)
Feasible and effective cell models for hepatitis B virus(HBV) infection are required for investigating the complete lifecycle of this virus, including the early steps of viral entry. Resistance to dimethyl sulfoxide/p...
关键词：Hepatitis B virus(HBV) Na+/taurocholate cotransporting polypeptide(NTCP) HUH7 dimethyl sulfoxide(DMSO) polyethylene glycol(PEG) susceptibility 
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