3T3-L1

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MiR-324-5p可能通过靶向淀粉样前体蛋白抑制棕榈酸诱导的3T3-L1脂肪细胞凋亡
《中国生物化学与分子生物学报》2020年第8期917-923,共7页王杰 周小敏 杜天宁 刘捷明 史新娥 
国家重点基础研究发展(973计划)项目(No.2015CB943102)资助。
miRNAs是一种非编码的小RNA,通过靶向mRNA的3′UTR调控基因的转录后翻译。为明确miR-324-5p对棕榈酸诱导的3T3-L1脂肪细胞凋亡的作用和机制,体外培养3T3-L1脂肪细胞,利用棕榈酸诱导细胞凋亡的同时过表达或抑制miR-324-5p,通过Annexin-V/...
关键词：miR-324-5p 3T3-L1脂肪细胞 凋亡 淀粉样前体蛋白 
Effect of diacylglycerol acyltransferase 2overexpression in 3T3-L1 is associated to an increase in mono-unsaturated fatty acid accumulation被引量：3
《Journal of Animal Science and Biotechnology》2014年第4期406-413,共8页Zhiqi Zhang Gang Shu Xiaotong Zhu Junming Guo Han Cai Songbo Wang Lina Wang Ping Gao Qianyun Xi Yongliang Zhang Li Yuan Qingyan Jiang 
supported by grants from the National Basic Research Program of China-the 973 Program(2012CB124701;2013CB127306);the Talent Project of guangdong colleges;the Natural Science Foundation of Guangdong Province of China(S2012020011048);the Research Fund for the Doctoral Program of Higher Education
Background：Fatty acid（FA） composition is the most important parameter affecting the flavor and nutritional value of the meat.The final and the only committed step in the biosynthesis of triglycerides is catalyzed b...
关键词：DGAT2 Fatty acid composition Overexpressing Pig 
Cryo-copolymerization preparation of dextran-hyaluronate based supermacroporous cryogel scaffolds for tissue engineering applications被引量：1
《Frontiers of Chemical Science and Engineering》2012年第3期339-347,共9页Dongjiao ZHOU Shaochuan SHEN Junxian YUN Kejian YAO Dong-Qiang LIN 
Acknowledgements This work was supported by the National Natural Science Foundation of China （Grant Nos. 20876145, 21036005）, the Science and Technology Cooperation Project between China-Europe Country＇s Governments from the Ministry of Science and Technology of China （No. 1017） and the Zhejiang Provincial Natural Science Foundation of China （No. Y4080326）.
Dextran-hyaluronate （Dex-HA） based supermacroporous cryogel scaffolds for soft tissue engineering were prepared by free radical cryo-copolymerization of aqueous solutions containing the dextran methacrylate （Dex-MA...
关键词：cryogel scaffold tissue engineering dextran hyaluronate 3T3-L1 preadipocyte 
The role of Akt on Arsenic trioxide suppression of 3T3-L1 preadipocyte dif-ferentiation被引量：5
《Cell Research》2005年第5期379-386,共8页ZhiXinWANG ChunSunJIANG LeiLIU XiaoHuiWANG HaiJingJIN QiaoWU QuanCHEN 
This work is supported by grants from National Nature Science Foundation of China(No.30000083);Quan.CHEN's laboratory was supported by grants“Knowledge Innovation Key Project"(kscx2-sw-2010)of Chinese Academy of Sciences;the National Basic Research Program of China(973 program project,No.2002CB5 13 100);National Fund for Outstanding Young Scholars from NSFC(30325013)awarded to Quan CHEN.
The present study investigates the molecular details of how arsenic trioxide inhibits preadipocyte differentiation and examines the role of Akt/PKB in regulation of differentiation and apoptosis. Continual exposure of...
关键词：PREADIPOCYTE cell differentiation apoptosis AKT/PKB Arsenic trioxide. 
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