PREADIPOCYTE

作品数：21被引量：106H指数：6
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相关领域：医药卫生生物学更多>>
相关作者：张崇本顾军金军华滕路尚克刚更多>>
相关机构：北京大学北京医院中国农业科学院四川农业大学更多>>
相关期刊：《Genes & Diseases》《Acta Biochimica et Biophysica Sinica》《Progress in Natural Science:Materials International》《Frontiers of Chemical Science and Engineering》更多>>
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m^(6)A demethylase FTO regulate CTNNB1 to promote adipogenesis of chicken preadipocyte
《Journal of Animal Science and Biotechnology》2023年第2期578-592,共15页Kan Li Weichen Huang Zhijun Wang Qinghua Nie 
funded by the Natural Scientific Foundation of China(U1901206);Local Innovative and Research Teams Project of Guangdong Province(2019BT02N630);the Science and Technology Program of Guangdong province,China(2020B1212060060);the Science and Technology Program of Guangzhou,China(202103000084);the Construction Project of Modern Agricultural Science and Technology Innovation Alliance in Guangdong Province(2021KJ128);National Key R&D Program of China(2021YFD1300100);China Agriculture Research System(CARS-41-G03).
Background:N6-methyladenosine(m^(6)A)is an abundant post-transcriptional RNA modification that affects various biological processes.The fat mass and obesity-associated(FTO)protein,a demethylase encoded by the FTO gene...
关键词：ADIPOGENESIS CHICKEN CTNNB1 FTO m^(6)A 
PU.1 interacts with KLF7 to suppress differentiation and promote proliferation in chicken preadipocytes
《Acta Biochimica et Biophysica Sinica》2023年第1期143-153,共11页Ming Tan Hu Xu Jinwei Li Ziqiu Jia Xin Zhang Shuli Shao Weiwei Zhang Weiyu Wang Yingning Sun 
This work was supported by the grants from the National Natural Science Foundation of China(No.31402061);the Heilongjiang Province Natural Science Foundation of China(No.YQ2019C025);the Project of the Basic Business of Heilongjiang Provincial Education Department(No.145109211).
Krüppel-like factor 7(KLF7)is a negative regulator of preadipocyte differentiation.Our previous KLF7 ChIP-seq analysis showed that the binding motif of PU.1 was found among the KLF7 binding peaks,indicating that an i...
关键词：PU.1 PREADIPOCYTE KLF7 DIFFERENTIATION PROLIFERATION 
KLF7 promotes preadipocyte proliferation via activation of the Akt signaling pathway by Cis-regulating CDKN3被引量：4
《Acta Biochimica et Biophysica Sinica》2022年第10期1486-1496,共11页Ziqiu Jia Zhao Jin Shuli Shao Hu Xu Wen Li Mahmood Khan Weiyu Wang Weiwei Zhang Yingning Sun 
supported by the grants from the National Natural Science Foundation of China(No.31402061);the Heilongjiang Provincial Natural Science Foundation of China(No.YQ2019C025);the Program of Graduate Student Innovation and Scientific Research(No.YJSCX2020043);the Project of the Basic Business of Heilongjiang Provincial Education Department(No.YSTSXK201875).
Krüppel-like transcription factor 7(KLF7)promotes preadipocyte proliferation;however,its target gene in this process has not yet been identified.Using KLF7 ChIP-seq analysis,we previously showed that a KLF7-binding p...
关键词：PROLIFERATION cyclin-dependent kinase inhibitor 3 Krüppel-like transcription factor 7 Akt signaling pathway PREADIPOCYTE 
N^(6)-methyladenosine demethylase ALKBH5:a novel regulator of proliferation and differentiation of chicken preadipocytes被引量：2
《Acta Biochimica et Biophysica Sinica》2022年第1期55-63,共9页Qi Zhang Bohan Cheng Haixu Jiang Huili Zhang Hui Li 
This work was supported by the grants from the National Natural Science Foundation(No.31902142);the China Agriculture Research System of MOF and MARA(No.CARS-41).
Previous studies have reported that the N^(6)-methyladenosine demethylase ALKBH5 can regulate adipogenesis in humans.However,its function in birds remains unclear.In this study we aimed to explore the expression and f...
关键词：ALKBH5 CHICKEN PREADIPOCYTE proliferation DIFFERENTIATION 
A genome-wide landscape of mRNAs,lncRNAs,and circRNAs during subcutaneous adipogenesis in pigs被引量：8
《Journal of Animal Science and Biotechnology》2019年第1期43-55,共13页Xin Liu Kaiqing Liu Baosen Shan Shengjuan Wei Dongfeng Li Haiyin Han Wei Wei Jie Chen Honglin Liu Lifan Zhang 
supported by the National Transgenic Project of China(2018ZX0800928B);the National Key Technology Research and Development Program of the Ministry of Science and Technology of China(2015BAD03B01);the National Natural Science Foundation of China(31501930)
Background: Preadipocyte differentiation plays a critical role in subcutaneous fat deposition in pigs.However,the roles of different RNAs,such as messenger RNAs(mRNAs),long non-coding RNAs(lncRNAs),and circular RNAs(c...
关键词：CircRNA LncRNA mRNA Pig PREADIPOCYTE differentiation RNA-Seq 
Synthesis and evaluation of benzylisoquinoline derivatives for their inhibition on pancreatic lipase and preadipocyte proliferation被引量：1
《Chinese Journal of Natural Medicines》2016年第5期382-390,共9页TIAN Feng LV Hao-Yu ZOU Ji-Long WANG Yi DUAN Meng-Jun CHU Xiao-Qin LI Dan ZHU Liang JIANG Jian-Qin 
supported by the Graduate Students Scientific Research Innovation Projects of Jiangsu Province(No:CXZZ11-0804)
The present study was designed to synthesize and evaluate a series of benzylisoquinoline derivatives. These compounds were synthesized by Bischler-Napieralski cyclization to yield 1-benzyl-3,4-dihydroisoquinolines, an...
关键词：Nelumbo nucifera Benzylisoquinoline alkaloid ANTI-OBESITY Pancreatic lipase inhibitor Adipocyte proliferation 
Higher Cell Viability and Enhanced Sample Quality Following Laser-Assisted Liposuction versus Mechanical Liposuction
《Journal of Cosmetics, Dermatological Sciences and Applications》2015年第3期238-245,共8页Alexander Levenberg Mickey Scheinowitz Orna Sharabani-Yosef 
Background: Despite the popularity of autologous fat transfer applications, high resorption rates, and consequential volume loss, have been reported. Viable adipocyte content has been defined as a key determinant of f...
关键词：LASER LIPOSUCTION Cell VIABILITY FAT Transfer PREADIPOCYTE 
The thermogenic circuit: Regulators of thermogenic competency and differentiation
《Genes & Diseases》2015年第2期164-172,共9页Matthew D.Lynes Yu-Hua Tseng 
This work was supported in part by National Institutes of Health(NIH)Grant(R01DK077097);Joslin Diabetes Center’s Diabetes Research Center(P30DK03836);a research grant from the American Diabetes Foundation(ADA 7-12-BS-191);by funding from the Harvard Stem Cell Institute(to Y-H.T).M.D.L was supported by NIH fellowships(T32DK007260 and F32DK102320).
In mammals,a thermogenic mechanism exists that increases heat production and consumes energy.Recent work has shed light on the cellular and physiological mechanisms that control this thermogenic circuit.Thermogenicall...
关键词：ADIPOGENESIS Autologous transplants Brown adipose tissue Cell therapy UCP1 OBESITY PREADIPOCYTE THERMOGENESIS 
MicroRNA-125b-5p inhibits proliferation and promotes adipogenic differentiation in 3T3-L1 preadipocytes被引量：10
《Acta Biochimica et Biophysica Sinica》2015年第5期355-361,共7页Dan Ouyang Yaqiong Ye Dongguang Guo Xiaofang Yu Jian Chen Junjie Qi Xiaotong Tan Yuan Zhang Yongjiang Ma Yugu Li 
This work was supported by a grant from the National Natural Science Foundation of China （No. 31272519）.
Previous evidence has indicated that the microRNA-125b （miR-125b） family plays important roles in the regulation of cancer cell growth, development, differentiation, and apoptosis. However, whether they contribute t...
关键词：microRNA miR-125b-5p SMAD4 3T3-L1 preadipocyte DIFFERENTIATION 
Dose-related effects of sericin on preadipocyte behavior within collagen/sericin hybrid scaffolds
《Progress in Natural Science:Materials International》2015年第2期122-130,共9页Valentina Mitran Madalina Georgiana Albu Eugeniu Vasile Anisoara Cimpean Marieta Costache 
supported by Romanian CNCS–UEFISCDI, Complex Exploratory Research Project (Grant no. PCCE248/2010)
This paper aims at demonstrating the biocompatibility of recently developed 3D hydrogel scaffolds containing the same amount of collagen(COLL) and variable concentrations of sericin(SS) in order to find the most suita...
关键词：Sericin–collagen SCAFFOLD PREADIPOCYTE PROLIFERATION Morphology Tissue engineering 
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