the National Key Research and Development Program of China(No.2021YFA0909900);the National Natural Science Foundation of China(Nos.82073777 and 81803442);the General Project of Liaoning Provincial Department of Education(Nos.LJKZ0927 and LJKQZ2021034);the Natural Science Foundation of Liaoning Province(No.2022-BS-157).
Despite great therapeutic effect of Abraxane®,complex preparation technology and unfavorable pharmacokinetics still restricted the clinical application of albumin-based paclitaxel(PTX)nanoparticles(NPs).Herein,we repo...
supported by National Natural Science Foundation of China(No.81773656 and U1608283);Liaoning Revitalization Talents Program(No XLYC1808017,China);Key projects of Technology bureau in Shenyang(No.18400408,China);Key projects of Liaoning Province Department of Education(No.2017LZD03,China);111 Project(D20029,China)
A commercial albumin-bound paclitaxel nano-formulation has been considered a gold standard against breast cancer.However,its application still restricted unfavorable pharmacokinetics and the immunogenicity of exogenou...
Background: The purpose of this study is to evaluate the clinical efficacy and safety of abraxane-based chemotherapy with/without nedaplatin in elderly patients with non-small-cell lung cancer (NSCLC). Materials an...