云南高校图书馆联盟文献共享服务平台- ANTIRETROVIRAL

ANTIRETROVIRAL: 作品数：130被引量：144H指数：7; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：李玉枝唐漾波杨涤曾辉赵红心更多>>; 相关机构：广州市第八人民医院北京大学北京地坛医院昆明医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金World Health Organization国家重点基础研究发展计划艾滋病和病毒性肝炎等重大传染病防治专项更多>>

Sunlenca■(Lenacapavir):A first-in-class,long-acting HIV-1 capsid inhibitor for treating highly multidrug-resistant HIV-1 infection: 《Acta Pharmaceutica Sinica B》2024年第12期5512-5514,共3页Chunhua Ma Junbiao Chang Bin Yu; support from the National Natural Science Foundation of China(Nos.22277110 and 82003585)and Tianjian Laboratory of Advanced Biomedical Sciences.; Lenacapavir,also known as GS-6207,under the brand name Sunlenca,was developed by Gilead Sciences Inc.It has been approved in the EU,Canada,and US for use alongside other antiretrovirals in adults with multidrug-resist...; 关键词：Lenacapavir Capsid inhibitor HIV-1 infection HIV prevention Multidrug resistance Antiretroviral medication

Corrigendum:Pre-existing low-frequency resistance mutations increase the risk of antiretroviral treatment failure in HIV-1 naïve patients: 《Chinese Medical Journal》2024年第7期882-882,共1页; The authors declare that in the correspondence“Preexisting low-frequency resistance mutations increase the risk of antiretroviral treatment failure in HIV-1 naïve patients”[1]which was published in vol.136,issue 22,...; 关键词：PATIENTS Medical treatment

Factors Associated with HIV/Tuberculosis Coinfection among People Living with HIV after Initiation of Antiretroviral Treatment in Lingwala Health Zone from 2021 to 2023: 《Advances in Infectious Diseases》2024年第1期176-195,共20页Jean Claude Mikobi Maleshila Espérant Ntambue Malu Fabrice Sewolo Tacite Kpanya Mazoba Jean Nyandwe Kyloka; Context and objective: Around 8% of incident cases of tuberculosis (TB) were reported among people living with HIV worldwide in 2022. Tuberculosis is the leading cause of death among people living with HIV. Africa acc...; 关键词：PLHIV on ART HIV/TB Co-Infection Viral Load Antiretroviral (ARV) Adherence

Pre-existing low-frequency resistance mutations increase the risk of antiretroviral treatment failure in HIV-1 naïve patients: 《Chinese Medical Journal》2023年第22期2756-2758,共3页Yifan Su Rentian Cai Yinyin Zhu Mingli Zhong Mingxue Qi Chen Chen Zi Ye Hongying Zhang Hongxia Wei; supported by the 2020 Annual Medical Research Project of Jiangsu Commission of Health(No.ZDA 2020014);the Key Project supported by Medical Science and Technology Development Foundation,Nanjing Department of Health(Nos.ZKX 22040 and ZKX 19048); To the Editor:High-frequency resistance(typically≥15-25%viral quasispecies)detected by conventional resistance assays has long been associated with failure of antiretroviral therapy(ART)to suppress viral replication,...; 关键词：PATIENTS resistance REGIMEN

Dolutegravir plus lamivudine versus dolutegravir plus tenofovir disoproxil fumarate and emtricitabine in antiretroviral-naive adults with HIV-1 infection(GEMINI-1 and GEMINI-2):week 48 results from two multicentre,double-blind,randomised,non-inferiority,phase 3 trials: 《四川生理科学杂志》2023年第10期1852-1852,共1页Pedro Cahn; Background:Effective two-drug regimens could decrease long-term drug exposure and toxicity with HIV-1 antiretroviral therapy(ART).We therefore aimed to evaluate the efficacy and safety of a two-drug regimen compared w...; 关键词：regimen infection centre

Polypeptides inhibit HIV-1 replication by interfering viral Vpu-mediated tetherin degradation: 《Infectious Medicine》2023年第3期224-228,共5页Shuai Chang Lifeng Cai Yongchang Yang Binlian Sun Jingyun Li Jie Liu Lin Li; Background:HIV-1 Vpu acts by counteracting the tethering function of tetherin and resulting in the release of HIV-1 virion.Disrupting Vpu-tetherin interactions may provide a promising new target for antiretroviral the...; 关键词：ANTIRETROVIRAL HIV-1 POLYPEPTIDE VPU TETHERIN

Analysis of Knowledge Level and Use of Antiretroviral Pre-Exposure and Post-Exposure Prophylaxis Among MSM—China,2019–2022被引量：4: 《China CDC weekly》2023年第13期292-296,共5页Jiahuan Guo Wenting Kang Tongtong Liu Jie Xu Houlin Tang Fan Lyu Guang Zhang; Summary What is already known on this topic?Men who have sex with men(MSM)in China have a high rate of human immunodeficiency virus(HIV)infection.Pre-exposure prophylaxis(PrEP)and postexposure prophylaxis(PEP)have bee...; 关键词：PREVENTION MSM IMMUNODEFICIENCY

Optimal control of combined antiretroviral therapies in an HIV infection model with cure rate and fusion effect被引量：2: 《International Journal of Biomathematics》2023年第1期29-51,共23页Bhagya Jyoti Nath Kaushik Dehingia Khadijeh Sadri Hemanta Kumar Sarmah Kamyar Hosseini Choonkil Park; This paper mainly targets to deduce an optimal treatment strategy for combined antiretroviral drugs,which can maximize healthy CD4^(+)T cells level with minimum side effects and cost.For this purpose,we consider a wit...; 关键词：HIV infection antiretroviral drugs critical efficacy optimal control Pontryagin's maximum principle.

Pre-treatment Drug Resistance Could Impact the 96-Week Antiretroviral Efficacy in Treatment-Naive HIV-1–Infected Patients in Guangdong,China被引量：1: 《Infectious Diseases & Immunity》2022年第4期233-238,共6页Pengle Guo Yun Lan Quanmin Li Xuemei Ling Junbin Li Xiaoping Tang Fengyu Hu Weiping Cai Linghua Li; supported by the Major National Science and Technology Projects during the 13th 5-year plan period(2017ZX10202101-003,2017ZX10202102-003-004);the Guangzhou Science and Technology Innovation Committee project(new strategy for functional cure of AIDS–clinical and basic research,201803040002);Guangzhou basic research program on people’s Livelihood Science and technology(No.202002020005).; Background:With the high prevalence of pre-treatment drug resistance(PDR)and the potential impact to the virological inhibition,the detection of PDR was particularly necessary.This study aimed to determine the prevale...; 关键词：Prevalence Pretreatment drug resistance Antiretroviral therapy Virologic failure

Persistently low CD4 cell counts are associated with hepatic events in HCV/HIV coinfected patients: data from the national free antiretroviral treatment program of China被引量：2: 《Chinese Medical Journal》2022年第22期2699-2705,共7页Weiyin Lin Huolin Zhong Chunyan Wen Yaozu He Xiaowen Zheng Hong Li Xiejie Chen Haolan He Jinfeng Chen Lijuan Chen Cong Liu Xiaoping Tang Weiping Cai Linghua Li; Guangzhou Basic Research Program on People’s Livelihood Science and Technology(No. 202002020005);National Natural Science Foundation of China(No. 82072265);Chinese 13th Five-Year National Science and Technology Major Project(No. 2017ZX10202101-003-001)。; Background: Chronic liver disease has emerged as a leading cause of non-acquired immune deficiency syndrome (AIDS)-related mortality in hepatitis C virus (HCV)/human immunodeficiency virus (HIV)-coinfected patients. T...; 关键词：CD4 cell count CO-INFECTION Hepatic events Hepatitis C virus Human immunodeficiency virus

ANTIRETROVIRAL