Supported by the Genetically Modified Organisms Breeding Major Project of China(No.2009ZX08006-002B);the National Natural Science Foundation of China(Nos.81101140,81072210);the Key Technologies Research and Development Program of Jilin Province,China(Nos.10ZDGG007,201015166);the China Postdoctoral Science Foundation Funded Project(No.20100481057)
We investigated the anti-tumor effects of dual cancer specific-oncolytic adenovirus Ad-VP on esophageal cancer(EC). The anti-tumor activity of Ad-VP was compared with that of the control recombinant adenoviruses (A...
Supported by the National High-Tech Research and Development Program of China(No.2007AA021004);the National Basic Research Program of China(No.2005CB523005);the National Science and Technology Major Project of China (Nos.2008ZX10004-015,2009ZX08006-002B);the National Natural Science Foundation of China(No.30771609)
Apoptin is a chicken anemia virus-derived,p53-independent,bcl-2-insensitive apoptotic protein with the ability to specifically induce apoptosis of various human tumor cells,but not of normal diploid cells.To explore t...
The chicken anemia virus protein, apoptin, which manifests selectivity and specificity to tumor cells, induces a p53-independent and Bcl-2-insensitive type of apoptosis in various human tumor cells. In this study, the...