This study was supported by grants from the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)to FA(AR 1092/2-2)and to KA/CD(SFB 1350,project number 387509280).
Treatment with aprotinin,a broad-spectrum serine protease inhibitor with a molecular weight of 6512 Da,was associated with acute kidney injury,which was one of the reasons for withdrawal from the market in 2007.Inhibi...
Redo cardiac surgery increases?mortality and morbidity. The aim of this study was to determine if aprotinin was superior to tranexamic acid concerning control bleeding loss after redo valve surgery. A retrospective st...
An analysis of selected datasets from the FDA’s drug Adverse Event Reporting System (FAERS) leads us to hypothesize that glyphosate contamination in both food and drugs is a major contributor to chronic and acute kid...
ObjectiveTo explore the protective effect of aprotinin contained LPD (low potassium dextran) solution via an in situ rabbit lung preservation model.MethodsThirty New Zealand rabbits were divided randomly into 3 groups...
Grant 02KJD320015 from the Education Committee of Jiangsu Province, China
AIM:To study the effect of aprotinin used in orthotopic liver transplantation (OLT) on the intraoperative requirement for blood products and on the incidence of laparotomy for bleeding, thrombotic events and mortality...
To explore the influence of aprotinin on the mRNA expression of P-selectin and ICAM-1 in lung tissue after ischemic reperfusion.Methods Thirty New Zealand white rabbits were randomly divided into 3 groups:control grou...
Objective: To investigate the role of aprotinin blood anesthesia used in hepatotomy. Methods: Patients with liver cancer undergoing hepatotomy were divided into two groups. In experimental group (40 patients) a loadin...
OBJECTIVE: To explore platelet activation and the protective effect of aprotinin in patients with hepatolithiasis. METHODS: The count of plaletets and levels of CD_(62P) and CD_(63) were measured by flow cytometry in ...
Supported by the Jiangsu Health Bureau Grand (B9606)
Objective To investigate the effects of the topical use of aprotinin on thebasis of comprehensive blood conservations in cardiopulmonary bypass (CPB). Methods In a prospectiveclinical trial, 20 patients were randomly ...