supported by the Taishan Scholar Foundation of Shandong Province(No.tsqn202211065);Hainan Provincial Joint Project of Sanya Yazhou Bay Science and Technology City(No.2021JJLH0037);the Natural Science Foundation of China(No.82003673);the Fundamental Research Funds for the Central Universities(No.202113049)。
Early pathogenesis of ischemia-reperfusion(I/R)-induced acute kidney injury(AKI)is dominated by intracellular calcium overload,which induces oxidative stress,intracellular energy metabolism disorder,inflammatory activ...