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BET: 作品数：551被引量：1396H指数：14; 导出分析报告; 相关领域：理学更多>>; 相关作者：张惠斌陈亚东陆涛朱承飞吉光辉更多>>; 相关机构：中国药科大学中南大学中国科学院大学华中科技大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金国家高技术研究发展计划更多>>

BET基因功能及其抑制剂在COPD中的作用: 《生命的化学》2025年第4期633-645,共13页郭亮生王帅关程丹高晓吴斌; 广东省基础与应用基础研究基金项目(2023A1515012298)。; 溴结构域和额外末端结构域(bromodomain and extra-terminal domain,BET)蛋白家族通过其溴结构域特异性识别组蛋白上的乙酰化赖氨酸残基,调控基因表达。BET抑制剂通过阻断BET蛋白与组蛋白的相互作用,抑制炎症相关基因的表达,展现出显著...; 关键词：溴结构域和额外末端结构域慢性阻塞性肺疾病抗炎抑制剂

Labeling-based centrality approaches for identifying critical edges on temporal graphs: 《Frontiers of Computer Science》2025年第2期89-104,共16页Tianming ZHANG Jie ZHAO Cibo YU Lu CHEN Yunjun GAO Bin CAO Jing FAN Ge YU; supported by the National Natural Science Foundation of China(Grant Nos.62302451 and 62276233);the Natural Science Foundation of Zhejiang Province of China(No.LQ22F020018);the Key Research Project of Zhejiang Province of China(No.2023C01048).; Edge closeness and betweenness centralities are widely used path-based metrics for characterizing the importance of edges in networks.In general graphs,edge closeness centrality indicates the importance of edges by th...; 关键词：temporal graph closeness centrality between-ness centrality temporal path

Post-streptococcal acute glomerulonephritis in children:Association between proteinuria levels and renal outcomes: 《World Journal of Clinical Pediatrics》2025年第1期119-126,共8页Randula Ranawaka Kavinda Dayasiri Udara Sandakelum Dulani Nelson Manoji Gamage; BACKGROUND Post-streptococcal acute glomerular nephritis(PSAGN)is mostly a benign condition.The usual sequelae of PSAGN include hypertension,its complications,and acute kidney injury.Severe PSAGN is associated with si...; 关键词：PROTEINURIA Post-streptococcal acute glomerulonephritis Renal outcome Renal biopsy Crescents Serum creatinine

Impact of the polydispersion of TiO_(2) materials on their particle size calculated from specific surface area results obtained during an interlaboratory comparison exercise: 《Particuology》2025年第3期31-40,共10页Sébastien Bau Sébastien Artous Sébastien Jacquinot Dominique Locatelli Jean-Francois Hochepied Nicolas Feltin Carine Chivas-Joly; In this work,four samples of TiO_(2) powder materials with different structures(rutile,anatase),surface coatings and morphologies(rod,pseudo-spherical)were characterized by four partners involving complementary method...; 关键词：Size measurement TiO_(2) BET NANOPARTICLE Volume specific surface area

Tacrolimus induces insulin receptor substrate 1 hyperphosphorylation and inhibits mTORc1/S6K1 cascade in HL7702 cells: 《World Journal of Diabetes》2025年第2期175-182,共8页Hao-Yan Li Yi Wang Min Ran Fei Gao Bo-Yu Zhu Hai-Ying Xiao Chun Xu; BACKGROUND Tacrolimus(FK506)is a key calcineurin inhibitor used to prevent organ transplant rejection and is effective in improving graft survival.However,it is linked to hyperglycemia and insulin resistance,contribut...; 关键词：TACROLIMUS Insulin resistance DYSLIPIDEMIA Ribosomal protein S6 kinase beta-1 Glucose metabolism

Rhythm Facilitates Auditory Working Memory via Beta-Band Encoding and Theta-Band Maintenance: 《Neuroscience Bulletin》2025年第2期195-210,共16页Suizi Tian Yu-Ang Cheng Huan Luo; supported by the National Natural Science Foundation of China(12171373);supported by the Fundamental Research Funds for the Central Universities of China(GK202207018).; Rhythm,as a prominent characteristic of auditory experiences such as speech and music,is known to facilitate attention,yet its contribution to working memory(WM)remains unclear.Here,human participants temporarily reta...; 关键词：RHYTHM Working memory Sensorimotor:Neural oscillation Drift diffusion model

Solid − liquid phase diagram of the KNO_(3) - Ca(NO_(3))_(2) - Mg(NO_(3))_(2) - H_(2)O system at 313.15 K: 《Chinese Journal of Chemical Engineering》2025年第2期93-107,共15页Xiangxia Zeng Tao Zhang Li Lv Wenxiang Tang Zongpeng Zou Shengwei Tang; support from the National Key Research and Development Program of China(2022YFC2904704);the Fundamental Research Funds for the Central Universities(SCU2024D009)。; The enrichment of low-grade phosphate rock is an important process to realize sustainable support of phosphorus resources. An aqueous solution containing Ca(NO_(3))_(2) and Mg(NO_(3))_(2) is produced during the enrich...; 关键词：Calcium nitrate Magnesium nitrate Liquid water-soluble fertilizer Phase equilibria BET model

Relationship Between General MP and DPP for the Stochastic Recursive Optimal Control Problem with Jumps: 《Journal of Systems Science & Complexity》2024年第6期2466-2486,共21页WANG Bin SHI Jingtao; supported by National Key Research and Development Program of China under Grant No.2022YFA1006104;the National Natural Science Foundations of China under Grant Nos.12471419 and 12271304;the Natural Science Foundation of Shandong Province under Grant No.ZR2022JQ01。; This paper is concerned with the relationship between general maximum principle and dynamic programming principle for the stochastic recursive optimal control problem with jumps,where the control domain is not necessa...; 关键词：Backward stochastic differential equation with jumps dynamic programming principle maximum principle recursive optimal control viscosity solution

温控型固体催化剂Bet_(n)H_(5-n)PMo_(10)V_(2)O_(40)在纤维素糖化中的催化性能: 《北华大学学报（自然科学版）》2024年第6期814-819,共6页齐宇王启文陈远楠李宗航段喜鑫王晓红时君友; 吉林省科技厅重点研发项目(20210203205SF);国家自然科学基金重点项目(32130073);吉林省自然科学基金项目(YDZJ202401409ZYTS)。; 纤维素是自然界中分布最广、储量最大的天然有机物,高效糖化是纤维素应用的基础,而催化剂设计是应用的关键。开发具有合适酸性质、高效、低成本的固体催化剂以可持续地从纤维素生产糖仍是巨大挑战。基于此,构建多金属氧酸盐(POMs)温控...; 关键词：纤维素多金属氧酸盐非均相催化高效糖化协同作用

ESPN Bet向体育博彩巨头发起挑战: 《商业周刊（中文版）》2024年第22期56-59,共4页Christopher Palmeri Brandon Mioduszewski 永年(译); 2023年夏天,ESPNInc.和赌场运营商Penn Entertainment Inc.宣布了一项为期10年、价值20亿美元的协议。Penn公司与媒体公司Barstool SportsInc.有合作关系,最终锚定了自称“世界体育领袖”的ESPN。Penn首席执行官杰伊·斯诺登(Jay Snowd...; 关键词：主要参与者体育博彩 ESPN 首席执行官电话会议分析师斯诺登

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