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作品数:243被引量:241H指数:7
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相关领域:医药卫生更多>>
相关作者:徐晓东张晓晖吕思琪卢冬陈锦娣更多>>
相关机构:清华大学南京师范大学北京航空航天大学对外经济贸易大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金上海市自然科学基金更多>>
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The eQTL colocalization and transcriptome‑wide association study identify potentially causal genes responsible for economic traits in Simmental beef cattle被引量:1
《Journal of Animal Science and Biotechnology》2023年第5期1909-1925,共17页Wentao Cai Yapeng Zhang Tianpeng Chang Zezhao Wang Bo Zhu Yan Chen Xue Gao Lingyang Xu Lupei Zhang Huijiang Gao Jiuzhou Song Junya Li 
supported by grants from the Central Public-interest Scientific Institution Basal Research Fund(2020-YWF-YB-02);the Young Scientists Fund of the National Natural Science Foundation of China(32202652);China Agriculture Research System of MOF and MARA(CARS-37);the Science and Technology Project of Inner Mongolia Autonomous Region(2020GG0210).
Background A detailed understanding of genetic variants that affect beef merit helps maximize the efficiency of breeding for improved production merit in beef cattle.To prioritize the putative variants and genes,we ra...
关键词:Cattle COLOCALIZATION eQTL mapping GWAS TWAS 
Construction of a transposase accessible chromatin landscape reveals chromatin state of repeat elements and potential causal variant for complex traits in pigs
《Journal of Animal Science and Biotechnology》2023年第2期529-545,共17页Tao Jiang Ziqi Ling Zhimin Zhou Xiaoyun Chen Liqing Chen Sha Liu Yingchun Sun Jiawen Yang Bin Yang Jianzhen Huang Lusheng Huang 
supported by National Key Research and Development Program of China(2021YFF1000601).
Background:A comprehensive landscape of chromatin states for multiple mammalian tissues is essential for elucidating the molecular mechanism underlying regulatory variants on complex traits.However,the genome-wide chr...
关键词:Chromatin accessibility Pig Tissue specific TRANSCRIPTOME Transposable elements 
Mapping short tandem repeats for liver gene expression traits helps prioritize potential causal variants for complex traits in pigs
《Journal of Animal Science and Biotechnology》2022年第3期707-720,共14页Zhongzi Wu Huanfa Gong Zhimin Zhou Tao Jiang Ziqi Lin Jing Li Shijun Xiao Bin Yang Lusheng Huang 
supported by National Natural Science Foundation of China(31790413);supported by National Natural Science Foundation of China(31760657)。
Background:Short tandem repeats(STRs)were recently found to have significant impacts on gene expression and diseases in humans,but their roles on gene expression and complex traits in pigs remain unexplored.This study...
关键词:Cis-eQTL CO-LOCALIZATION Gene expression LIVER Pig heterogeneous population Short tandem repeats 
A post-GWAS confirming the genetic effects and functional polymorphisms of AGPAT3 gene on milk fatty acids in dairy cattle被引量:3
《Journal of Animal Science and Biotechnology》2021年第1期122-140,共19页Lijun Shi Xin Wu Yuze Yang Zhu Ma Xiaoqing Lv Lin Liu Yanhua Li Feng Zhao Bo Han Dongxiao Sun 
financially supported by the National Natural Science Foundation of China (31872330, 31802041);Beijing Science and Technology Program (20200105, D171100002417001);earmarked fund for Modern Agroindustry Technology Research System (CARS-36);the Program for Changjiang Scholar and Innovation Research Team in University (IRT_15R62)。
Background: People are paying more attention to the healthy and balanced diet with the improvement of their living standards. Milk fatty acids(FAs) have been reported that they were related to some atherosclerosis and...
关键词:AGPAT3 Chinese Holstein Genetic effects Milk fatty acids Potential causal mutation 
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