Preterm birth(PTB),defined as a live birth occurring before 37 weeks of gestation,is associated with numerous adverse outcomes.These include poor growth,respiratory disorders,heightened susceptibility to infections be...
supported by the National Natural Science Foundation of China(No.82303169);the Key Research and Development Program of Shaanxi(No.2021ZDLSF02-06).
Objective Several epidemiological observational studies have related particulate matter(PM)exposure to Inflammatory bowel disease(IBD),but many confounding factors make it difficult to draw causal links from observati...
supported in part by the Interdisciplinary Research Foundation for Doctoral Candidates of Beijing Normal University(BNUXKJC2219).
Quantifying emergence and modeling emergent dynamics in a data-driven manner for complex dynamical systems is challenging due to the fact that emergent behaviors cannot be directly captured by micro-level observationa...
Type 2 diabetes is a chronic metabolic disorder, and the behavior and quantity of alcohol consumption may be influenced by genetic factors. Moderate alcohol consumption has been associated with a reduced risk of type ...
This work was supported by the National Natural Science Foundation of China(12171451,72091212).
Mendelian randomization(MR)is widely used in causal mediation analysis to control unmeasured confounding effects,which is valid under some strong assumptions.It is thus of great interest to assess the impact of violat...
Background Previous studies have found that patients with epilepsy are more likely to sufer impulsivity.However,the causal relationship between impulsivity and epilepsy is unknown.In this study,we conduct a bidirectio...
supported by the National Natural Science Foundation of China(grant numbers:82241044 and 82172152);the Science and Technology Commission of Shanghai(grant numbers:22692192200).
To the Editor,Previous studies have demonstrated close associations of specific immune cell profiles in the occurrence and development of COVID-19.[1,2]However,due to confounding factors and reverse causality in tradi...
Basic and Applied Basic Research Foundation of Guangdong Province,Grant/Award Numbers:2023A1515011768,2020A1515010221,2021A1515010535;National Natural Science Foundation of China,Grant/Award Numbers:82271818,81871275,82071831,82001714,81671591,81501389,81373182。
Background:Rheumatoid arthritis(RA)is a globally prevalent condition that has a significant impact on morbidity and mortality rates.As a result,there is growing interest in understanding its pathogenetic mechanisms,pa...
funded by the National Natural Science Foundation of China[12061058];National Natural Science Foundation of Ningxia[2023AAC02033];and the Key Research and Development Plan Project of Ningxia[2021BEG02026].
Metabolic syndrome(MS)is a common metabolic disorder status and defined as a pathology characterized by abdominal obesity,insulin resistance,hypertension,and hyperlipidemia(atherosclerosis)status[1].Evidence suggests ...
National Natural Science Foundation of China(No.81303095);Tianjin Graduate Student Research and Innovation Project(YJSKC-20231031).
Objective:To investigate the causal relationship between blood metabolite levels and the occurrence of prostate cancer by using two-sample Mendelian randomization method.Methods:Pooled data from public databases for g...