CERAMIDE

作品数:96被引量:228H指数:7
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相关领域:医药卫生生物学更多>>
相关作者:侯琦王红金鑫宋智琦肖汀更多>>
相关机构:复旦大学台北医学大学北京大学中国科学院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金重庆市自然科学基金更多>>
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Targeting sphingosine-1-phosphate signaling for cancer therapy被引量:7
《Science China(Life Sciences)》2017年第6期585-600,共16页Zuoquan Xie Hong Liu Meiyu Geng 
financial support from the National Natural Science Foundation of China(91229204);the Major Project of the Chinese National Programs for Fundamental Research and Development(2015CB910304)
Sphingosine-1-phosphate(S1P) is a potent pleotropic bioactive lipid mediator involved in immune cell trafficking, cell survival,cell proliferation, cell migration, angiogenesis and many other cellular processes. S1 P ...
关键词:sphingosine-1-phosphate sphingosine ceramide cancer inflammation immunity 
Ceramide induces release of mitochondrial proapop-totic proteins in caspase-dependent and -independent manner in HT-29 cells被引量:5
《Science China(Life Sciences)》2008年第1期66-71,共6页ZHANG XiaoFeng1, LI BaiXiang1, ZHANG Yang1 & LIU JiaRen2 1 Public Health College, Harbin Medical University, Harbin 150081, China 2 Department of Food Science, Cornell University, New York 14853-7201, USA 
Supported by the National Natural Science Foundation of China (Grant No. 30471447);Special-Purpose Scientific Research Foundation of Ph.D Subject in the Colleges and Universities of China (Grant No. 20060226004)
In this study, the release of mitochondrial proapoptotic intermembrane space proteins induced by ex-ogenous C2-ceramide in human colon carcinoma (HT-29) cell line was investigated. HT-29 cells were treated with 12.5, ...
关键词:C_2-ceramide mitochondria proapoptotic intermembrane space proteins mitochondrial membrane potential human colon carcinoma cells CASPASE 
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