BACKGROUND Cirrhosis is a significant risk factor for the development of hepatocellular carcinoma(HCC).Variability in HCC risk among patients with cirrhosis is notable,particularly when considering the diverse etiolog...
Supported by National Foundation for Science and Technology Development(NAFOSTED)-Ministry of Science and Technology,Viet Nam,No.108.02-2019.307.
BACKGROUND Human leukocyte antigen(HLA)class II molecules are cell surface receptor proteins found on antigen-presenting cells.Polymorphisms and mutations in the HLA gene can affect the immune system and the progressi...
Supported by the National Natural Science Foundation of China,No.82070574。
BACKGROUND Whether patients with compensated cirrhosis and low-level viremia(LLV)of hepatitis B should receive antiviral therapy(AVT)is still controversial,and published results are inconsistent.AIM To investigate the...
funded by Roche Diagnostics GmbH and partly supported by the“Center of Excellence for Metabolic Associated Fatty Liver Disease,National Sun Yat-sen University,Kaohsiung”,under The Featured Areas Research Center Program within the framework of the Higher Education Sprout Project by the Ministry of Education in Taiwan.
Background and Aims:Early detection of hepatocellular carcinoma(HCC)is crucial for improving survival in patients with chronic hepatitis.The GALAD algorithm combines gen-der(biological sex),age,α-fetoprotein(AFP),Len...
Cuiying Scientific and Technological Innovation Program of the Second Hospital,No.CY2021-BJ-A16 and No.CY2022-QN-A18;Clinical Medical School of Lanzhou University and Lanzhou Science and Technology Development Guidance Plan Project,No.2023-ZD-85.
BACKGROUND Liver cancer is one of the most prevalent malignant tumors worldwide,and its early detection and treatment are crucial for enhancing patient survival rates and quality of life.However,the early symptoms of ...
supported by the Shanghai Key Specialty of Traditional Chinese Clinical Medicine(grant number shslczdzk01201);the National Science and Technology Major Project(grant number 2018ZX10302204);Shanghai University of Traditional Chinese Medicine(grant number ZYJK FW201811013).
Background and Aims:The application of antifibrotic drugs to treat patients with chronic liver diseases who are receiving antiviral therapies for hepatocellular carcinoma(HCC)has not been established.Here,we aimed to ...
Hepatocellular carcinoma(HCC)is the most common primary tumor of the liver and often evolves from regenerating nodules in liver cirrhosis.While there have been significant advances in the treatment of HCC,the overall ...
Cirrhosis is frequently associated with sarcopenia,with reported rates of over 80%in patients with decompensated alcohol-related liver disease.Sarcopenia nega-tively impacts the prognosis of cirrhotic patients and aff...
Supported by Anhui Provincial Key Research and Development Plan,No.202104j07020048.
BACKGROUND The prognosis for hepatocellular carcinoma(HCC)in the presence of cirrhosis is unfavourable,primarily attributable to the high incidence of recurrence.AIM To develop a machine learning model for predicting ...
Cirrhosis with complications of liver decompensation and hepatocellular carcinoma(HCC)constitute a leading cause of morbidity and mortality worldwide.Portal hypertension is central to the progression of liver disease ...