CLOPIDOGREL

作品数:154被引量:581H指数:15
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相关领域:医药卫生更多>>
相关作者:邹建军邱声强张冰胡正刚王庄更多>>
相关机构:南京医科大学中国药科大学湖州市中心医院太原市中心医院更多>>
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相关基金:国家自然科学基金国家科技支撑计划国家重点基础研究发展计划河北省自然科学基金更多>>
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Analysis of the risk factors of clopidogrel response in a Han Chinese population undergoing percutaneous coronary intervention
《South China Journal of Cardiology》2016年第4期229-239,250,共12页李汉平 王楠 唐千捷 张梦珍 陈秀云 何国东 麦丽萍 陈纪言 钟诗龙 
supported by the National Science Foundation of China(No.81072701);Natural Science Foundation of Guangdong Province(No.10151008002000002/S2011010005830);key project of China(No.S2012020010947)
Background Clopidogrel is an antiplatelet drug, which requires the effiux pump P-glycoprotein (multidrug resistance-1, MDR1) encoded by the ABCB1 gene for intestinal absorption. However, recent studies evaluating th...
关键词:ABCB 1 CLOPIDOGREL genetic polymorphisms ANTIPLATELET percutaneous coronary intervention 
ADP-P2Y12 receptor antagonist sequential therapy for antiplatelet strategy in acute myocardial infarction patients with clobidogrel hyporesponse
《South China Journal of Cardiology》2015年第4期215-220,228,共7页李晓通 于忠祥 延荣强 马颖 王海洋 任永强 赵凯迪 侯方杰 范树信 张俊义 
supported by Medical scientific research Planning Project of Qingdao Shandong Province(No.2014-WJZD048)
Background Compared to clopidogrel, Ticagrelor significantly reduces the risk of cardiovascular events in patients with acute myocardial infarction (AMI) however increases the incidence of bleeding and the risk of f...
关键词:CLOPIDOGREL ticagrelor stent thrombosis 
Impact of concomitant use of proton pump inhibitors on anti-platelet therapy of clopidogrel in patients undergoing percutaneous coronary intervention
《South China Journal of Cardiology》2013年第4期219-223,236,共6页何鹏程 蒋磊 马雪芬 谭宁 周颖玲 陈纪言 
supported by Medical Scientific Research Foundation of Guangdong Province(No.A2010043)
Background In clopidogrel-treated patients undergoing percutaneous coronary intervention (PCI), the effect of concomitant use of PPIs on prognosis remains unclear. Methods From July 2010 to June 2012, 600 patients a...
关键词:proton pump inhibitors CLOPIDOGREL drug-eluting stents 
A combined anti-thrombotic therapy for thrombosis of mitral prosthetic valves
《South China Journal of Cardiology》2013年第2期109-115,156,共8页魏薇 董太明 郑智超 黄淑萍 
supported by Medical Research Foundation of Guangdong Province(No.B2011008)
Background For patients with prosthetic heart valves, thrombosis of the valves is dangerous. A second surgery for re-replacing the thrombosed valve is quite traumatic. There have been some researches on noninva-sive t...
关键词:mitral prosthetic valves THROMBOSIS CLOPIDOGREL WARFARIN low molecular weight heparin 
Clopidogrel hypersensitivity:A case report
《South China Journal of Cardiology》2013年第2期146-149,共4页杨帆 王红 
INTRODUCTION Dual antiplatelet therapy with aspirin and clopidogrel plays a key role in preventing recurrent atherothrombotic events in patients with acute coronary syndromes and those undergoing coronary stent implan...
关键词:CASE Clopidogrel hypersensitivity ORAL 
Comparison of benefit and safety between different loading dose of clopidogrel on elderly patients undergoing primary percutaneous cronary intervention for ST-segment elevation myocardial infarction被引量:1
《South China Journal of Cardiology》2012年第2期59-66,共8页何鹏程 谭宁 周颖玲 罗建方 陈纪言 杨大浩 
Background Despite the proven benefit of 600-mg loading dose of clopidogrel in patients with acute ST- segment elevation myocardial infarction (STEMI) who undergo primary percutaneous cronary intervention (PCI), t...
关键词:loading dose elopidogrel primary PCI STEMI 
Impact of prolonged dual antiplatelet therapy on patients after drug-eluting stents implantation
《South China Journal of Cardiology》2012年第1期1-7,共7页何鹏程 谭宁 杨大浩 陈纪言 罗建方 周颖玲 
Background Impact of dual antiplatelet therapy beyond 12 months on patients implanted with DES remains unsolved.Methods From January 2010 to June 2011,1873 patients who have been taking DAPT and free from death,myocar...
关键词:CLOPIDOGREL dual antiplatelet therapy drug-eluting stents 
Prasugrel versus clopidogrel in acute coronary syndrome patients undergoing percutaneous coronary intervention: A meta-analysis of randomized controlled trials被引量:1
《South China Journal of Cardiology》2010年第4期238-245,249,共9页张步春 车文良 刘伟静 徐亚伟 
Background Clopidogrel is beneficial after acute coronary syndrome. Recent studies suggest the superiority of prasugrel compared with clopidogrel. The enhanced platelet inhibition with prasugrel lead to a reduction in...
关键词:acute coronary syndrome META-ANALYSIS PRASUGREL CLOPIDOGREL 
Inhibitory Effect of Clopidogrel on Release of Soluble CD40 Ligand by ADP-activated Platelet in Patients With Non-ST-segment-elevation Acute Coronary Syndromes
《South China Journal of Cardiology》2008年第2期66-70,共5页魏薇 罗初凡 杜志民 
Objectives To investigate the inhibitory effect of clopidogrel on release of soluble CD40 ligand (sCD40L) by ADP-activated platelet in patients with non-ST-segment elevation acute coronary syndromes(NSTEACS). Meth...
关键词:CLOPIDOGREL acute coronary syndromes soluble CD40 ligand 
Effect of Clopidogrel on Platelet Membrane CD40 Ligand in Coronary Artery Disease Patients Undertaking Percutaneous Coronary Intervention被引量:1
《South China Journal of Cardiology》2007年第3期133-134,共2页Xinxia Zhang, Wen Duan, Wenbin Wei, Bijuan Kuang, Yunqi Zhang, Xiangguang Xu, Xuesong HuDepartment of Cardiology, Shenzhen Futian Hospital Affiliated of Guangdong Medical College,Shenzhen 518033, China 
shenzhen sciece-technique programs ( JH200507120939H)
Objectives To investigate the change and clinical significance of clopidogrel on platelet membrane CD40L in coronary artery disease patients before and after percutaneous coronary intervention(PCI). Methods 30 cases w...
关键词:PLATELET CD40 ligand CLOPIDOGREL percutaneous coronary intervention 
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