COPY_NUMBER

作品数：56被引量：88H指数：5
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Improvement in the risk assessment of oral leukoplakia through morphology-related copy number analysis被引量：3
《Science China(Life Sciences)》2021年第9期1379-1391,共13页Xiaotian Li Lu Liu Jianyun Zhang Ming Ma Lisha Sun Xuefen Li Heyu Zhang Jianbin Wang Yanyi Huang Tiejun Li 
supported by the National Natural Science Foundation of China(81671006,81300894,22050002,22050004);Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2019-I2M-5-038)。
Oral leukoplakia is the most common type of oral potentially malignant disorders and considered a precursor lesion to oral squamous cell carcinoma.However,a predictor of oral leukoplakia prognosis has not yet been ide...
关键词：oral leukoplakia copy number alteration prognosis prediction 
The completed macronuclear genome of a model ciliate Tetrahymena thermophila and its application in genome scrambling and copy number analyses被引量：4
《Science China(Life Sciences)》2020年第10期1534-1542,共9页Yalan Sheng Lili Duan Ting Cheng Yu Qiao Naomi AStover Shan Gao 
Supported by the Natural Science Foundation of Shandong Province (JQ201706);The Marine S&T Fund of Shandong Province for Pilot National Laboratory for Marine Science and Technology (Qingdao) (2018SDKJ0406-2);Fundamental Research Funds for the Central Universities (201841005);the Blue Life Breakthrough Program of LMBB of Qingdao National Laboratory for Marine Science and Technology (MS2018NO04);and National Institutes of Health (2P40OD010964).
The ciliate Tetrahymena thermophila has been a powerful model system for molecular and cellular biology.However,some investigations have been limited due to the incomplete closure and sequencing of the macronuclear ge...
关键词：Tetrahymena thermophila macronuclear genome 181 chromosomes DNA scrambling copy number 
Impact of copy number of distinct SV40PolyA segments on expression of a GFP reporter gene被引量：3
《Science China(Life Sciences)》2010年第5期606-612,共7页YIN Kang,WANG XiuFang,MA Huan,XIE Ying,FENG JingJing,YANG QinQing & Lü ZhanJun Hebei Key Lab of Laboratory Animal,Department of Genetics,Hebei Medical University,Shijiazhuang 050017,China 
supported by grants from Hebei Province Natural Science Foundation of China (Grant No C2008001065);Key Project of Hebei Province (Grant No 08276101D-90)
The presence of Alu repeats downregulates the expression of the green fluorescent protein(GFP) gene.We found that SV40PolyA(PolyA,240 bp),in either orientation,eliminated the inhibition of GFP gene expression induced ...
关键词：COPY number SV40PolyA REPEAT sequence GFP ALU 
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