supported by the Science&Technology Initiative projects,the STI 2030-Major Project (2021ZD0203400 to J.-F.C.);the STI 2030-Major Project (2022ZD0208300 to Z.W.);the National Natural Science Foundation of China (82101556 to X.Z.,82151308 to J.-F.C,31970948 and 31600859 to W.G.,81971031 to Z.L,818700073 to X.C.,81971064 to Y.Z.);the Research Fund for International Senior Scientists (82150710558 to J.-F.C.);the Key Research Project (2023C03079 to J.-F.C.)from Zhejiang Provincial Administration of Science&Technology,the Natural Science Foundation of Zhejiang Province of China grant (LQ22H090013 to X.Z.);the Start-up Fund (OJQDSP2022007 to J.-F.C.)from the Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine,Vision and Brain Health);the Program Project from the State Key Laboratory of Ophthalmology,Optometry and Vision Science,Wenzhou Medical University (Jo1-20190101 to J.-F.C.)。
Flickering light stimulation has emerged as a promising non-invasive neuromodulation strategy to alleviate neuropsychiatric disorders.However,the lack of a neurochemical underpinning has hampered its therapeutic devel...
supported by the National Natural Science Foundation of China(32030050 and 32192413);Guangdong High Level Innovation Research Institute(2021B0909050004);CAMS Innovation Fund for Medical Sciences(2019-I2M-5-082),and Shenzhen Sanming Project.
Nociceptive signals are usually transmitted to layer 4 neurons in somatosensory cortex via the spinothalamic-thalamocortical pathway.The layer 5 corticospinal neurons in sensorimotor cortex are reported to receive the...
the Agence Nationale de la Recherche (ANR- 15-CE13-0016-01 for AG);from Institut National du Cancer (INCA_6521 and INCA_11508 for AG and IB);from the fondation ARC pour la Recherche sur le Cancer (PGA120140200831 for AG and IB);Russian Science Foundation (grant #16-15-10288 for SNR);the Russian Science Foundation (grant #16-15-10221).
The actin cytoskeleton generates and senses forces. Here we report that branched actin networks from the cell cortex depend on ARPC1B-containing Arp2/3 complexes and that they are specifically monitored by type I coro...
The migration of cortical interneurons is a fundamental process for the establishment of cortical connectivity and its impairment underlies several neurological disorders. During development, these neurons are born in...
Serum inducible kinase (SNK), also known as polo-like kinase 2 (PLK2), is a known regulator of mitosis, synapto- genesis and synaptic homeostasis. However, its role in early cortical development is unknown. Herein...
Characterising the mechanisms of cell death following focal cerebral ischaemia has been hampered by a lack of an in vitro assay emulating both the apoptotic and necrotic features observed in vivo. The present study sy...