CYTOSKELETON

作品数:220被引量:501H指数:10
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相关领域:医药卫生生物学更多>>
相关作者:刘琳杨莹王建枝方征宇刘世杰更多>>
相关机构:浙江省人民医院华中科技大学福建医学院广西大学更多>>
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相关基金:国家自然科学基金高等学校学科创新引智计划国家重点基础研究发展计划中国博士后科学基金更多>>
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Host cytoskeleton and membrane network remodeling in the regulation of viral replication
《Biophysics Reports》2025年第1期34-45,共12页Xuedi Gao Xinming Chen Letian Yu Shuangshuang Zhao Yaming Jiu 
Viral epidemics pose major threats to global health and economies.A hallmark of viral infection is the reshaping of host cell membranes and cytoskeletons to form organelle-like structures,known as viral factories,whic...
关键词:Viral replication factory Cytoskeleton Actin filaments MICROTUBULES Intermediate filaments Rearrangement of cellular membranes 
Suppression of Cell Traction Force and Enhanced Force Polarity are Key Factors in Vascular Smooth Muscle Cell Differentiation Induced by Low Serum Culture
《Journal of Biosciences and Medicines》2025年第2期243-255,共13页Kazuaki Nagayama Harunobu Tatsuno 
Vascular smooth muscle cells (VSMCs) in the arterial walls play important roles in regulating vascular contraction and dilation. VSMCs actively remodel the arterial walls and dedifferentiate from the contractile to th...
关键词:Cell Biomechanics MECHANOBIOLOGY PHENOTYPE CYTOSKELETON Traction Force Microscopy 
The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons
《Neural Regeneration Research》2025年第1期209-223,共15页Shi-Yan Sun Lingyun Nie Jing Zhang Xue Fang Hongmei Luo Chuanhai Fu Zhiyi Wei Ai-Hui Tang 
supported by the National Key Research and Development Program of China,No.2021ZD0202503(to AHT);the National Natural Science Foundation of China,Nos.31872759(to AHT)and 32070707(to CF);Shenzhen Science and Technology Program,No.RCJC20210609104333007(to ZW);Shenzhen-Hong Kong Institute of Brain Science,Shenzhen Fundamental Research Institutions,No.2021SHIBS0002(to ZW).
Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and memory.Kinesin-4 KIF21A helps organize the microtubule-actin network at th...
关键词:ACTIN CYTOSKELETON dendrite KANK1 KIF21A MICROTUBULE spine morphology SPINE synaptic plasticity talin1 
CCDC178-mediated cytoskeleton assembly is required for spermiogenesis in mice
《Genes & Diseases》2024年第6期56-59,共4页Fucheng Dong Xiuge Wangg Tao Huangg Yingying Yin Sai Xiao Yanjie Ma Huafang Wei Bingbing Wu Ruidan Zhang Liying Wang Xuejiang Guo Fei Gao Chao Liu Hongbin Liu Jianguo Zhao Wei Li 
supported by the National Science Fund for Distinguished Young Scholars of China (No.81925015);the National Natural Science Foundation of China (No.91649202);the Shandong Provincial Key Research&Development Program (China) (No.2018YFJH0504);the open fund of the State Key Laboratory of Reproductive Medicine (China) (SKLRM-K202201).
Infertility affects around 8%-12%of couples globally,and in about 50%of these cases,male factors are either the primary cause or contribute significantly to infertility.Any defects during spermiogenesis may result in ...
关键词:INFERTILITY globally CASES 
Autophagy mediated tubulobulbar complex components degradation is required for spermiation
《Fundamental Research》2024年第6期1557-1567,共11页Liying Wang Ruidan Zhang Bingbing Wu Yang Yu Wei Li Shiguo Li Chao Liu 
supported by the National Science Fund for Distinguished Young Scholars(81925015);the Youth Innovation Promotion Association of CAS(2018109).
Spermiation is the process that releases mature spermatids from Sertoli cells into the lumen of the seminiferous tubule.Tubulobulbar complexes(TBCs)are elaborate cytoskeleton-related structures that are indispensable ...
关键词:AUTOPHAGY SPERMIATION Tubulobulbar complexes Cytoskeleton degradation Sertoli cells LYSOSOME 
Cellular basis of legume-rhizobium symbiosis
《Plant Communications》2024年第11期41-53,共13页Xiaxia Zhang Jingxia Wu Zhaosheng Kong 
National Natural Science Foundation of China for Z.K.(grant nos.31925003,32230007,32241045)and X.Z.(grant no.32000142).
The legume-rhizobium symbiosis represents the most important system for terrestrial biological nitrogen fixation on land.Efficient nitrogen fixation during this symbiosis depends on successful rhizobial infection and ...
关键词:root nodule symbiosis infection threads symbiosomes rhizobia endosymbiosis cell wall-membrane system-cytoskeleton continuum 
Endothelial dysfunction:mechanisms and contribution to diseases被引量:1
《Acta Pharmacologica Sinica》2024年第10期2023-2031,共9页Amir Ajoolabady Domenico Pratico Jun Ren 
supported by the National Natural Science Foundation of China(82130011,92249301).
The endothelium,lining the inner surface of blood vessels and spanning approximately 3 m^(2),serves as the largest organ in the body.Comprised of endothelial cells,the endothelium interacts with other bodily component...
关键词:endothelial dysfunction inflammation extracellular matrix and cytoskeleton metabolic conditions HYPERGLYCEMIA 
Traction force with extracellular matrix mediated by cytoskeleton influences metastasis through SLC8A1 induced Wnt-b-catenin pathway in endometrial cancer
《Genes & Diseases》2024年第5期98-101,共4页Xingchen Li Xin Xu Jianliu Wang 
the National Natural Science Foundation of China(No.82103419,and 82230050);the Research and Development Fund of Peking University People’s Hospital,Beijing,China(No.RS2021-05,and RDY2021-13).
Endometrial cancer(EC)is one of the most prominent malignancies in gynecology.Unfortunately,despite these advancements in understanding EC pathogenesis,mortality rates have not decreased.Traction force(TF)refers to en...
关键词:ENDOMETRIAL METASTASIS ENDOGENOUS 
The actin motor protein OsMYA1 associates with OsExo70H1 and contributes to rice secretory defense by modulating OsSyp121 distribution
《Journal of Integrative Plant Biology》2024年第9期2058-2075,共18页Yuan‐Bao Li Chengyu Liu Ningning Shen Shuai Zhu Xianya Deng Zixuan Liu Li‐Bo Han Dingzhong Tang 
funded by the National Key Research and Development Program of China (2022YFF1001500);the National Natural Science Foundation of China (grant numbers 31970284,31900385);the Natural Science Foundation of Fujian Province,China (2023J01483, 2022J01616);the Distinguished Young Scientists Fund of Fujian Agriculture and Forestry University of China (xjq202121);the Fujian Provincial Science and Technology Key Project (2022NZ030014)
Magnaporthe oryzae(M.oryzae)is a devastating hemibiotrophic pathogen.Its biotrophic invasive hyphae(IH)are enclosed in the extrainvasive hyphal membrane produced by plant cells,thus generating a front line of the batt...
关键词:CYTOSKELETON plant defense mechanism rice blast vesicle delivery 
Biological Evaluation of Lysionotin:a Novel Inhibitor of 5-Lipoxygenase for Anti-glioma
《Chinese Journal of Integrative Medicine》2024年第9期826-834,共9页SHAO Xin-xin CHEN Cong LIU Jie LI Qing-jun HE Shan QI Xiang-hua FU Xian-jun WANG Zhen-guo 
Supported by the Natural Science Foundation of China(No.81473369);the National Key Research and Development Program of China(No.2017YFC1702703);Jinan City Science and Technology SMES Innovation Ability Improvement Project,“Traditional Chinese Medicine Digital Humanities Youth Innovation Team”of College and University in Shandong Province(No.2023RW093)。
Objective:To explore the potential mechanism of lysionotin in treating glioma.Methods:First,target prediction based on Bernoulli Naïve Bayes profiling and pathway enrichment was used to predict the biological activity...
关键词:5-lipoxygenase inhibitor lysionotin 5-LIPOXYGENASE leukotriene B4 calcium ion CYTOSKELETON 
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