云南高校图书馆联盟文献共享服务平台- 5-LIPOXYGENASE

5-LIPOXYGENASE: 作品数：35被引量：134H指数：8; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：朱大岭曲迅赵宝华王亚婷王福生更多>>; 相关机构：哈尔滨医科大学山东大学河北师范大学重庆医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金更多>>

Arachidonate 15-lipoxygenase:A promising therapeutic target for alleviating inflammation in acute pancreatitis: 《World Journal of Gastroenterology》2025年第15期131-135,共5页Duygu Kirkik Sevgi Kalkanli Tas; This article discusses the significant findings from the study on the transfection of arachidonate 15-lipoxygenase(ALOX15)and its therapeutic potential in managing acute pancreatitis(AP).The research highlights the ro...; 关键词：Acute pancreatitis Arachidonate 15-lipoxygenase INFLAMMATION APOPTOSIS AUTOPHAGY

Transfection of 12/15-lipoxygenase effectively alleviates inflammatory responses during experimental acute pancreatitis: 《World Journal of Gastroenterology》2024年第42期4544-4556,共13页Hong-Wei Sun Yong-Yu Bai Zhen-Liu Qin Ri-Zhao Li Tinotenda Blessing Madzikatire Percy David Papa Akuetteh Qiang Li Hong-Ru Kong Yue-Peng Jin; National Health Commission Research Fund,No.WKJ-ZJ-2342;National Natural Science Foundation of China,No.81900583;Science and Technology Plan Project of Wenzhou,No.Y20180103.; BACKGROUND Acute pancreatitis(AP),the initially triggered inflammatory process in the pancreas,can be life-threatening.It has been reported that 15-lipoxygenase may promote the removal of damaged intracellular compone...; 关键词：Acute pancreatitis CERULEIN 12/15-lipoxygenase APOPTOSIS AUTOPHAGY

Biological Evaluation of Lysionotin:a Novel Inhibitor of 5-Lipoxygenase for Anti-glioma: 《Chinese Journal of Integrative Medicine》2024年第9期826-834,共9页SHAO Xin-xin CHEN Cong LIU Jie LI Qing-jun HE Shan QI Xiang-hua FU Xian-jun WANG Zhen-guo; Supported by the Natural Science Foundation of China(No.81473369);the National Key Research and Development Program of China(No.2017YFC1702703);Jinan City Science and Technology SMES Innovation Ability Improvement Project,“Traditional Chinese Medicine Digital Humanities Youth Innovation Team”of College and University in Shandong Province(No.2023RW093)。; Objective:To explore the potential mechanism of lysionotin in treating glioma.Methods:First,target prediction based on Bernoulli Naïve Bayes profiling and pathway enrichment was used to predict the biological activity...; 关键词：5-lipoxygenase inhibitor lysionotin 5-LIPOXYGENASE leukotriene B4 calcium ion CYTOSKELETON

Codiaeum Variegatum Hydro Alcoholic Leaf Extracts and Their Fractions Inhibit Pro-Inflammatory Mediators in Vitro: 《Journal of Biosciences and Medicines》2023年第5期40-54,共15页Sylvain Pechangou Nsangou Charifa Ngbetkom Mandou Carine Matsigang Fondjou Vigny Sayal Ngohoba Edie Brice Enang II Ibrahim Njingou Emmanuel Mfotie Njoya Frederic Nico Njayou Paul Moundipa Fewou; Codiaeum variegatum has been widely investigated for its biological proprieties ranging from the antiamoebic potential to the phytochemical analysis. The aim of the present study was to evaluate the anti-inflammatory ...; 关键词：C. variegatum ANTI-INFLAMMATORY 5-LIPOXYGENASE NO TNF-α

Study on the effect of Danbei Yifei formula on pulmonary fibrosis based on network pharmacology and molecular docking technology: 《Journal of Hainan Medical University》2022年第5期41-46,共6页Xiao-Jun Cai Bai-Hua Jiang Zhen-Hua Lu Tao Wang Bi-Hai Zhang Xu-Ling Wang; Applied Technology Research and Development Project of Heilongjiang Province(No.GA19C1080)。; Objective:To determine the pharmacodynamic material basis and mechanism of Danbei Yifei formula on pulmonary fibrosis.Methods:Starting with the clear absorbed components of Danbei Yifei formula or the potential effect...; 关键词：Danbei Yifei formula Pulmonary fibrosis Network pharmacology Protocatechuic acid Arachidonate 5-lipoxygenase

QSAR modeling of benzoquinone derivatives as 5-lipoxygenase inhibitors被引量：1: 《Food Science and Human Wellness》2019年第1期53-62,共10页T.K.Shameera Ahamed Vijisha K.Rajan K.Muraleedharan; The inhibitors of 5-LOX control the overproduction of pro-inflammatory mediators known as leukotrienes(LTs)and thus have therapeutic relevance in the treatment of various diseases like asthma,rheumatoid arthritis,infl...; 关键词：5-LIPOXYGENASE BENZOQUINONE 2D-QSAR 3D-QSAR Molecular docking

5-Lipoxygenase and cysteinyl leukotriene receptors in neuroinflammation and neuronal injury: 《中国药理学与毒理学杂志》2018年第9期709-710,共2页LI Cheng-tan ZHANG Si-ran WANG Yu-xi ZHAO Jian-bo ZHENG Wei WANG Yan-fang ZHANG Li-hui; The project supported by National Natural Science Foundation of China(81671188);Zhejiang Provincial Natural Science Foundation of China(LY12H31010);Key Laboratory of Hangzhou City Project(20090233T12); Brian ischemic injury and central neurodegenerative diseases as leading contributors to disability and death have become a majorclinical and public health concern worldwide.Neuroinflammation plays a pivotal role in th...; 关键词：5-LIPOXYGENASE cysteinyl leukotrienereceptor INFLAMMATION NEURONS

Preventive effects of cannabis on neurotoxic and hepatotoxic activities of malathion in rat: 《Asian Pacific Journal of Tropical Medicine》2018年第4期272-279,共8页Omar M.E.Abdel-Salam Amany A Sleem Eman R Youness Fatma A.Morsy; Objective: To investigate the effect of Cannabis sativa extract on the development of neuroand hepato-toxicity caused by malathion injection in rats. Methods: The extract of Cannabis sativa was obtained from the plant...; 关键词：Cannabis sativa MALATHION Liver damage Brain damage Oxidative stress PARAOXONASE 5-LIPOXYGENASE

Phytochemistry and potential therapeutic actions of Boswellic acids:A mini-review被引量：3: 《Asian Pacific Journal of Tropical Biomedicine》2017年第6期513-523,共11页Farah Iram Shah Alam Khan Asif Husain; The pentacyclic triterpenic acids isolated from the oleo gum resin of various Boswellia species are collectively called as Boswellic acids(BA).The oleo gum resin obtained from Indian variety i.e.Boswellia serrata(Fami...; 关键词：Boswellia serrata Boswellic acids INFLAMMATION Leukotriene synthesis 5-LIPOXYGENASE

The effects of 5-lipoxygenase inhibitor and cysteinyl leukotriene receptor 1 antagonist on 1-methyl-4-phenylpyridine-induced neurotoxicity: 《中国药理学与毒理学杂志》2016年第10期1022-1023,共2页ZHANG Xiao-yan LI Chen-tan WANG Yan-fang ZHAO Jian-bo WEI Er-qing ZHANG Li-hui; The project supported National Natural Science Foundation of China(81273491);the Zhejiang Provincial Natural Science Foundation(LY12H31010); OBJECTIVE Previously we demonstrated the neuroprotective effect of 5-lipoxygenase(5-LOX)inhibitor as well as cysteinyl leukotriene receptor 1(Cys LT1)antagoniston rotenone-induced microglial activation and neuronal de...; 关键词：MPP+ NEUROTOXICITY PC12 cell 5-LIPOXYGENASE cysteinyl leukotriene receptor

5-LIPOXYGENASE