云南高校图书馆联盟文献共享服务平台- CERULEIN

CERULEIN: 作品数：16被引量：60H指数：4; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：周慧黄丹丹董育玮赵航张汝玲更多>>; 相关机构：第二军医大学上海市第一人民医院更多>>; 相关期刊：《World Journal of Gastroenterology》《Hepatobiliary & Pancreatic Diseases International》《实验动物与比较医学》《Asian Pacific Journal of Tropical Biomedicine》更多>>; 相关基金：国家自然科学基金广西壮族自治区自然科学基金更多>>

Trypsin in pancreatitis:The culprit,a mediator,or epiphenomenon?: 《World Journal of Gastroenterology》2024年第41期4417-4438,共22页Anna S Gukovskaya Markus M Lerch Julia Mayerle Matthias Sendler Baoan Ji Ashok K Saluja Fred S Gorelick Ilya Gukovsky; Pancreatitis is a common,life-threatening inflammatory disease of the exocrine pancreas.Its pathogenesis remains obscure,and no specific or effective treatment is available.Gallstones and alcohol excess are major etio...; 关键词：Pancreatic acinar cell Hereditary pancreatitis Autophagy Endolysosomal system CHOLECYSTOKININ CERULEIN CATHEPSIN

Transfection of 12/15-lipoxygenase effectively alleviates inflammatory responses during experimental acute pancreatitis: 《World Journal of Gastroenterology》2024年第42期4544-4556,共13页Hong-Wei Sun Yong-Yu Bai Zhen-Liu Qin Ri-Zhao Li Tinotenda Blessing Madzikatire Percy David Papa Akuetteh Qiang Li Hong-Ru Kong Yue-Peng Jin; National Health Commission Research Fund,No.WKJ-ZJ-2342;National Natural Science Foundation of China,No.81900583;Science and Technology Plan Project of Wenzhou,No.Y20180103.; BACKGROUND Acute pancreatitis(AP),the initially triggered inflammatory process in the pancreas,can be life-threatening.It has been reported that 15-lipoxygenase may promote the removal of damaged intracellular compone...; 关键词：Acute pancreatitis CERULEIN 12/15-lipoxygenase APOPTOSIS AUTOPHAGY

Ghrelin inhibits IKKβ/NF-κB activation and reduces pro-inflammatory cytokine production in pancreatic acinar AR42J cells treated with cerulein被引量：3: 《Hepatobiliary & Pancreatic Diseases International》2021年第4期366-375,共10页Ren-Jie Chang Hui-Lin Wang Meng-Bin Qin Zhi-Hai Liang Jia-Ping He Yu-Le Wei Hong-Zong Fu Guo-Du Tang; This study was supported by grants from the National Nat-ural Science Foundation of China(81260087 and 81560111);Guangxi Natural Science Foundation(2017GXNSFAA198068).; Background: Previous studies have provided conflicting results regarding whether the serum ghrelin concentration can reflect the severity of acute pancreatitis(AP). The present study examined the correlation between t...; 关键词：Acute pancreatitis GHRELIN Inflammatory cytokine Acinar cells

Hydroalcoholic extract of licorice(Glycyrrhiza glabra L.) root attenuates ethanol and cerulein induced pancreatitis in rats: 《Asian Pacific Journal of Tropical Biomedicine》2019年第10期424-433,共10页Sarmishta Srikantam Geetha Arumugam; Objective:To evaluate the therapeutic potential of hydroalcoholic extract of licorice root against ethanol and cerulein induced chronic pancreatitis in rats.Methods:The phytochemical profile of hydroalcoholic extract ...; 关键词：PANCREATITIS ROS Inflammation GLYCYRRHIZA glabra HPLC GC-MS

Oxidative stress and inflammatory signaling in cerulein pancreatitis被引量：23: 《World Journal of Gastroenterology》2014年第46期17324-17329,共6页Ji Hoon Yu Hyeyoung Kim; Supported by National Research Foundation of Korea grant funded by the Korea government No.2007-0056092; Oxidative stress is considered to be an important regulator of the pathogenesis of acute pancreatitis. Reactive oxygen species (ROS) regulate the activation of inflammatory cascades, the recruitment of inflammatory ce...; 关键词：Reactive oxygen species Inflammatory signaling Cerulein pancreatitis

Evidence for a role of mitogen-activated protein kinases in the treatment of experimental acute pancreatitis被引量：3: 《World Journal of Gastroenterology》2014年第44期16535-16543,共9页Natasha Irrera Alessandra Bitto Monica Interdonato Francesco Squadrito Domenica Altavilla; Acute pancreatitis(AP) is an inflammatory disease characterized by acute inflammation and necrosis of the pancreatic parenchyma. AP is often associated with organ failure, sepsis, and high mortality. The pathogenesis ...; 关键词：Experimental acute pancreatitis Mitogen-activated protein kinases Mitogen-activated protein kinases inhibitors CYTOKINES CHOLECYSTOKININ CERULEIN

Effects of melatonin on the oxidative damage and pancreatic antioxidant defenses in ceruleininduced acute pancreatitis in rats被引量：1: 《Hepatobiliary & Pancreatic Diseases International》2014年第4期442-446,共5页Cristina Carrasco Ana Beatriz Rodríguez José A Pariente; supported by grants from MICINNFEDER(BFU2010-15049);Gobierno de Extremadura(Re:GRU10003);Plan of Recruitment and Training of Human Resources on Research of University of Extremadura(1076); BACKGROUND： Oxidative stress is recognized as a pivotal effector of several pathogenic processes, including acute pancreatitis. Reactive oxygen species not just cause damage on the main cellular components, but also ...; 关键词：acute pancreatitis antioxidants cerulein melatonin oxidative stress

Long-term aspirin pretreatment in the prevention of cerulein-induced acute pancreatitis in rats被引量：6: 《World Journal of Gastroenterology》2013年第19期2894-2903,共10页Ibrahim Akyazi Evren Eraslan Ahmet Gülubuk Elif Ergül Ekiz Zeynep L rakli Damla Haktanir Deniz Aktaran Bala Mete zkurt Erdal Matur Mukaddes zcan; Supported by The Istanbul University Department of Scientific Research Projects,Grant No. 3101; AIM:To investigate the effects of long term pretreatment with low-,medium-and high-dose aspirin(acetylsalicylic acid,ASA) on a model of acute pancreatitis(AP) induced in rats.METHODS:Forty male Wistar rats were used.T...; 关键词：ASPIRIN Acute PANCREATITIS CERULEIN Antioxidant CYTOKINES

三种慢性胰腺炎大鼠模型的观察与比较被引量：2: 《实验动物与比较医学》2012年第4期270-273,共4页赵航黄丹丹董育玮张汝玲周慧; 国家自然科学基金项目（81000165）; 目的观察与比较雨蛙素注射、胰胆管结扎及精氨酸注射三种慢性胰腺炎造模方法。方法将大鼠随机分入雨蛙素注射（Cerulein）组，胰胆管结扎（Ligatjon）组，精氨酸注射组（Arginine）。采取相应方法制作慢性胰腺炎动物模型，在造模后3d、7...; 关键词：慢性胰腺炎动物模型大鼠雨蛙素(Cerulein) 结扎(Ligation) 精氨酸(Arginine) 评价

Chronic stress sensitizes rats to pancreatitis induced by cerulein:Role of TNF-α被引量：7: 《World Journal of Gastroenterology》2010年第44期5565-5581,共17页Marcelo G Binker Andres A Binker-Cosen Daniel Richards Herbert Y Gaisano Rodica H de Cosen Laura I Cosen-Binker; Supported by KB Certification International; AIM:To investigate chronic stress as a susceptibility factor for developing pancreatitis,as well as tumor necrosis factor-α (TNF-α) as a putative sensitizer.METHODS:Rat pancreatic acini were used to analyze the infl...; 关键词：PANCREATITIS STRESS Tumor necrosis factor-α

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