supported by the National Natural Science Foundation of China(No.30772551);the Science &Technology Program of Guangdong Province(No.2011B031800178);National High-technology Research and Development Program of China(No.2012AA02A508);Specialized Research Fund for the Doctoral Program of Higher Education(No.20110171110076)
O6-methylguanine DNA methyltransferase(MGMT) can remove DNA alkylation adducts, thereby repairing damaged DNA and contributing to the drug resistance of gliomas to alkylating agents. In addition, glioma stem-like cell...
The current World Health Organization classification system of primary brain tumors is solely based on morphologic criteria. However, there is accumulating evidence that tumors with similar histology have distinct mol...
Postoperative external beam radiotherapy was considered the standard adjuvant treatment for patients with glioblastoma multiforme until the advent of using the drug temozolomide(TMZ) in addition to radiotherapy. High-...
supported by National Natural Science Foundation of China (No.91130009);Science and Technology Planning Project of Guangdong Province of China(No.2003A3080503)
Systems biology has become an effective approach for understanding the molecular mechanisms underlying the development of lung cancer.In this study,sequences of 100 non-small cell lung cancer (NSCLC)-related proteins ...