DOXYCYCLINE

作品数：68被引量：168H指数：7
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Generation and Characterization of a Transgenic Zebrafish Expressing the Reverse Tetracycline Transactivator
《Journal of Genetics and Genomics》2013年第10期523-531,共9页Qilin Gu Xiaojie Yang Xiaozhen He Qing Li Zongbin Cui 
supported by the grants from the National Basic Research Program of China(No.2012CB944500);the National Natural Science Foundation of China(No.31171390 to Z.Cui)
Conditional expression of a target gene during zebrafish development is a powerful approach to elucidate gene functions. The tetracycline-controlled systems have been successfully used in the modulation of gene expres...
关键词：Zebrafish TRANSGENE Tet-on system Reverse Tet transactivator DOXYCYCLINE 
A stringent dual control system overseeing transcription and activity of the Cre recombinase for the liver-specific conditional gene knock-out mouse model被引量：3
《Journal of Genetics and Genomics》2008年第7期431-439,共9页Yu Wu Yinghua He Hongyu Zhang Xinlan Dai Xiaoyu Zhou Jun Gu Guan Wang Jingde Zhu 
supported by Shanghai Science Foundation grants,National Science Foundation of China(No.30570850 and 10574134);National Research Program for Basic Research of China(No.2004CB518804);National Research Program for High Technology(No.2006AA02Z-320 and 2006AA 02Z197);European 6th Program(LSHBCT-2005-019067).
Liver cancer is one of the most threatening diseases in Chinese population. Just like in other tissues, tumor initiation and development in liver involve multiple steps of genetic and epigenetic alterations with sever...
关键词：Cre/loxP TET-OFF hepatocyte-specific DOXYCYCLINE 4-OHT C/EBβ 
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